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Top Articles

1Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndromeScience Immunology2020851
2TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytesScience Immunology2020811
3The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patientsScience Immunology2020772
4Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patientsScience Immunology2020714
5Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19Science Immunology2020689
6Comprehensive mapping of immune perturbations associated with severe COVID-19Science Immunology2020677
7Structure and function of the immune system in the spleenScience Immunology2019592
8Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patientsScience Immunology2020561
9Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patientsScience Immunology2016560
10Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccinationScience Immunology2021556
11Gasdermin D plays a vital role in the generation of neutrophil extracellular trapsScience Immunology2018486
12ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathwaysScience Immunology2016464
13SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipientsScience Immunology2021455
14Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular trapsScience Immunology2018425
15The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemnessScience Immunology2016415
16Location, location, location: Tissue resident memory T cells in mice and humansScience Immunology2019406
17Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcomeScience Immunology2020404
18Revisiting IL-2: Biology and therapeutic prospectsScience Immunology2018398
19TLR7 escapes X chromosome inactivation in immune cellsScience Immunology2018395
20Immune responses at the maternal-fetal interfaceScience Immunology2019380
21An immune clock of human pregnancyScience Immunology2017371
22Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsisScience Immunology2018369
23Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deathsScience Immunology2021357
24Neutrophils: New insights and open questionsScience Immunology2018348
25Natural killer cell immunotypes related to COVID-19 disease severityScience Immunology2020344
26Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipientsScience Immunology2022337
27Gasdermin E–mediated target cell pyroptosis by CAR T cells triggers cytokine release syndromeScience Immunology2020314
28Inhibition of Bruton tyrosine kinase in patients with severe COVID-19Science Immunology2020304
29A melanin-mediated cancer immunotherapy patchScience Immunology2017300
30Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomicsScience Immunology2020296
31Targeted deletion of PD-1 in myeloid cells induces antitumor immunityScience Immunology2020287
32X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19Science Immunology2021267
33Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves T H 1/T FH fate bifurcation in malariaScience Immunology2017258
34Recovery from the Middle East respiratory syndrome is associated with antibody and T cell responsesScience Immunology2017252
35Dynamics of influenza-induced lung-resident memory T cells underlie waning heterosubtypic immunityScience Immunology2017250
36Tumor immune evasion arises through loss of TNF sensitivityScience Immunology2018244
37Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescenceScience Immunology2020244
38Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunityScience Immunology2019242
39SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protectionScience Immunology2020240
40Platelets subvert T cell immunity against cancer via GARP-TGFβ axisScience Immunology2017237
41Tumor-derived exosomes modulate PD-L1 expression in monocytesScience Immunology2017236
42Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritisScience Immunology2017228
43Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patientsScience Immunology2021223
44Vaccination before or after SARS-CoV-2 infection leads to robust humoral response and antibodies that effectively neutralize variantsScience Immunology2022220
45Type I interferons instigate fetal demise after Zika virus infectionScience Immunology2018212
46Resident memory T cells in the skin mediate durable immunity to melanomaScience Immunology2017209
47Precursors of human CD4 + cytotoxic T lymphocytes identified by single-cell transcriptome analysisScience Immunology2018209
48Resident memory CD8 + T cells in the upper respiratory tract prevent pulmonary influenza virus infectionScience Immunology2017205
49Low CD21 expression defines a population of recent germinal center graduates primed for plasma cell differentiationScience Immunology2017203
50Generation and persistence of human tissue-resident memory T cells in lung transplantationScience Immunology2019203