| 1 | Heterogeneous single-atom catalysis | Nature Reviews Chemistry | 2018 | 3,791 |
| 2 | Earth-abundant catalysts for electrochemical and photoelectrochemical water splitting | Nature Reviews Chemistry | 2017 | 3,143 |
| 3 | The merger of transition metal and photocatalysis | Nature Reviews Chemistry | 2017 | 2,033 |
| 4 | Chemical recycling of waste plastics for new materials production | Nature Reviews Chemistry | 2017 | 1,773 |
| 5 | Prospects of organic electrode materials for practical lithium batteries | Nature Reviews Chemistry | 2020 | 1,203 |
| 6 | MXene chemistry, electrochemistry and energy storage applications | Nature Reviews Chemistry | 2022 | 1,151 |
| 7 | Electrochemical synthesis of hydrogen peroxide from water and oxygen | Nature Reviews Chemistry | 2019 | 989 |
| 8 | Towards the sustainable discovery and development of new antibiotics | Nature Reviews Chemistry | 2021 | 946 |
| 9 | Synthesis and chemistry of elemental 2D materials | Nature Reviews Chemistry | 2017 | 860 |
| 10 | Haemostatic materials for wound healing applications | Nature Reviews Chemistry | 2021 | 829 |
| 11 | Analysis of aptamer discovery and technology | Nature Reviews Chemistry | 2017 | 808 |
| 12 | Earth-abundant transition metal catalysts for alkene hydrosilylation and hydroboration | Nature Reviews Chemistry | 2018 | 788 |
| 13 | Chiral molecules and the electron spin | Nature Reviews Chemistry | 2019 | 778 |
| 14 | Low-dimensional catalysts for hydrogen evolution and CO2 reduction | Nature Reviews Chemistry | 2018 | 776 |
| 15 | Biomimetic peptide self-assembly for functional materials | Nature Reviews Chemistry | 2020 | 742 |
| 16 | Hexafluoroisopropanol as a highly versatile solvent | Nature Reviews Chemistry | 2017 | 736 |
| 17 | Late-stage C–H functionalization offers new opportunities in drug discovery | Nature Reviews Chemistry | 2021 | 706 |
| 18 | The added value of small-molecule chirality in technological applications | Nature Reviews Chemistry | 2017 | 693 |
| 19 | Phase engineering of nanomaterials | Nature Reviews Chemistry | 2020 | 690 |
| 20 | The role of chemical design in the performance of organic semiconductors | Nature Reviews Chemistry | 2020 | 674 |
| 21 | The concept of active site in heterogeneous catalysis | Nature Reviews Chemistry | 2022 | 634 |
| 22 | Recent advances in the chemistry and applications of N-heterocyclic carbenes | Nature Reviews Chemistry | 2021 | 627 |
| 23 | Synthesis, structures and applications of electron-rich polyoxometalates | Nature Reviews Chemistry | 2018 | 625 |
| 24 | Physical unclonable functions generated through chemical methods for anti-counterfeiting | Nature Reviews Chemistry | 2017 | 605 |
| 25 | Designing catalysts for olefin polymerization and copolymerization: beyond electronic and steric tuning | Nature Reviews Chemistry | 2018 | 588 |
| 26 | Heteroaryl azo dyes as molecular photoswitches | Nature Reviews Chemistry | 2019 | 578 |
| 27 | New avenues for the large-scale harvesting of blue energy | Nature Reviews Chemistry | 2017 | 567 |
| 28 | Supramolecular polymerization through kinetic pathway control and living chain growth | Nature Reviews Chemistry | 2019 | 551 |
| 29 | Highlights and challenges in the selective reduction of carbon dioxide to methanol | Nature Reviews Chemistry | 2021 | 535 |
| 30 | The medicinal chemistry of ferrocene and its derivatives | Nature Reviews Chemistry | 2017 | 534 |
| 31 | Circularly polarized lanthanide luminescence for advanced security inks | Nature Reviews Chemistry | 2020 | 527 |
| 32 | Metal oxide redox chemistry for chemical looping processes | Nature Reviews Chemistry | 2018 | 512 |
| 33 | Metals to combat antimicrobial resistance | Nature Reviews Chemistry | 2023 | 510 |
| 34 | The ins and outs of microorganism–electrode electron transfer reactions | Nature Reviews Chemistry | 2017 | 485 |
| 35 | Metal halide perovskite tandem and multiple-junction photovoltaics | Nature Reviews Chemistry | 2017 | 482 |
| 36 | A unified view on catalytic conversion of biomass and waste plastics | Nature Reviews Chemistry | 2022 | 472 |
| 37 | Exploiting chemistry and molecular systems for quantum information science | Nature Reviews Chemistry | 2020 | 471 |
| 38 | Wearable chemical sensors for biomarker discovery in the omics era | Nature Reviews Chemistry | 2022 | 468 |
| 39 | Clarifying the four core effects of high-entropy materials | Nature Reviews Chemistry | 2024 | 466 |
| 40 | Semiconducting quantum dots for artificial photosynthesis | Nature Reviews Chemistry | 2018 | 457 |
| 41 | Contemporary approaches to site-selective protein modification | Nature Reviews Chemistry | 2019 | 457 |
| 42 | Metal–organic cages for molecular separations | Nature Reviews Chemistry | 2021 | 444 |
| 43 | From plasmon-enhanced molecular spectroscopy to plasmon-mediated chemical reactions | Nature Reviews Chemistry | 2018 | 437 |
| 44 | Hierarchically oriented organization in supramolecular peptide crystals | Nature Reviews Chemistry | 2019 | 434 |
| 45 | Quadruplex nucleic acids as targets for anticancer therapeutics | Nature Reviews Chemistry | 2017 | 430 |
| 46 | Well-defined nickel and palladium precatalysts for cross-coupling | Nature Reviews Chemistry | 2017 | 418 |
| 47 | Strategies for binding multiple guests in metal–organic cages | Nature Reviews Chemistry | 2019 | 417 |
| 48 | Advances and opportunities in the exciting world of azobenzenes | Nature Reviews Chemistry | 2021 | 416 |
| 49 | Water at charged interfaces | Nature Reviews Chemistry | 2021 | 412 |
| 50 | Surface-enhanced Raman spectroscopy for in vivo biosensing | Nature Reviews Chemistry | 2017 | 401 |
