4.0(top 10%)
impact factor
990(top 20%)
papers
10.4K(top 20%)
citations
37(top 20%)
h-index
4.1(top 10%)
impact factor
1.3K
all documents
13.4K
doc citations
59(top 20%)
g-index

Top Articles

#TitleJournalYearCitations
1TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cellsLife Science Alliance2020597
2Detecting sequence signals in targeting peptides using deep learningLife Science Alliance2019561
3Dynamic m6A methylation facilitates mRNA triaging to stress granulesLife Science Alliance2018136
4m6A-mRNA methylation regulates cardiac gene expression and cellular growthLife Science Alliance2019109
5Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicityLife Science Alliance201888
6Caspase-1 interdomain linker cleavage is required for pyroptosisLife Science Alliance202082
7A network of human functional gene interactions from knockout fitness screens in cancer cellsLife Science Alliance201981
8A FIJI macro for quantifying pattern in extracellular matrixLife Science Alliance202175
9Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancerLife Science Alliance202175
10Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4Life Science Alliance201874
11USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylationLife Science Alliance202072
12The histone chaperone FACT modulates nucleosome structure by tethering its componentsLife Science Alliance201868
13Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoidsLife Science Alliance202167
14Evaluation of colorectal cancer subtypes and cell lines using deep learningLife Science Alliance201965
15Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophagesLife Science Alliance202164
16Cx3cr1-deficient microglia exhibit a premature aging transcriptomeLife Science Alliance201964
17Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMDLife Science Alliance202064
18A serum proteome signature to predict mortality in severe COVID-19 patientsLife Science Alliance202162
19MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapyLife Science Alliance201961
201,6-hexanediol rapidly immobilizes and condenses chromatin in living human cellsLife Science Alliance202159
21The expansion in lymphoid organs of IL-4+BATF+T follicular helper cells is linked to IgG4 class switching in vivoLife Science Alliance201858
22Serine catabolism is essential to maintain mitochondrial respiration in mammalian cellsLife Science Alliance201857
23Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasomeLife Science Alliance201856
24Noncoding AUG circRNAs constitute an abundant and conserved subclass of circlesLife Science Alliance201956
25Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progressionLife Science Alliance202156
26Co-existing feedback loops generate tissue-specific circadian rhythmsLife Science Alliance201855
27The m6A pathway protects the transcriptome integrity by restricting RNA chimera formation in plantsLife Science Alliance201953
28Robust production of uniform human cerebral organoids from pluripotent stem cellsLife Science Alliance202052
29Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkersLife Science Alliance201851
30Silica-based solid-phase extraction of cross-linked nucleic acid–bound proteinsLife Science Alliance201849
31Topological in vitro loading of the budding yeast cohesin ring onto DNALife Science Alliance201849
32Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathyLife Science Alliance201949
33The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical mannerLife Science Alliance201949
34CRISPR-induced double-strand breaks trigger recombination between homologous chromosome armsLife Science Alliance201948
35Stromal fibroblasts induce metastatic tumor cell clusters via epithelial–mesenchymal plasticityLife Science Alliance201948
36SARS-CoV-2 infection induces protective immunity and limits transmission in Syrian hamstersLife Science Alliance202147
37DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophagesLife Science Alliance201947
38BACE2 distribution in major brain cell types and identification of novel substratesLife Science Alliance201846
39Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapsesLife Science Alliance201846
40Re-annotation of eightDrosophilagenomesLife Science Alliance201846
41An integrative machine learning approach for prediction of toxicity-related drug safetyLife Science Alliance201844
42CARM1 methylates MED12 to regulate its RNA-binding abilityLife Science Alliance201843
43Refining the adipose progenitor cell landscape in healthy and obese visceral adipose tissue using single-cell gene expression profilingLife Science Alliance201943
44Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolutionLife Science Alliance202043
45SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degenerationLife Science Alliance202042
46Optimized ChIP-seq method facilitates transcription factor profiling in human tumorsLife Science Alliance201941
47MBNL1 alternative splicing isoforms play opposing roles in cancerLife Science Alliance201841
48Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO miceLife Science Alliance201941
49PISDis a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changesLife Science Alliance201941
50Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesisLife Science Alliance201941