Current Drug Targets Immune, Endocrine and Metabolic Disorders

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Top Articles

#	Title	Journal	Year	Citations
1	Dual Roles of Adiponectin / Acrp30 In Vivo as an Anti-Diabetic and Anti- Atherogenic Adipokine	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	127
2	Protein-Tyrosine Phosphatase 1B (PTP1B): A Novel Therapeutic Target for Type 2 Diabetes Mellitus, Obesity and Related States of Insulin Resistance	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2001	123
3	Regulation of the Steroidogenic Acute Regulatory Protein Expression: Functional and Physiological Consequences	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	118
4	Skin Photoprotection by Green Tea: Antioxidant and Immunomodulatory Effects	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	109
5	Insulin Regulation of PEPCK Gene Expression: A Model for Rapid and Reversible Modulation	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	98
6	Role of FXR in Regulating Bile Acid Homeostasis and Relevance for Human Diseases	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	96
7	CXCR3-binding Chemokines: Novel Multifunctional Therapeutic Targets	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	96
8	DI-2-Ethylhexyl Phthalate and Endocrine Disruption: A Review	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	88
9	Caspases as Drug Targets in Ischemic Organ Injury	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	88
10	Stearoyl-CoA Desaturase-1 and the Metabolic Syndrome	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	85
11	Tissue-Specific Glucocorticoid Reactivating Enzyme, 11β-Hydroxysteoid Dehydrogenase Type 1 (11β-HSD1) - A Promising Drug Target for the Treatment of Metabolic Syndrome	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	85
12	Activins, Myostatin and Related TGF-β Family Members as Novel Therapeutic Targets for Endocrine, Metabolic and Immune Disorders	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	83
13	Cytomegalovirus Infection in Immunocompetent and Immunocompromised Individuals - A ReviewCytomegalovirus Infection in Immunocompetent and Immunocompromised Individuals - A Review	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2001	80
14	Physiological Roles of Glycogen Synthase Kinase-3: Potential as a Therapeutic Target for Diabetes and Other Disorders	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	75
15	Myocardial Insulin Resistance and Cardiac Complications of Diabetes	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	69
16	Chemokine-Chemokine Receptor Network in Immune Cell Trafficking	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	67
17	Amino Acid Transporter ATB0,+ as a Delivery System for Drugs and Prodrugs	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	67
18	Estrogens and Colorectal Cancer	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2001	63
19	Biosynthetic Pathways of Plastid-Derived Organelles as Potential Drug Targets Against Parasitic Apicomplexa	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	55
20	Reduction of Hepatic Glucose Production as a Therapeutic Target in the Treatment of Diabetes	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	55
21	Cytomegalovirus Infection in Immunocompetent and Immunocompromised Individuals - A ReviewCytomegalovirus Infection in Immunocompetent and Immunocompromised Individuals - A Review	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2001	54
22	Targeting the AMP-Activated Protein Kinase for the Treatment of Type 2 Diabetes	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2002	52
23	Effects of Endocrine Disruptors on Developmental and Reproductive Functions	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	50
24	Cytomegalovirus infection in immunocompetent and immunocompromised individuals--a review	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2001	50
25	Vaccination Against Leishmania Infections	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2002	48
26	CD26 / Dipeptidyl Peptidase IV: A Regulator of Immune Function and a Potential Molecular Target for Therapy	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	46
27	Unfolding the Pathophysiological Role of Bioactive Lysophospholipids	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	44
28	Prospects for A Schistosome Vaccine	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2002	42
29	The PAX8 / PPARγ Fusion Oncogene as a Potential Therapeutic Target in Follicular Thyroid Carcinoma	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	41
30	Therapeutic Potential of Glycolipid Ligands for Natural Killer (NK) T Cells in the Suppression of Autoimmune Diseases	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	39
31	Failure of Immune Homeostasis - The Consequences of Under and Over Reactivity	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	39
32	Determination of Binding Constant of DNA-binding Drug to Target DNA by Surface Plasmon Resonance Biosensor Technology	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	39
33	Studies on Human Neutrophil Biological Functions by Means of Formylpeptide Receptor Agonists and Antagonists	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	37
34	Melatonin Role in Experimental Arthritis	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	37
35	Redifferentiation Therapy in Advanced Thyroid Cancer	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	37
36	Drug-Induced Aseptic Meningitis	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	36
37	Boosting Interleukin-10 Production: Therapeutic Effects and Mechanisms	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	36
38	Angiogenesis and Angiogenesis Inhibitors: a New Potential Anticancer Therapeutic Strategy	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2001	35
39	Metformin and its Liver Targets in the Treatment of Type 2 Diabetes	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	35
40	Evidences for iNOS Expression and Nitric Oxide Production in the Human Macrophages	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	35
41	Hormonal Effects on Drug Metabolism Through the CYP System: Perspectives on Their Potential Significance in the Era of Pharmacogenomics	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	33
42	Unfolding the pathophysiological role of bioactive lysophospholipids	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	33
43	AKT: A Potential Target for Thyroid Cancer Therapy	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	32
44	The Pathobiology of Osteoarthritis and the Rationale for Using the Chondroitin Sulfate for its Treatment	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	31
45	Augmenting T Helper Cell Immunity in Cancer	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	30
46	Therapeutic Potential of the Mammalian Pyruvate Dehydrogenase Kinases in the Prevention of Hyperglycaemia	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2002	30
47	Controlled Modulation of Inflammatory, Stress and Apoptotic Responses in Macrophages	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	29
48	The Sodium-Iodide Symporter	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2004	29
49	Unfolding the Pathophysiological Role of Bioactive Lysophospholipids	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2003	28
50	Signal Transducer and Activator of Transcription 5 (STAT5), a Crucial Regulator of Immune and Cancer Cells	Current Drug Targets Immune, Endocrine and Metabolic Disorders	2005	28

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