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Top Articles

#	Title	Journal	Year	Citations
1	4 Lactate Dehydrogenase	The Enzymes	1975	444
2	2 Evolutionary and Structural Relationships among Dehydrogenases	The Enzymes	1975	418
3	1 Steady State Kinetics	The Enzymes	1970	357
4	24 Bovine Pancreatic Ribonuclease	The Enzymes	1971	357
5	3 Alcohol Dehydrogenases	The Enzymes	1975	342
6	21 Vertebrate Lysozymes	The Enzymes	1972	315
7	The Many Roles of PCNA in Eukaryotic DNA Replication	The Enzymes	2016	216
8	7 Cytochromes c	The Enzymes	1975	200
9	9 Phospholipases	The Enzymes	1983	197
10	9 Nucleoside Diphosphokinases	The Enzymes	1973	196
11	1 Transient-State Kinetic Analysis of Enzyme Reaction Pathways	The Enzymes	1992	189
12	6 Molybdenum Iron-Sulfur Flauin Hydroxylases and Related Enzymes	The Enzymes	1975	167
13	7 Catalase	The Enzymes	1976	166
14	12 Pancreatic Ribonuclease	The Enzymes	1982	157
15	3 Flavin-Containing Dehydrogenases	The Enzymes	1976	154
16	21 Carbonic Anhydrase	The Enzymes	1971	152
17	8 Adenylate Kinase	The Enzymes	1973	151
18	18 Mammalian Alkaline Phosphatases	The Enzymes	1971	150
19	5 Glutamate Dehydrogenases	The Enzymes	1975	147
20	1 Glyceraldehyde-3-phosphate Dehydrogenase	The Enzymes	1976	145
21	11 Protein Proteinase Inhibitors—Molecular Aspects	The Enzymes	1971	139
22	2 Flavodoxins and Electron-Transferring Flavoproteins	The Enzymes	1975	131
23	5. Terminal Deoxynucleotidyl Transferase	The Enzymes	1974	129
24	24. The Glutamine Synthetase of Escherichia coli: Structure and Control	The Enzymes	1974	123
25	16 Subtilisins: Primary Structure, Chemical and Physical Properties	The Enzymes	1971	118
26	17 E. coli Alkaline Phosphatase	The Enzymes	1971	117
27	7 The Molecular Basis for Enzyme Regulation	The Enzymes	1970	116
28	6 Aldolases	The Enzymes	1972	116
29	4 Formation of Oxalacetate by CO2 Fixation on Phosphoenolpyruvate	The Enzymes	1972	116
30	3 Cyclic Nucleotide-Dependent Protein Kinases	The Enzymes	1986	115
31	12 Creatine Kinase (Adenosine 5′-Triphosphate-Creatine Phosphotransferase)	The Enzymes	1973	108
32	3 Carboxylic Ester Hydrolases	The Enzymes	1971	107
33	6 Plant and Animal Amylases	The Enzymes	1971	105
34	10 Amino Group Transfer	The Enzymes	1973	104
35	15 α-Glucan Phosphorylases–Chemical and Physical Basis of Catalysis and Regulation	The Enzymes	1972	101
36	20 Other Bacterial, Mold, and Yeast Proteases	The Enzymes	1971	99
37	23. Glutamine Synthetase of Mammals	The Enzymes	1974	94
38	15. Aminoacyl-tRNA Synthetases	The Enzymes	1974	93
39	2 Rapid Reactions and Transient States	The Enzymes	1970	90
40	14 Papain and Other Plant Sulfhydryl Proteolytic Enzymes	The Enzymes	1971	88
41	1 The Hexokinases	The Enzymes	1973	88
42	1 Tryptophan Synthetase	The Enzymes	1972	87
43	7 Flavoprotein Oxidases	The Enzymes	1975	87
44	The Importance of Being Modified	The Enzymes	2017	87
45	1 Carboxypeptidase A	The Enzymes	1971	85
46	20 β-Galactosidase	The Enzymes	1972	84
47	7 Amino Acid Decarboxylases	The Enzymes	1972	82
48	Saliva-Exosomics in Cancer: Molecular Characterization of Cancer-Derived Exosomes in Saliva	The Enzymes	2017	82
49	9 Enzymes as Control Elements in Metabolic Regulation	The Enzymes	1970	81
50	2 T4 RNA Ligase	The Enzymes	1982	81

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