Anti-Cancer Agents in Medicinal Chemistry

7.0(top 2%)

impact factor

192(top 50%)

papers

11.1K(top 20%)

citations

59(top 10%)

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7.3(top 2%)

impact factor

207

all documents

11.9K

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99(top 10%)

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Top Articles

#	Title	Journal	Year	Citations
1	Mechanism of Action of Antitumor Drugs that Interact with Microtubules and Tubulin	Anti-Cancer Agents in Medicinal Chemistry	2012	597
2	Etoposide, Topoisomerase II and Cancer	Anti-Cancer Agents in Medicinal Chemistry	2005	416
3	Synthetic and Natural Coumarins as Cytotoxic Agents	Anti-Cancer Agents in Medicinal Chemistry	2005	384
4	Targeting Microtubules for Cancer Chemotherapy	Anti-Cancer Agents in Medicinal Chemistry	2005	374
5	Medicinal Properties of Neem Leaves: A Review	Anti-Cancer Agents in Medicinal Chemistry	2005	347
6	Aminophosphonic Acids of Potential Medical Importance	Anti-Cancer Agents in Medicinal Chemistry	2001	309
7	Anti-Cancer Potential of Sesquiterpene Lactones: Bioactivity and Molecular Mechanisms	Anti-Cancer Agents in Medicinal Chemistry	2005	309
8	Naphthalimides as Anticancer Agents: Synthesis and Biological Activity	Anti-Cancer Agents in Medicinal Chemistry	2001	221
9	The Interaction of Histone Deacetylase Inhibitors and DNA Methyltransferase Inhibitors in the Treatment of Human Cancer Cells	Anti-Cancer Agents in Medicinal Chemistry	2003	201
10	Lamellarins, from A to Z: A Family of Anticancer Marine Pyrrole Alkaloids	Anti-Cancer Agents in Medicinal Chemistry	2004	179
11	Flavonoids as Anticancer Agents: Structure-Activity Relationship Study	Anti-Cancer Agents in Medicinal Chemistry	2002	178
12	Apoptosis Induced by Topoisomerase Inhibitors	Anti-Cancer Agents in Medicinal Chemistry	2003	176
13	Porphyrins in Photodynamic Therapy - A Search for Ideal Photosensitizers	Anti-Cancer Agents in Medicinal Chemistry	2002	171
14	Porphyrin-based Sensitizers in the Detection and Treatment of Cancer: Recent Progress	Anti-Cancer Agents in Medicinal Chemistry	2001	168
15	Vascular Endothelial Cell Growth Factor (VEGF), An Emerging Target for Cancer Chemotherapy	Anti-Cancer Agents in Medicinal Chemistry	2003	168
16	The Biology and Medicinal Chemistry of Epothilones	Anti-Cancer Agents in Medicinal Chemistry	2012	168
17	Cisplatin Is a DNA-Damaging Antitumour Compound Triggering Multifactorial Biochemical Responses in Cancer Cells: Importance of Apoptotic Pathways	Anti-Cancer Agents in Medicinal Chemistry	2005	163
18	Recent Progress in the Development of Anticancer Agents	Anti-Cancer Agents in Medicinal Chemistry	2002	152
19	Dications That Target the DNA Minor Groove: Compound Design and Preparation, DNA Interactions, Cellular Distribution and Biological Activity	Anti-Cancer Agents in Medicinal Chemistry	2005	144
20	On the Selectivity of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Formation	Anti-Cancer Agents in Medicinal Chemistry	2004	139
21	Anthracyclines: Selected New Developments	Anti-Cancer Agents in Medicinal Chemistry	2001	133
22	The Molecular Mechanisms for the Antitumorigenic Effect of Curcumin	Anti-Cancer Agents in Medicinal Chemistry	2002	133
23	Novel Aspects of Natural and Modified Vinca Alkaloids	Anti-Cancer Agents in Medicinal Chemistry	2012	130
24	Resveratrol and Cancer: Chemoprevention, Apoptosis, and Chemoimmunosensitizing Activities	Anti-Cancer Agents in Medicinal Chemistry	2003	129
25	Chemoresistance in Non-Small Cell Lung Cancer	Anti-Cancer Agents in Medicinal Chemistry	2005	129
26	Cytotoxic and Antitumor Potentialities of Aporphinoid Alkaloids	Anti-Cancer Agents in Medicinal Chemistry	2005	128
27	The Quinolone Family: From Antibacterial to Anticancer Agents	Anti-Cancer Agents in Medicinal Chemistry	2003	118
28	Lycopene: A Review of Its Potential as an Anticancer Agent	Anti-Cancer Agents in Medicinal Chemistry	2005	117
29	Signal Transduction Pathways of Taxanes-Induced Apoptosis	Anti-Cancer Agents in Medicinal Chemistry	2003	112
30	Green Tea Catechins as Novel Antitumor and Antiangiogenic Compounds	Anti-Cancer Agents in Medicinal Chemistry	2002	110
31	Extending Natures Leads: The Anticancer Agent Ellipticine	Anti-Cancer Agents in Medicinal Chemistry	2004	106
32	Programmable DNA Binding Oligomers for Control of Transcription	Anti-Cancer Agents in Medicinal Chemistry	2005	104
33	Inhibition of PI3K/Akt Signaling: An Emerging Paradigm for Targeted Cancer Therapy	Anti-Cancer Agents in Medicinal Chemistry	2005	103
34	Cisplatin Resistance and Transcription Factors	Anti-Cancer Agents in Medicinal Chemistry	2005	101
35	Cytotoxic Anticancer Candidates from Natural Resources	Anti-Cancer Agents in Medicinal Chemistry	2002	96
36	The Prodrugs of 5-Fluorouracil	Anti-Cancer Agents in Medicinal Chemistry	2002	95
37	Drugs that Inhibit Tubulin Polymerization: The Particular Case of Podophyllotoxin and Analogues	Anti-Cancer Agents in Medicinal Chemistry	2012	95
38	Cardiac Toxicity of Antineoplastic Anthracyclines	Anti-Cancer Agents in Medicinal Chemistry	2003	95
39	DNA Topoisomerases as Anticancer Drug Targets: From the Laboratory to the Clinic	Anti-Cancer Agents in Medicinal Chemistry	2001	89
40	Synthesis, Proton-Affinity and Anti-Cancer Properties of the Prodigiosin-Group Natural Products	Anti-Cancer Agents in Medicinal Chemistry	2001	87
41	Camptothecins and Topoisomerase I; A Foot in the Door. Targeting the Genome Beyond Topoisomerase I with Camptothecins and Novel Anticancer Drugs; Importance of DNA Replication, Repair and Cell Cycle Checkpoints	Anti-Cancer Agents in Medicinal Chemistry	2004	87
42	Novel Concepts in the Development of Platinum Antitumor Drugs	Anti-Cancer Agents in Medicinal Chemistry	2002	87
43	Identification and Characterization of the Binding Sites of P-Glycoprotein for Multidrug Resistance-Related Drugs and Modulators	Anti-Cancer Agents in Medicinal Chemistry	2004	85
44	Soy Saponins and the Anticancer Effects of Soybeans and Soy-Based Foods	Anti-Cancer Agents in Medicinal Chemistry	2004	85
45	Membrane Targeted Anticancer Drugs: Potent Inducers of Apoptosis and Putative Radiosensitisers	Anti-Cancer Agents in Medicinal Chemistry	2003	84
46	Multi-Nuclear Platinum Drugs: A New Paradigm in Chemotherapy	Anti-Cancer Agents in Medicinal Chemistry	2005	84
47	Recent Developments in the Design, Synthesis and Structure-Activity Relationship Studies of Pyrrolo[2,1-c][1,4]benzodiazepines as DNA-Interactive Antitumour Antibiotics	Anti-Cancer Agents in Medicinal Chemistry	2002	82
48	Cytotoxic Activity of Styryl Lactones and their Derivatives	Anti-Cancer Agents in Medicinal Chemistry	2001	81
49	Sesquiterpenes: Natural Products That Decrease Cancer Growth	Anti-Cancer Agents in Medicinal Chemistry	2005	79
50	Peptides as Carrier for Tumor Diagnosis and Treatment	Anti-Cancer Agents in Medicinal Chemistry	2001	78

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