# | Title | Journal | Year | Citations |
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1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
2 | Biological properties of extracellular vesicles and their physiological functions | Journal of Extracellular Vesicles | 2015 | 3,973 |
3 | Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles | Journal of Extracellular Vesicles | 2014 | 2,110 |
4 | Routes and mechanisms of extracellular vesicle uptake | Journal of Extracellular Vesicles | 2014 | 1,874 |
5 | Standardization of sample collection, isolation and analysis methods in extracellular vesicle research | Journal of Extracellular Vesicles | 2013 | 1,837 |
6 | Optimized exosome isolation protocol for cell culture supernatant and human plasma | Journal of Extracellular Vesicles | 2015 | 1,204 |
7 | Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting | Journal of Extracellular Vesicles | 2015 | 1,077 |
8 | Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper | Journal of Extracellular Vesicles | 2015 | 1,020 |
9 | Single‐step isolation of extracellular vesicles by size‐exclusion chromatography | Journal of Extracellular Vesicles | 2014 | 820 |
10 | Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes | Journal of Extracellular Vesicles | 2013 | 774 |
11 | The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling | Journal of Extracellular Vesicles | 2014 | 725 |
12 | As we wait: coping with an imperfect nomenclature for extracellular vesicles | Journal of Extracellular Vesicles | 2013 | 718 |
13 | Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey | Journal of Extracellular Vesicles | 2016 | 703 |
14 | Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell‐free blood | Journal of Extracellular Vesicles | 2014 | 642 |
15 | Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper | Journal of Extracellular Vesicles | 2017 | 561 |
16 | How pure are your vesicles? | Journal of Extracellular Vesicles | 2013 | 547 |
17 | High‐resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources | Journal of Extracellular Vesicles | 2016 | 503 |
18 | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell‐derived exosomes | Journal of Extracellular Vesicles | 2012 | 493 |
19 | Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation | Journal of Extracellular Vesicles | 2012 | 466 |
20 | Extracellular vesicle sizing and enumeration by nanoparticle tracking analysis | Journal of Extracellular Vesicles | 2013 | 426 |
21 | Macrophage‐dependent clearance of systemically administered B16BL6‐derived exosomes from the blood circulation in mice | Journal of Extracellular Vesicles | 2015 | 410 |
22 | EVpedia: an integrated database of high‐throughput data for systemic analyses of extracellular vesicles | Journal of Extracellular Vesicles | 2013 | 401 |
23 | Defining mesenchymal stromal cell (MSC)‐derived small extracellular vesicles for therapeutic applications | Journal of Extracellular Vesicles | 2019 | 400 |
24 | High‐speed centrifugation induces aggregation of extracellular vesicles | Journal of Extracellular Vesicles | 2015 | 390 |
25 | Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature | Journal of Extracellular Vesicles | 2019 | 377 |
26 | Inhibiting extracellular vesicles formation and release: a review of EV inhibitors | Journal of Extracellular Vesicles | 2020 | 375 |
27 | Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells | Journal of Extracellular Vesicles | 2017 | 357 |
28 | Importance of exosome depletion protocols to eliminate functional and RNA‐containing extracellular vesicles from fetal bovine serum | Journal of Extracellular Vesicles | 2014 | 353 |
29 | Quality and efficiency assessment of six extracellular vesicle isolation methods by nano‐flow cytometry | Journal of Extracellular Vesicles | 2020 | 353 |
30 | The influence of rotor type and centrifugation time on the yield and purity of extracellular vesicles | Journal of Extracellular Vesicles | 2014 | 343 |
31 | Comparative marker analysis of extracellular vesicles in different human cancer types | Journal of Extracellular Vesicles | 2013 | 321 |
32 | Extracellular vesicle measurements with nanoparticle tracking analysis – An accuracy and repeatability comparison between NanoSight NS300 and ZetaView | Journal of Extracellular Vesicles | 2019 | 318 |
33 | ExoCarta as a resource for exosomal research | Journal of Extracellular Vesicles | 2012 | 314 |
34 | A novel community driven software for functional enrichment analysis of extracellular vesicles data | Journal of Extracellular Vesicles | 2017 | 314 |
35 | Exosomal miRNAs as cancer biomarkers and therapeutic targets | Journal of Extracellular Vesicles | 2016 | 305 |
36 | Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer | Journal of Extracellular Vesicles | 2015 | 287 |
37 | Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma | Journal of Extracellular Vesicles | 2018 | 286 |
38 | Display of GPI‐anchored anti‐EGFR nanobodies on extracellular vesicles promotes tumour cell targeting | Journal of Extracellular Vesicles | 2016 | 284 |
39 | Ginger‐derived nanoparticles protect against alcohol‐induced liver damage | Journal of Extracellular Vesicles | 2015 | 277 |
40 | Co‐isolation of extracellular vesicles and high‐density lipoproteins using density gradient ultracentrifugation | Journal of Extracellular Vesicles | 2014 | 271 |
41 | Comparative analysis of discrete exosome fractions obtained by differential centrifugation | Journal of Extracellular Vesicles | 2014 | 262 |
42 | Comparison of small extracellular vesicles isolated from plasma by ultracentrifugation or size‐exclusion chromatography: yield, purity and functional potential | Journal of Extracellular Vesicles | 2019 | 254 |
43 | Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer | Journal of Extracellular Vesicles | 2016 | 249 |
44 | MIFlowCyt‐EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments | Journal of Extracellular Vesicles | 2020 | 243 |
45 | Exosomal proteins as potential diagnostic markers in advanced non‐small cell lung carcinoma | Journal of Extracellular Vesicles | 2015 | 242 |
46 | Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content | Journal of Extracellular Vesicles | 2015 | 240 |
47 | Physical exercise induces rapid release of small extracellular vesicles into the circulation | Journal of Extracellular Vesicles | 2015 | 238 |
48 | Isolation and characterization of platelet‐derived extracellular vesicles | Journal of Extracellular Vesicles | 2014 | 237 |
49 | Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane | Journal of Extracellular Vesicles | 2017 | 237 |
50 | Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons | Journal of Extracellular Vesicles | 2014 | 235 |