65(top 2%)
papers
5.5K(top 1%)
citations
34(top 1%)
h-index
65(top 1%)
g-index
66
all documents
5.7K
doc citations
1.4K
citing journals

Top Articles

#TitleJournalYearCitations
1Paul Ehrlich's magic bullet concept: 100 years of progressNature Reviews Cancer20081,064
2Cloning and characterization of a G protein-activated human phosphoinositide-3 kinaseScience1995687
3Smart drugs: Tyrosine kinase inhibitors in cancer therapyCancer Cell2002474
4EGFR signal transactivation in cancer cellsBiochemical Society Transactions2003364
5Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor α-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor ReceptorCancer Research2004263
6Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) alleleCancer Research2002207
7Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivationCancer Research2002182
8Mig-6 Is a Negative Regulator of the Epidermal Growth Factor Receptor SignalBiological Chemistry2001137
9Reactive Oxygen Species Mediate Met Receptor Transactivation by G Protein-coupled Receptors and the Epidermal Growth Factor Receptor in Human Carcinoma CellsJournal of Biological Chemistry2004108
10Myc Is a Metastasis Gene for Non-Small-Cell Lung CancerPLoS ONE2009108
11The Unique C-terminal Tail of the Mitogen-activated Protein Kinase ERK5 Regulates Its Activation and Nuclear ShuttlingJournal of Biological Chemistry2005105
12HGF induces novel EGFR functions involved in resistance formation to tyrosine kinase inhibitorsOncogene2013104
13Toward the Prognostic Significance and Therapeutic Potential of HER3 Receptor Tyrosine Kinase in Human Colon CancerClinical Cancer Research2012101
14Negative Regulation of the EGFR-MAPK Cascade by Actin-MAL-Mediated Mig6/Errfi-1 InductionMolecular Cell200991
15Beyond Herceptin and GleevecCurrent Opinion in Chemical Biology200390
16Resistance to Chemotherapy Is Associated with Fibroblast Growth Factor Receptor 4 Up-RegulationClinical Cancer Research200990
17GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathwaysBiological Chemistry200589
18Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signallingJournal of Cell Science200883
19FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patientsBritish Journal of Cancer200674
20Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activatorBMC Cancer201372
21Inhibition of doxorubicin‐induced HER3‐PI3K‐AKT signalling enhances apoptosis of ovarian cancer cellsMolecular Oncology201265
22Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2‐positive cancer cells and cancer stem cellsInternational Journal of Cancer201265
23MAL/MRTF-A controls migration of non-invasive cells by upregulation of cytoskeleton-associated proteinsJournal of Cell Science201162
24The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell TumorigenesisPLoS Genetics201159
25The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cellsOncogene201057
26UV‐induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell linesInternational Journal of Cancer200956
27PTK 7 Is a Transforming Gene and Prognostic Marker for Breast Cancer and Nodal Metastasis InvolvementPLoS ONE201454
28LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody interventionOncogene201552
29FGFR4 GLY388 isotype suppresses motility of MDA-MB-231 breast cancer cells by EDG-2 gene repressionCellular Signalling200650
30Negative Regulation of HER2 Signaling by the PEST-type Protein-tyrosine Phosphatase BDP1Journal of Biological Chemistry200447
31Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 statusOncotarget201447
32The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitorsAntiviral Research201637
33Csk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activationOncogene200636
34PTP-PEST phosphatase variations in human cancerCancer Genetics and Cytogenetics200636
35RAF Kinase Activity Regulates Neuroepithelial Cell Proliferation and Neuronal Progenitor Cell Differentiation during Early Inner Ear DevelopmentPLoS ONE201036
36Protein tyrosine kinase Syk modulates EGFR signalling in human mammary epithelial cellsCellular Signalling200431
37STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasionJournal of Clinical Investigation201830
38NEK9 depletion induces catastrophic mitosis by impairment of mitotic checkpoint control and spindle dynamicsBiochemical and Biophysical Research Communications201329
39Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination TherapyNeoplasia201428
40GAS6‐expressing and self‐sustaining cancer cells in 3D spheroids activate the PDKRSKmTOR pathway for survival and drug resistanceMolecular Oncology201727
41E-cadherin Controls Bronchiolar Progenitor Cells and Onset of Preneoplastic Lesions in MiceNeoplasia201224
42Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cellsCancer Biology and Therapy201423
43Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signallingCell Cycle201221
44Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic PatientsNeoplasia201721
45MK3 controls Polycomb target gene expression via negative feedback on ERKEpigenetics and Chromatin201218
46Benzylidene‐indolinones are effective as multi‐targeted kinase inhibitor therapeutics against hepatocellular carcinomaMolecular Oncology201418
47Overexpression of Csk-binding protein contributes to renal cell carcinogenesisOncogene200917
48Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell linesMolecular Cancer201517
49Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinasesOncotarget201617
50Phosphoinositide 3-Kinase C2β Regulates RhoA and the Actin Cytoskeleton through an Interaction with DblPLoS ONE201215