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Top Articles

#TitleJournalYearCitations
1Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelinesJournal of Extracellular Vesicles20187,596
2Biological properties of extracellular vesicles and their physiological functionsJournal of Extracellular Vesicles20154,243
3Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular VesiclesJournal of Extracellular Vesicles20142,206
4Routes and mechanisms of extracellular vesicle uptakeJournal of Extracellular Vesicles20141,993
5Standardization of sample collection, isolation and analysis methods in extracellular vesicle researchJournal of Extracellular Vesicles20131,916
6Optimized exosome isolation protocol for cell culture supernatant and human plasmaJournal of Extracellular Vesicles20151,271
7Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targetingJournal of Extracellular Vesicles20151,162
8Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paperJournal of Extracellular Vesicles20151,086
9Single‐step isolation of extracellular vesicles by size‐exclusion chromatographyJournal of Extracellular Vesicles2014869
10Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomesJournal of Extracellular Vesicles2013802
11Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide surveyJournal of Extracellular Vesicles2016766
12The impact of disparate isolation methods for extracellular vesicles on downstream RNA profilingJournal of Extracellular Vesicles2014751
13As we wait: coping with an imperfect nomenclature for extracellular vesiclesJournal of Extracellular Vesicles2013739
14Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell‐free bloodJournal of Extracellular Vesicles2014669
15Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paperJournal of Extracellular Vesicles2017589
16How pure are your vesicles?Journal of Extracellular Vesicles2013580
17High‐resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sourcesJournal of Extracellular Vesicles2016536
18Cellular stress conditions are reflected in the protein and RNA content of endothelial cell‐derived exosomesJournal of Extracellular Vesicles2012513
19Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugationJournal of Extracellular Vesicles2012482
20Extracellular vesicle sizing and enumeration by nanoparticle tracking analysisJournal of Extracellular Vesicles2013446
21Defining mesenchymal stromal cell (MSC)‐derived small extracellular vesicles for therapeutic applicationsJournal of Extracellular Vesicles2019440
22Macrophage‐dependent clearance of systemically administered B16BL6‐derived exosomes from the blood circulation in miceJournal of Extracellular Vesicles2015438
23EVpedia: an integrated database of high‐throughput data for systemic analyses of extracellular vesiclesJournal of Extracellular Vesicles2013422
24High‐speed centrifugation induces aggregation of extracellular vesiclesJournal of Extracellular Vesicles2015415
25Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclatureJournal of Extracellular Vesicles2019407
26Inhibiting extracellular vesicles formation and release: a review of EV inhibitorsJournal of Extracellular Vesicles2020407
27Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cellsJournal of Extracellular Vesicles2017404
28Quality and efficiency assessment of six extracellular vesicle isolation methods by nano‐flow cytometryJournal of Extracellular Vesicles2020390
29Importance of exosome depletion protocols to eliminate functional and RNA‐containing extracellular vesicles from fetal bovine serumJournal of Extracellular Vesicles2014367
30The influence of rotor type and centrifugation time on the yield and purity of extracellular vesiclesJournal of Extracellular Vesicles2014362
31Extracellular vesicle measurements with nanoparticle tracking analysis – An accuracy and repeatability comparison between NanoSight NS300 and ZetaViewJournal of Extracellular Vesicles2019357
32Comparative marker analysis of extracellular vesicles in different human cancer typesJournal of Extracellular Vesicles2013340
33ExoCarta as a resource for exosomal researchJournal of Extracellular Vesicles2012326
34A novel community driven software for functional enrichment analysis of extracellular vesicles dataJournal of Extracellular Vesicles2017325
35Exosomal miRNAs as cancer biomarkers and therapeutic targetsJournal of Extracellular Vesicles2016324
36Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approachesJournal of Extracellular Vesicles2024315
37Ginger‐derived nanoparticles protect against alcohol‐induced liver damageJournal of Extracellular Vesicles2015314
38Display of GPI‐anchored anti‐EGFR nanobodies on extracellular vesicles promotes tumour cell targetingJournal of Extracellular Vesicles2016307
39Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometerJournal of Extracellular Vesicles2015305
40Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasmaJournal of Extracellular Vesicles2018298
41Co‐isolation of extracellular vesicles and high‐density lipoproteins using density gradient ultracentrifugationJournal of Extracellular Vesicles2014284
42Comparative analysis of discrete exosome fractions obtained by differential centrifugationJournal of Extracellular Vesicles2014282
43MIFlowCyt‐EV: a framework for standardized reporting of extracellular vesicle flow cytometry experimentsJournal of Extracellular Vesicles2020282
44Comparison of small extracellular vesicles isolated from plasma by ultracentrifugation or size‐exclusion chromatography: yield, purity and functional potentialJournal of Extracellular Vesicles2019269
45Exosomal proteins as potential diagnostic markers in advanced non‐small cell lung carcinomaJournal of Extracellular Vesicles2015257
46Physical exercise induces rapid release of small extracellular vesicles into the circulationJournal of Extracellular Vesicles2015255
47Neutral sphingomyelinases control extracellular vesicles budding from the plasma membraneJournal of Extracellular Vesicles2017254
48Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane contentJournal of Extracellular Vesicles2015253
49Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancerJournal of Extracellular Vesicles2016251
50Isolation and characterization of platelet‐derived extracellular vesiclesJournal of Extracellular Vesicles2014250