| # | Title | Journal | Year | Citations |
|---|
| 1 | A new look at cerebrospinal fluid circulation | Fluids and Barriers of the CNS | 2014 | 596 |
| 2 | A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity | Fluids and Barriers of the CNS | 2020 | 575 |
| 3 | The hCMEC/D3 cell line as a model of the human blood brain barrier | Fluids and Barriers of the CNS | 2013 | 522 |
| 4 | Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence | Fluids and Barriers of the CNS | 2014 | 466 |
| 5 | Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation | Fluids and Barriers of the CNS | 2012 | 446 |
| 6 | The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility | Fluids and Barriers of the CNS | 2011 | 338 |
| 7 | Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences | Fluids and Barriers of the CNS | 2011 | 323 |
| 8 | Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood–brain barrier model for drug permeability studies | Fluids and Barriers of the CNS | 2013 | 311 |
| 9 | Claudin-5: gatekeeper of neurological function | Fluids and Barriers of the CNS | 2019 | 304 |
| 10 | Impedance-based cell monitoring: barrier properties and beyond | Fluids and Barriers of the CNS | 2013 | 291 |
| 11 | A perfused human blood–brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport | Fluids and Barriers of the CNS | 2018 | 235 |
| 12 | Drug transport in brain via the cerebrospinal fluid | Fluids and Barriers of the CNS | 2011 | 231 |
| 13 | Fluid and ion transfer across the blood–brain and blood–cerebrospinal fluid barriers; a comparative account of mechanisms and roles | Fluids and Barriers of the CNS | 2016 | 198 |
| 14 | Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle | Fluids and Barriers of the CNS | 2011 | 187 |
| 15 | A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood–brain barrier in ddY, FVB, and C57BL/6J mice | Fluids and Barriers of the CNS | 2013 | 185 |
| 16 | Vascular disruption and blood–brain barrier dysfunction in intracerebral hemorrhage | Fluids and Barriers of the CNS | 2014 | 174 |
| 17 | Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells | Fluids and Barriers of the CNS | 2013 | 170 |
| 18 | Influence of comorbidities in idiopathic normal pressure hydrocephalus — research and clinical care. A report of the ISHCSF task force on comorbidities in INPH | Fluids and Barriers of the CNS | 2013 | 167 |
| 19 | The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival | Fluids and Barriers of the CNS | 2011 | 162 |
| 20 | Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases | Fluids and Barriers of the CNS | 2019 | 156 |
| 21 | Pediatric hydrocephalus outcomes: a review | Fluids and Barriers of the CNS | 2012 | 149 |
| 22 | Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier | Fluids and Barriers of the CNS | 2018 | 142 |
| 23 | Influence of respiration on cerebrospinal fluid movement using magnetic resonance spin labeling | Fluids and Barriers of the CNS | 2013 | 141 |
| 24 | Choroid plexus and the blood–cerebrospinal fluid barrier in disease | Fluids and Barriers of the CNS | 2020 | 141 |
| 25 | Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells | Fluids and Barriers of the CNS | 2017 | 138 |
| 26 | Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs) | Fluids and Barriers of the CNS | 2017 | 120 |
| 27 | Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers | Fluids and Barriers of the CNS | 2018 | 119 |
| 28 | Adenosine receptor signaling: a key to opening the blood–brain door | Fluids and Barriers of the CNS | 2015 | 110 |
| 29 | The value of the cerebrospinal fluid tap test for predicting shunt effectiveness in idiopathic normal pressure hydrocephalus | Fluids and Barriers of the CNS | 2012 | 108 |
| 30 | Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells | Fluids and Barriers of the CNS | 2015 | 106 |
| 31 | Disruption of the hippocampal and hypothalamic blood–brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate | Fluids and Barriers of the CNS | 2019 | 106 |
| 32 | Modeling the blood–brain barrier using stem cell sources | Fluids and Barriers of the CNS | 2013 | 105 |
| 33 | Benchmarking in vitro tissue-engineered blood–brain barrier models | Fluids and Barriers of the CNS | 2018 | 105 |
| 34 | In vitro modeling of the neurovascular unit: advances in the field | Fluids and Barriers of the CNS | 2020 | 105 |
| 35 | Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent | Fluids and Barriers of the CNS | 2011 | 104 |
| 36 | Analysis of convective and diffusive transport in the brain interstitium | Fluids and Barriers of the CNS | 2019 | 102 |
| 37 | The mastermind approach to CNS drug therapy: translational prediction of human brain distribution, target site kinetics, and therapeutic effects | Fluids and Barriers of the CNS | 2013 | 98 |
| 38 | Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats | Fluids and Barriers of the CNS | 2014 | 97 |
| 39 | A new glaucoma hypothesis: a role of glymphatic system dysfunction | Fluids and Barriers of the CNS | 2015 | 93 |
| 40 | The glymphatic hypothesis: the theory and the evidence | Fluids and Barriers of the CNS | 2022 | 92 |
| 41 | Transcriptome signature of the adult mouse choroid plexus | Fluids and Barriers of the CNS | 2011 | 88 |
| 42 | Nonsurgical therapy for hydrocephalus: a comprehensive and critical review | Fluids and Barriers of the CNS | 2015 | 88 |
| 43 | Is bulk flow plausible in perivascular, paravascular and paravenous channels? | Fluids and Barriers of the CNS | 2018 | 86 |
| 44 | Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis | Fluids and Barriers of the CNS | 2018 | 86 |
| 45 | 1α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier | Fluids and Barriers of the CNS | 2011 | 85 |
| 46 | Clearance from the mouse brain by convection of interstitial fluid towards the ventricular system | Fluids and Barriers of the CNS | 2015 | 85 |
| 47 | Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation | Fluids and Barriers of the CNS | 2018 | 83 |
| 48 | Recent advances in human iPSC-derived models of the blood–brain barrier | Fluids and Barriers of the CNS | 2020 | 83 |
| 49 | Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D | Fluids and Barriers of the CNS | 2019 | 82 |
| 50 | Measuring intracranial pressure by invasive, less invasive or non-invasive means: limitations and avenues for improvement | Fluids and Barriers of the CNS | 2020 | 82 |
