| # | Title | Journal | Year | Citations |
|---|
| 1 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial | Lancet, The | 2010 | 1,483 |
| 2 | The public health effect of economic crises and alternative policy responses in Europe: an empirical analysis | Lancet, The | 2009 | 1,132 |
| 3 | Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies | Annals of the Rheumatic Diseases | 2006 | 1,041 |
| 4 | Selenium in Human Health and Disease | Antioxidants and Redox Signaling | 2011 | 1,003 |
| 5 | Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials | American Journal of Clinical Nutrition | 2008 | 970 |
| 6 | Dissemination and publication of research findings: an updated review of related biases | Health Technology Assessment | 2010 | 706 |
| 7 | Antidepressant use and risk of adverse outcomes in older people: population based cohort study | BMJ: British Medical Journal | 2011 | 614 |
| 8 | Psychological investigation of the structure of paranoia in a non-clinical population | British Journal of Psychiatry | 2005 | 579 |
| 9 | Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review | BMJ: British Medical Journal | 2006 | 562 |
| 10 | Anticholinergic Medication Use and Cognitive Impairment in the Older Population: The Medical Research Council Cognitive Function and Ageing Study | Journal of the American Geriatrics Society | 2011 | 515 |
| 11 | Epidemiology and Clinical Features of Cryptosporidium Infection in Immunocompromised Patients | Clinical Microbiology Reviews | 2002 | 468 |
| 12 | Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis | Cmaj | 2009 | 463 |
| 13 | Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial | Lancet, The | 2011 | 444 |
| 14 | Habitual intake of flavonoid subclasses and incident hypertension in adults | American Journal of Clinical Nutrition | 2011 | 387 |
| 15 | Climate change and waterborne and vector-borne disease | Journal of Applied Microbiology | 2003 | 381 |
| 16 | Computer‐Aided Psychotherapy for Anxiety Disorders: A Meta‐Analytic Review | Cognitive Behaviour Therapy | 2009 | 373 |
| 17 | Effects of the 2008 recession on health: a first look at European data | Lancet, The | 2011 | 362 |
| 18 | Water Supply and Health | PLoS Medicine | 2010 | 344 |
| 19 | Emotion and psychosis: Links between depression, self-esteem, negative schematic beliefs and delusions and hallucinations | Schizophrenia Research | 2006 | 336 |
| 20 | The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established1–4 | Journal of Nutrition | 2011 | 328 |
| 21 | Meta-analysis of randomized controlled trials on the safety and effectiveness of earlyversusdelayed laparoscopic cholecystectomy for acute cholecystitis | British Journal of Surgery | 2010 | 322 |
| 22 | The history of African trypanosomiasis | Parasites and Vectors | 2008 | 318 |
| 23 | The zoonotic transmission of Giardia and Cryptosporidium | International Journal for Parasitology | 2005 | 316 |
| 24 | The effects of surgery on tumor growth: a century of investigations | Annals of Oncology | 2008 | 316 |
| 25 | Systematic review of multidisciplinary interventions in heart failure | Heart | 2005 | 298 |
| 26 | Measuring ideas of persecution and social reference: the Green et al. Paranoid Thought Scales (GPTS) | Psychological Medicine | 2008 | 296 |
| 27 | Does pharmacist‐led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta‐analysis | British Journal of Clinical Pharmacology | 2008 | 293 |
| 28 | Implications for neurobiological research of cognitive models of psychosis: a theoretical paper | Psychological Medicine | 2007 | 290 |
| 29 | Controlling hypertension and hypotension immediately post-stroke (CHHIPS): a randomised, placebo-controlled, double-blind pilot trial | Lancet Neurology, The | 2009 | 288 |
| 30 | Effect of medications with anti-cholinergic properties on cognitive function, delirium, physical function and mortality: a systematic review | Age and Ageing | 2014 | 269 |
| 31 | Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial | BMJ, The | 2012 | 266 |
| 32 | Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review | Health Technology Assessment | 2007 | 265 |
| 33 | Does home based medication review keep older people out of hospital? The HOMER randomised controlled trial | BMJ: British Medical Journal | 2005 | 263 |
| 34 | Associations between diet, lifestyle factors, and telomere length in women | American Journal of Clinical Nutrition | 2010 | 259 |
| 35 | Cognitive-behavioural therapy and family intervention for relapse prevention and symptom reduction in psychosis: Randomised controlled trial | British Journal of Psychiatry | 2008 | 251 |
| 36 | Selenium biofortification of high-yielding winter wheat (Triticum aestivum L.) by liquid or granular Se fertilisation | Plant and Soil | 2010 | 242 |
| 37 | Methods of assessment of selenium status in humans: a systematic review | American Journal of Clinical Nutrition | 2009 | 239 |
| 38 | Estimating the impact on health of poor reliability of drinking water interventions in developing countries | Science of the Total Environment | 2009 | 228 |
| 39 | Thiazolidinediones and Heart Failure | Diabetes Care | 2007 | 227 |
| 40 | Optimal Cost-Effectiveness Decisions: The Role of the Cost-Effectiveness Acceptability Curve (CEAC), the Cost-Effectiveness Acceptability Frontier (CEAF), and the Expected Value of Perfection Information (EVPI) | Value in Health | 2008 | 227 |
| 41 | Virtual reality study of paranoid thinking in the general population | British Journal of Psychiatry | 2008 | 226 |
| 42 | A web-based tool for adjusting costs to a specific target currency and price year | Evidence and Policy | 2010 | 226 |
| 43 | Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial | American Journal of Clinical Nutrition | 2010 | 226 |
| 44 | Meta-analyses of Adverse Effects Data Derived from Randomised Controlled Trials as Compared to Observational Studies: Methodological Overview | PLoS Medicine | 2011 | 226 |
| 45 | Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women | Proceedings of the Nutrition Society | 2006 | 225 |
| 46 | Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies | Thorax | 2011 | 224 |
| 47 | Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial | Lancet Neurology, The | 2010 | 219 |
| 48 | Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate | Autophagy | 2011 | 215 |
| 49 | Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake | Journal of Experimental Medicine | 2008 | 213 |
| 50 | Factors Affecting the Bioavailability of Soy Isoflavones in Humans after Ingestion of Physiologically Relevant Levels from Different Soy Foods | Journal of Nutrition | 2006 | 212 |
