4.2(top 10%)
impact factor
5.9K(top 5%)
papers
131.2K(top 5%)
citations
125(top 5%)
h-index
4.3(top 10%)
impact factor
8.0K
all documents
149.3K
doc citations
190(top 5%)
g-index

Top Articles

#TitleJournalYearCitations
1An epigenetic biomarker of aging for lifespan and healthspanAging20181,552
2DNA methylation GrimAge strongly predicts lifespan and healthspanAging20191,128
3Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesAging20161,014
4Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysisAging2020965
5DNA methylation-based measures of biological age: meta-analysis predicting time to deathAging2016786
6Why does COVID-19 disproportionately affect older people?Aging2020708
7Epigenetic clock analysis of diet, exercise, education, and lifestyle factorsAging2017521
8Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and agingAging2011520
9New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463Aging2017469
10Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophyAging2010462
11Role of Apoptosis in diseaseAging2012448
12Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscleAging2009428
13MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8Aging2009420
14Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studiesAging2018406
15Inflammaging: disturbed interplay between autophagy and inflammasomesAging2012379
16Polyamines in aging and diseaseAging2011376
17Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioningAging2015368
18Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patientsAging2015344
19ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in ItalyAging2020331
20Markers of cellular senescence. Telomere shortening as a marker of cellular senescenceAging2016312
21Mining TCGA database for genes of prognostic value in glioblastoma microenvironmentAging2018311
22Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990–2017: results from a global burden of disease study, 2017Aging2019310
23Fasting and cancer treatment in humans: A case series reportAging2009305
24Epidemiological, comorbidity factors with severity and prognosis of COVID-19: a systematic review and meta-analysisAging2020298
25The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathwayAging2010281
26Transposable elements become active and mobile in the genomes of aging mammalian somatic tissuesAging2013280
27Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspringAging2015276
28SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repairAging2009270
29The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men: a novel demonstrationAging2008270
30Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagyAging2009270
31Deep biomarkers of human aging: Application of deep neural networks to biomarker developmentAging2016266
32Functional metagenomic profiling of intestinal microbiome in extreme ageingAging2013263
33Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cellsAging2016261
34CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630Aging2017259
35Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissuesAging2012258
36Age-related changes in microRNA levels in serumAging2013257
37DNA methylation age of blood predicts future onset of lung cancer in the women's health initiativeAging2015254
38Epigenetic-aging-signature to determine age in different tissuesAging2011248
39Sarcopenia, obesity, and natural killer cell immune senescence in aging: Altered cytokine levels as a common mechanismAging2012247
40If started early in life, metformin treatment increases life span and postpones tumors in female SHR miceAging2011244
41p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuliAging2017244
42Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1Aging2020244
43A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addictionAging2010231
44IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine ‘Bystander senescence’Aging2012231
45Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven agingAging2012224
46miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissuesAging2010217
47Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skinAging2012215
48Complete cardiac regeneration in a mouse model of myocardial infarctionAging2012214
49NKG2D ligands mediate immunosurveillance of senescent cellsAging2016211
50The sirtuins, oxidative stress and aging: an emerging linkAging2013209