| # | Title | Journal | Year | Citations |
|---|
| 1 | Analysis of drug combinations: current methodological landscape | Pharmacology Research and Perspectives | 2015 | 778 |
| 2 | Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases | Pharmacology Research and Perspectives | 2017 | 299 |
| 3 | Mechanisms of the gabapentinoids and α2δ‐1 calcium channel subunit in neuropathic pain | Pharmacology Research and Perspectives | 2016 | 186 |
| 4 | Role of endoplasmic reticulum stress in drug‐induced toxicity | Pharmacology Research and Perspectives | 2016 | 179 |
| 5 | The pharmacology and therapeutic applications of monoclonal antibodies | Pharmacology Research and Perspectives | 2019 | 154 |
| 6 | The nocebo effect of drugs | Pharmacology Research and Perspectives | 2016 | 129 |
| 7 | Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses | Pharmacology Research and Perspectives | 2015 | 127 |
| 8 | Diversity of molecular targets and signaling pathways for CBD | Pharmacology Research and Perspectives | 2020 | 126 |
| 9 | Mitochondrial fission – a drug target for cytoprotection or cytodestruction? | Pharmacology Research and Perspectives | 2016 | 109 |
| 10 | Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs | Pharmacology Research and Perspectives | 2018 | 109 |
| 11 | Preclinical animal anxiety research – flaws and prejudices | Pharmacology Research and Perspectives | 2016 | 94 |
| 12 | Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK1 inhibitor GSK2982772 in healthy volunteers | Pharmacology Research and Perspectives | 2017 | 94 |
| 13 | Effect of CYP3A perpetrators on ibrutinib exposure in healthy participants | Pharmacology Research and Perspectives | 2015 | 80 |
| 14 | Depressive disorders: Treatment failures and poor prognosis over the last 50 years | Pharmacology Research and Perspectives | 2019 | 76 |
| 15 | Molnupiravir: A new candidate for COVID‐19 treatment | Pharmacology Research and Perspectives | 2022 | 76 |
| 16 | Anti‐inflammatory, antiapoptotic, and antioxidant activity of fluoxetine | Pharmacology Research and Perspectives | 2016 | 75 |
| 17 | In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib | Pharmacology Research and Perspectives | 2015 | 73 |
| 18 | Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition | Pharmacology Research and Perspectives | 2019 | 73 |
| 19 | Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease | Pharmacology Research and Perspectives | 2019 | 71 |
| 20 | “LONG COVID”—A hypothesis for understanding the biological basis and pharmacological treatment strategy | Pharmacology Research and Perspectives | 2022 | 69 |
| 21 | Self‐medication misuse in the Middle East: a systematic literature review | Pharmacology Research and Perspectives | 2017 | 68 |
| 22 | Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose‐induced oxidative stress in type 1 diabetic mice | Pharmacology Research and Perspectives | 2016 | 67 |
| 23 | Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action | Pharmacology Research and Perspectives | 2015 | 66 |
| 24 | Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid‐lowering and insulin‐sensitizing effects in preclinical models | Pharmacology Research and Perspectives | 2015 | 65 |
| 25 | Pharmacology and physiology of gastrointestinal enteroendocrine cells | Pharmacology Research and Perspectives | 2015 | 64 |
| 26 | Dexmedetomidine preconditioning ameliorates kidney ischemia‐reperfusion injury | Pharmacology Research and Perspectives | 2014 | 61 |
| 27 | Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: A randomized, double‐blind, controlled trial | Pharmacology Research and Perspectives | 2021 | 60 |
| 28 | Evaluation of biomarkers for in vitro prediction of drug‐induced nephrotoxicity: comparison of HK‐2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells | Pharmacology Research and Perspectives | 2015 | 59 |
| 29 | p‐Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress | Pharmacology Research and Perspectives | 2015 | 59 |
| 30 | MicroRNAs in non‐small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential | Pharmacology Research and Perspectives | 2019 | 58 |
| 31 | Vancomycin therapeutic drug monitoring and population pharmacokinetic models in special patient subpopulations | Pharmacology Research and Perspectives | 2018 | 57 |
| 32 | Adverse drug reactions of montelukast in children and adults | Pharmacology Research and Perspectives | 2017 | 56 |
| 33 | Nucleotide analogues as inhibitors of SARS‐CoV Polymerase | Pharmacology Research and Perspectives | 2020 | 56 |
| 34 | Perivascular adipose tissue contains functional catecholamines | Pharmacology Research and Perspectives | 2014 | 55 |
| 35 | Effects of resveratrol on drug- and carcinogen-metabolizing enzymes, implications for cancer prevention | Pharmacology Research and Perspectives | 2017 | 54 |
| 36 | Ethics of animal research in human disease remediation, its institutional teaching; and alternatives to animal experimentation | Pharmacology Research and Perspectives | 2017 | 54 |
| 37 | Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist | Pharmacology Research and Perspectives | 2016 | 51 |
| 38 | Individualized medicine: Sex, hormones, genetics, and adverse drug reactions | Pharmacology Research and Perspectives | 2019 | 51 |
| 39 | Inhibition of Let‐7 microRNA attenuates myocardial remodeling and improves cardiac function postinfarction in mice | Pharmacology Research and Perspectives | 2014 | 49 |
| 40 | Effect of perampanel, a novel AMPA antagonist, on benzodiazepine‐resistant status epilepticus in a lithium‐pilocarpine rat model | Pharmacology Research and Perspectives | 2014 | 48 |
| 41 | Uricosuric targets of tranilast | Pharmacology Research and Perspectives | 2017 | 48 |
| 42 | Ajulemic acid: potential treatment for chronic inflammation | Pharmacology Research and Perspectives | 2018 | 48 |
| 43 | Drug discovery: Insights from the invertebrate Caenorhabditis elegans | Pharmacology Research and Perspectives | 2021 | 47 |
| 44 | An inhaled dose of budesonide induces genes involved in transcription and signaling in the human airways: enhancement of anti‐ and proinflammatory effector genes | Pharmacology Research and Perspectives | 2016 | 46 |
| 45 | Inhibition of adenosine deaminase (ADA)‐mediated metabolism of cordycepin by natural substances | Pharmacology Research and Perspectives | 2015 | 45 |
| 46 | From the dual function lead AP2238 to AP2469, a multi‐target‐directed ligand for the treatment of Alzheimer's disease | Pharmacology Research and Perspectives | 2014 | 44 |
| 47 | Revisiting the putative role of heme as a trigger of inflammation | Pharmacology Research and Perspectives | 2018 | 44 |
| 48 | MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo‐allergic and anaphylactoid reactions | Pharmacology Research and Perspectives | 2019 | 44 |
| 49 | Memantine protects thalamocortical hyper‐glutamatergic transmission induced by NMDA receptor antagonism via activation of system xc− | Pharmacology Research and Perspectives | 2019 | 44 |
| 50 | Antidepressant activity of fingolimod in mice | Pharmacology Research and Perspectives | 2015 | 42 |
