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Department of Molecular Biology
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top-articles
Department of Molecular Biology
65
(top 2%)
papers
5.5K
(top 1%)
citations
34
(top 1%)
h
-index
65
(top 1%)
g
-index
66
all documents
5.7K
doc citations
1.4K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Paul Ehrlich's magic bullet concept: 100 years of progress
Nature Reviews Cancer
2008
1,064
2
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
Science
1995
687
3
Smart drugs: Tyrosine kinase inhibitors in cancer therapy
Cancer Cell
2002
474
4
EGFR signal transactivation in cancer cells
Biochemical Society Transactions
2003
364
5
Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor α-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
Cancer Research
2004
263
6
Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele
Cancer Research
2002
207
7
Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation
Cancer Research
2002
182
8
Mig-6 Is a Negative Regulator of the Epidermal Growth Factor Receptor Signal
Biological Chemistry
2001
137
9
Reactive Oxygen Species Mediate Met Receptor Transactivation by G Protein-coupled Receptors and the Epidermal Growth Factor Receptor in Human Carcinoma Cells
Journal of Biological Chemistry
2004
108
10
Myc Is a Metastasis Gene for Non-Small-Cell Lung Cancer
PLoS ONE
2009
108
11
The Unique C-terminal Tail of the Mitogen-activated Protein Kinase ERK5 Regulates Its Activation and Nuclear Shuttling
Journal of Biological Chemistry
2005
105
12
HGF induces novel EGFR functions involved in resistance formation to tyrosine kinase inhibitors
Oncogene
2013
104
13
Toward the Prognostic Significance and Therapeutic Potential of HER3 Receptor Tyrosine Kinase in Human Colon Cancer
Clinical Cancer Research
2012
101
14
Negative Regulation of the EGFR-MAPK Cascade by Actin-MAL-Mediated Mig6/Errfi-1 Induction
Molecular Cell
2009
91
15
Beyond Herceptin and Gleevec
Current Opinion in Chemical Biology
2003
90
16
Resistance to Chemotherapy Is Associated with Fibroblast Growth Factor Receptor 4 Up-Regulation
Clinical Cancer Research
2009
90
17
GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways
Biological Chemistry
2005
89
18
Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling
Journal of Cell Science
2008
83
19
FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients
British Journal of Cancer
2006
74
20
Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator
BMC Cancer
2013
72
21
Inhibition of doxorubicin‐induced HER3‐PI3K‐AKT signalling enhances apoptosis of ovarian cancer cells
Molecular Oncology
2012
65
22
Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2‐positive cancer cells and cancer stem cells
International Journal of Cancer
2012
65
23
MAL/MRTF-A controls migration of non-invasive cells by upregulation of cytoskeleton-associated proteins
Journal of Cell Science
2011
62
24
The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell Tumorigenesis
PLoS Genetics
2011
59
25
The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells
Oncogene
2010
57
26
UV‐induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell lines
International Journal of Cancer
2009
56
27
PTK 7 Is a Transforming Gene and Prognostic Marker for Breast Cancer and Nodal Metastasis Involvement
PLoS ONE
2014
54
28
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention
Oncogene
2015
52
29
FGFR4 GLY388 isotype suppresses motility of MDA-MB-231 breast cancer cells by EDG-2 gene repression
Cellular Signalling
2006
50
30
Negative Regulation of HER2 Signaling by the PEST-type Protein-tyrosine Phosphatase BDP1
Journal of Biological Chemistry
2004
47
31
Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status
Oncotarget
2014
47
32
The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors
Antiviral Research
2016
37
33
Csk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activation
Oncogene
2006
36
34
PTP-PEST phosphatase variations in human cancer
Cancer Genetics and Cytogenetics
2006
36
35
RAF Kinase Activity Regulates Neuroepithelial Cell Proliferation and Neuronal Progenitor Cell Differentiation during Early Inner Ear Development
PLoS ONE
2010
36
36
Protein tyrosine kinase Syk modulates EGFR signalling in human mammary epithelial cells
Cellular Signalling
2004
31
37
STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion
Journal of Clinical Investigation
2018
30
38
NEK9 depletion induces catastrophic mitosis by impairment of mitotic checkpoint control and spindle dynamics
Biochemical and Biophysical Research Communications
2013
29
39
Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy
Neoplasia
2014
28
40
GAS
6‐expressing and self‐sustaining cancer cells in 3D spheroids activate the
PDK
‐
RSK
‐
mTOR
pathway for survival and drug resistance
Molecular Oncology
2017
27
41
E-cadherin Controls Bronchiolar Progenitor Cells and Onset of Preneoplastic Lesions in Mice
Neoplasia
2012
24
42
Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells
Cancer Biology and Therapy
2014
23
43
Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signalling
Cell Cycle
2012
21
44
Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients
Neoplasia
2017
21
45
MK3 controls Polycomb target gene expression via negative feedback on ERK
Epigenetics and Chromatin
2012
18
46
Benzylidene‐indolinones are effective as multi‐targeted kinase inhibitor therapeutics against hepatocellular carcinoma
Molecular Oncology
2014
18
47
Overexpression of Csk-binding protein contributes to renal cell carcinogenesis
Oncogene
2009
17
48
Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines
Molecular Cancer
2015
17
49
Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases
Oncotarget
2016
17
50
Phosphoinositide 3-Kinase C2β Regulates RhoA and the Actin Cytoskeleton through an Interaction with Dbl
PLoS ONE
2012
15
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