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Top Articles

#TitleJournalYearCitations
1Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 InflammasomeCell2015753
2Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunityNature Immunology2018716
3Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacyProceedings of the National Academy of Sciences of the United States of America2016617
4Guidelines for the use of flow cytometry and cell sorting in immunological studies*European Journal of Immunology2017505
5Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disordersJournal of Experimental Medicine2017485
6Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progressionCellular and Molecular Life Sciences2016473
7Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammationJournal of Experimental Medicine2014360
8RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathwayNature Immunology2014273
9CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activationNature Communications2017246
10m6A mRNA methylation sustains Treg suppressive functionsCell Research2018243
11Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124–2HGAutophagy2017222
12NK Cell ExhaustionFrontiers in Immunology2017221
13Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activityNature Immunology2015218
14Ultrathin Polypyrrole Nanosheets via Space-Confined Synthesis for Efficient Photothermal Therapy in the Second Near-Infrared WindowNano Letters2018215
15Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicinesNano Today2016208
16Developmental and Functional Control of Natural Killer Cells by CytokinesFrontiers in Immunology2017203
17Orchestration of NLRP3 Inflammasome Activation by Ion FluxesTrends in Immunology2018158
18Liver natural killer cells: subsets and roles in liver immunityCellular and Molecular Immunology2016150
19Facile syntheses of conjugated polymers for photothermal tumour therapyNature Communications2019149
20Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathwaysCellular and Molecular Immunology2017144
21Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 InflammasomeJournal of Immunology2018143
22Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC InhibitorsCancer Cell2017136
23Facile Generation of Tumor‐pH‐Labile Linkage‐Bridged Block Copolymers for Chemotherapeutic DeliveryAngewandte Chemie - International Edition2016133
24NK cell education via nonclassical MHC and non-MHC ligandsCellular and Molecular Immunology2017131
25TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunityJournal of Experimental Medicine2017120
26The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma ProgressionImmunity2017115
27Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cellsJournal of Controlled Release2015106
28KDM5 histone demethylases repress immune response via suppression of STINGPLoS Biology2018106
29Tumor acidity-sensitive linkage-bridged block copolymer for therapeutic siRNA deliveryBiomaterials201698
30Diversity of tissue-resident NK cellsSeminars in Immunology201797
31γδT Cells Drive Myeloid-Derived Suppressor Cell–Mediated CD8+ T Cell Exhaustion in Hepatitis B Virus–Induced ImmunotoleranceJournal of Immunology201493
32Kupffer Cells Support Hepatitis B Virus–Mediated CD8+ T Cell Exhaustion via Hepatitis B Core Antigen–TLR2 Interactions in MiceJournal of Immunology201593
33Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cellsBiomaterials201690
34Differential phenotypic and functional properties of liver-resident NK cells and mucosal ILC1sJournal of Autoimmunity201690
35Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivoBiomaterials201588
36Hierarchical Multiplexing Nanodroplets for Imaging-Guided Cancer Radiotherapy via DNA Damage Enhancement and Concomitant DNA Repair PreventionACS Nano201883
37AI-2 quorum sensing negatively regulates rbf expression and biofilm formation in Staphylococcus aureusInternational Journal of Medical Microbiology201780
38The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferationNature Communications201780
39Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast CancerJournal of Biological Chemistry201579
40MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγ*Scientific Reports201575
41Rationally designed rapamycin-encapsulated ZIF-8 nanosystem for overcoming chemotherapy resistanceBiomaterials202074
42Enhancing tumor chemotherapy and overcoming drug resistance through autophagy-mediated intracellular dissolution of zinc oxide nanoparticlesNanoscale201967
43Nitric Oxide Induces Immunogenic Cell Death and Potentiates Cancer ImmunotherapyACS Nano202266
44Tumor Therapeutics Work as Stress Inducers to Enhance Tumor Sensitivity to Natural Killer (NK) Cell Cytolysis by Up-regulating NKp30 Ligand B7-H6Journal of Biological Chemistry201564
45Natural killer T cells play a necessary role in modulating of immune-mediated liver injury by gut microbiotaScientific Reports201463
46The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with ImmunoscoreOncotarget201560
47MicroRNA100 Inhibits Self-Renewal of Breast Cancer Stem–like Cells and Breast Tumor DevelopmentCancer Research201459
48Rapid method for protein quantitation by Bradford assay after elimination of the interference of polysorbate 80Analytical Biochemistry201659
49Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor designBiochemical and Biophysical Research Communications201759
50Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuseScientific Reports201658