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Top Articles

#TitleJournalYearCitations
1The RIN: an RNA integrity number for assigning integrity values to RNA measurementsBMC Molecular Biology20062,136
2Selection of housekeeping genes for gene expression studies in human reticulocytes using real-time PCRBMC Molecular Biology20061,355
3MIQE précis: Practical implementation of minimum standard guidelines for fluorescence-based quantitative real-time PCR experimentsBMC Molecular Biology2010585
4Selection of reliable reference genes for gene expression studies in peach using real-time PCRBMC Molecular Biology2009580
5Identification and validation of reference genes for quantitative RT-PCR normalization in wheatBMC Molecular Biology2009575
6Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatmentBMC Molecular Biology2008527
7Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmonBMC Molecular Biology2005501
8Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCRBMC Molecular Biology2007460
9Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiaeBMC Molecular Biology2009419
10Validation of internal control for gene expression study in soybean by quantitative real-time PCRBMC Molecular Biology2008369
11Evaluation of putative reference genes for gene expression normalization in soybean by quantitative real-time RT-PCRBMC Molecular Biology2009369
12Lambda Red-mediated recombinogenic engineering of enterohemorrhagic and enteropathogenic E. coliBMC Molecular Biology2003335
13Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegansBMC Molecular Biology2008335
14Relative quantification of mRNA: comparison of methods currently used for real-time PCR data analysisBMC Molecular Biology2007329
15Members of miR-169 family are induced by high salinity and transiently inhibit the NF-YA transcription factorBMC Molecular Biology2009326
16Transcriptional oscillation of canonical clock genes in mouse peripheral tissuesBMC Molecular Biology2004266
17Identification of suitable internal control genes for expression studies in Coffea arabica under different experimental conditionsBMC Molecular Biology2009260
18Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancerBMC Molecular Biology2008231
19Novel reference genes for quantifying transcriptional responses of Escherichia coli to protein overexpression by quantitative PCRBMC Molecular Biology2011230
20HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTRBMC Molecular Biology2007224
21Identification and validation of housekeeping genes in brains of the desert locust Schistocerca gregaria under different developmental conditionsBMC Molecular Biology2009210
22Cruciform structures are a common DNA feature important for regulating biological processesBMC Molecular Biology2011209
23Selection of reference genes for gene expression studies in human neutrophils by real-time PCRBMC Molecular Biology2005200
24Selection of housekeeping genes for gene expression studies in larvae from flatfish using real-time PCRBMC Molecular Biology2008197
25Validation of reference genes for gene expression analysis in chicory (Cichorium intybus) using quantitative real-time PCRBMC Molecular Biology2010196
26Nucleophosmin: from structure and function to disease developmentBMC Molecular Biology2016194
27Evaluation of endogenous references for gene expression profiling in different tissues of the oriental fruit fly Bactrocera dorsalis (Diptera: Tephritidae)BMC Molecular Biology2010187
28Inactivation of nucleolin leads to nucleolar disruption, cell cycle arrest and defects in centrosome duplicationBMC Molecular Biology2007181
29Analysis of current and alternative phenol based RNA extraction methodologies for cyanobacteriaBMC Molecular Biology2009179
30Appropriate 'housekeeping' genes for use in expression profiling the effects of environmental estrogens in fishBMC Molecular Biology2007174
31The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammalsBMC Molecular Biology2008169
32Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cellsBMC Molecular Biology2009169
33Efficient four fragment cloning for the construction of vectors for targeted gene replacement in filamentous fungiBMC Molecular Biology2008156
34Selection of suitable housekeeping genes for expression analysis in glioblastoma using quantitative RT-PCRBMC Molecular Biology2009150
35Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibitionBMC Molecular Biology2007147
36In search of suitable reference genes for gene expression studies of human renal cell carcinoma by real-time PCRBMC Molecular Biology2007144
37Development and evaluation of different normalization strategies for gene expression studies in Candida albicans biofilms by real-time PCRBMC Molecular Biology2006143
38A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiationBMC Molecular Biology2008143
39DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progressionBMC Molecular Biology2010139
40Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependentBMC Molecular Biology2004135
41Validation of reference genes for quantitative RT-PCR studies of gene expression in perennial ryegrass (Lolium perenne L.)BMC Molecular Biology2010133
42Selection of reference genes for quantitative RT-PCR studies in Rhipicephalus (Boophilus) microplus and Rhipicephalus appendiculatus ticks and determination of the expression profile of Bm86BMC Molecular Biology2009132
43Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosaBMC Molecular Biology2008130
44Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest modelBMC Molecular Biology2008130
45Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposureBMC Molecular Biology2008130
46A direct repeat of E-box-like elements is required for cell-autonomous circadian rhythm of clock genesBMC Molecular Biology2008125
47Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectorsBMC Molecular Biology2004124
48Cloning and expression analysis of two distinct HIF-alpha isoforms--gcHIF-1alpha and gcHIF-4alpha--from the hypoxia-tolerant grass carp, Ctenopharyngodon idellusBMC Molecular Biology2006121
49The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific mannerBMC Molecular Biology2004120
50Small RNAs and the regulation of cis-natural antisense transcripts in ArabidopsisBMC Molecular Biology2008120