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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
2Inflammation in diabetic retinopathyProgress in Retinal and Eye Research2011879
3Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2Nature Immunology2014373
4Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATPNature Communications2016320
5Cholesterol in the retina: The best is yet to comeProgress in Retinal and Eye Research2014229
6Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ EffluxJournal of Immunology2015195
7FusariumandCandida albicansBiofilms on Soft Contact Lenses: Model Development, Influence of Lens Type, and Susceptibility to Lens Care SolutionsAntimicrobial Agents and Chemotherapy2008188
8Stem Cell Therapy Restores Transparency to Defective Murine CorneasStem Cells2009186
9n−3 Fatty Acid Supplementation for the Treatment of Dry Eye DiseaseNew England Journal of Medicine2018185
10Glycation‐altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age‐related disease (in nondiabetics)Aging Cell2012161
11Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus KeratitisPLoS Pathogens2010159
12The RodA Hydrophobin on Aspergillus fumigatus Spores Masks Dectin-1– and Dectin-2–Dependent Responses and Enhances Fungal Survival In VivoJournal of Immunology2013154
13Increased Resistance of Contact Lens-Related Bacterial Biofilms to Antimicrobial Activity of Soft Contact Lens Care SolutionsCornea2009143
14Fungal antioxidant pathways promote survival against neutrophils during infectionJournal of Clinical Investigation2012132
15Matrix Metalloproteinase-8 Facilitates Neutrophil Migration through the Corneal Stromal Matrix by Collagen Degradation and Production of the Chemotactic Peptide Pro-Gly-ProAmerican Journal of Pathology2008127
16Primary amines protect against retinal degeneration in mouse models of retinopathiesNature Chemical Biology2012125
17Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1Journal of Biological Chemistry2011124
18The pathogenic role of Maillard reaction in the aging eyeAmino Acids2012123
19Autophagy Protects the Retina from Light-induced DegenerationJournal of Biological Chemistry2013122
20TLR4 and TLR5 on Corneal Macrophages Regulate Pseudomonas aeruginosa Keratitis by Signaling through MyD88-Dependent and -Independent PathwaysJournal of Immunology2010120
21Onchocerciasis: the Role of Wolbachia Bacterial Endosymbionts in Parasite Biology, Disease Pathogenesis, and TreatmentClinical Microbiology Reviews2011120
22Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1Journal of Immunology2012118
23Variation in the Lysyl Oxidase (LOX) Gene Is Associated with Keratoconus in Family-Based and Case-Control Studies2012116
24Acetylation of Retinal Histones in Diabetes Increases Inflammatory ProteinsJournal of Biological Chemistry2012106
25Structural and Biochemical Characterization of Mycobacterium tuberculosis CYP142Journal of Biological Chemistry2010104
26Expression of Innate and Adaptive Immune Mediators in Human Corneal Tissue Infected With Aspergillus or FusariumJournal of Infectious Diseases2011104
27Toll-like Receptors at the Ocular SurfaceOcular Surface2008102
28The Structure of Mycobacterium tuberculosis CYP125Journal of Biological Chemistry2009102
29Host Defense at the Ocular SurfaceInternational Reviews of Immunology2013102
30Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporumPLoS Pathogens2013101
31EK (DLEK, DSEK, DMEK): New Frontier in Cornea SurgeryAnnual Review of Vision Science201798
32Atomic force microscopy: A multifaceted tool to study membrane proteins and their interactions with ligandsBiochimica Et Biophysica Acta - Biomembranes201492
33Tyrosine phosphatase SHP-2 mediates C-type lectin receptor–induced activation of the kinase Syk and anti-fungal TH17 responsesNature Immunology201592
34Spatial Distribution of the Pathways of Cholesterol Homeostasis in Human RetinaPLoS ONE201291
35Aspergillus and Fusarium Corneal Infections Are Regulated by Th17 Cells and IL-17–Producing NeutrophilsJournal of Immunology201487
36ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial SurvivalJournal of Immunology201286
37Cholestenoic Acid Is an Important Elimination Product of Cholesterol in the Retina: Comparison of Retinal Cholesterol Metabolism with That in the Brain201184
38Cytochromes P450: Roles in DiseasesJournal of Biological Chemistry201384
39Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's diseaseNeuropharmacology201781
40Corneal Endothelial Cell Loss and Morphometric Changes 5 Years after Phacoemulsification with or without CyPass Micro-StentAmerican Journal of Ophthalmology201980
41Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyesNature Medicine201078
42Effects of a Disrupted Blood-Brain Barrier on Cholesterol Homeostasis in the BrainJournal of Biological Chemistry201478
43MyD88 Functions as a Negative Regulator of TLR3/TRIF-induced Corneal Inflammation by Inhibiting Activation of c-Jun N-terminal KinaseJournal of Biological Chemistry200877
44Retinal Photodamage Mediated by All‐trans‐retinal†Photochemistry and Photobiology201274
45Retinal Pigmented Epithelial Cells Obtained from Human Induced Pluripotent Stem Cells Possess Functional Visual Cycle Enzymes in Vitro and in VivoJournal of Biological Chemistry201373
46Chaperone Peptides of α-Crystallin Inhibit Epithelial Cell Apoptosis, Protein Insolubilization, and Opacification in Experimental CataractsJournal of Biological Chemistry201368
47Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1Molecular Pharmacology201368
48Turnover of bone marrow‐derived cells in the irradiated mouse corneaImmunology200867
49The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activityCell Death and Disease201067
50The role of cytokines and pathogen recognition molecules in fungal keratitis – Insights from human disease and animal modelsCytokine201265