2.0(top 20%)
impact factor
570(top 50%)
papers
28.4K(top 10%)
citations
84(top 10%)
h-index
2.3(top 20%)
impact factor
617
all documents
30.4K
doc citations
145(top 5%)
g-index

Top Articles

#TitleJournalYearCitations
1Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic TherapiesGenes and Cancer20111,074
2Hypoxia-Induced Angiogenesis: Good and EvilGenes and Cancer2011893
3Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of TumorigenesisGenes and Cancer2011751
4Ras in Cancer and Developmental DiseasesGenes and Cancer2011714
5RAS Interaction with PI3K: More Than Just Another Effector PathwayGenes and Cancer2011580
6DNA Methylation: Superior or Subordinate in the Epigenetic Hierarchy?Genes and Cancer2011564
7The ERK Cascade: Distinct Functions within Various Subcellular OrganellesGenes and Cancer2011413
8Role of p38 MAP Kinase Signal Transduction in Solid TumorsGenes and Cancer2013409
9Li-Fraumeni SyndromeGenes and Cancer2011364
10PTEN Tumor Suppressor Network in PI3K-Akt Pathway ControlGenes and Cancer2010347
11Raf Family Kinases: Old Dogs Have Learned New TricksGenes and Cancer2011322
12Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival PatternsGenes and Cancer2010283
13Therapeutic Strategies for Targeting Ras ProteinsGenes and Cancer2011282
14The Dual Role of Sirtuins in CancerGenes and Cancer2011281
15Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular CancerGenes and Cancer2013277
16MYC and Breast CancerGenes and Cancer2010275
17The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapyGenes and Cancer2018272
18JNK-signaling: A multiplexing hub in programmed cell deathGenes and Cancer2017271
19Mitogen-Activated Protein Kinases and Their Role in Radiation ResponseGenes and Cancer2013256
20Quantitative Methods for Assessing Drug SynergismGenes and Cancer2011251
21Targeting MYC Expression through G-QuadruplexesGenes and Cancer2010250
22MYC and Prostate CancerGenes and Cancer2010245
23GATA Transcription Factors and CancerGenes and Cancer2010244
24Mechanisms of Resistance to Anti-Angiogenic Therapy and Development of Third-Generation Anti-Angiogenic Drug CandidatesGenes and Cancer2010223
25The Unfolded Protein Response, Degradation from the Endoplasmic Reticulum, and CancerGenes and Cancer2010220
26Colorectal Neoplasia Differentially Expressed (CRNDE), a Novel Gene with Elevated Expression in Colorectal Adenomas and AdenocarcinomasGenes and Cancer2011219
27Functional Specificity of Ras Isoforms: So Similar but So DifferentGenes and Cancer2011218
28Myc Roles in Hematopoiesis and LeukemiaGenes and Cancer2010217
29Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in Triple-Negative Breast Cancer and Other Primary Human Tumor TypesGenes and Cancer2010216
30The Role of p53 in Metabolic RegulationGenes and Cancer2011210
31Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)Genes and Cancer2010206
32Genetic Abnormalities and Challenges in the Treatment of Acute Myeloid LeukemiaGenes and Cancer2011200
33Trop2 and its overexpression in cancers: regulation and clinical/ therapeutic implicationsGenes and Cancer2014200
34The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and TherapyGenes and Cancer2010189
35The Roles of SIRT1 in CancerGenes and Cancer2013188
36Cyclins and Cell Cycle Control in Cancer and DiseaseGenes and Cancer2012180
37JAK/STAT Pathways in Cytokine Signaling and Myeloproliferative Disorders: Approaches for Targeted TherapiesGenes and Cancer2010179
38Targeting Histone Demethylases: A New Avenue for the Fight against CancerGenes and Cancer2011177
39Molecular Mechanisms of Tumor AngiogenesisGenes and Cancer2011170
40Lymphangiogenesis and CancerGenes and Cancer2011165
41MicroRNA in Cancer: The Involvement of Aberrant MicroRNA Biogenesis Regulatory PathwaysGenes and Cancer2010157
42Inflammation and p53: A Tale of Two StressesGenes and Cancer2011156
43Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer CellsGenes and Cancer2011156
44CDK4: A Key Player in the Cell Cycle, Development, and CancerGenes and Cancer2012152
45Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 ActivityGenes and Cancer2012152
46Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase InhibitorsGenes and Cancer2010149
47p53 Isoforms: An Intracellular Microprocessor?Genes and Cancer2011141
48Histone Modifiers in Cancer: Friends or Foes?Genes and Cancer2011139
49Therapeutic Targeting of MycGenes and Cancer2010135
50SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and ProgressionGenes and Cancer2010134