Antiviral Chemistry and Chemotherapy

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#	Title	Journal	Year	Citations
1	Cytokines and HIV-1: Interactions and Clinical Implications	Antiviral Chemistry and Chemotherapy	2001	280
2	Regiospecific Synthesis and Anti-Human Immunodeficiency Virus Activity of Novel 5-Substituted N-Alkylcarbamoyl and N,N-Dialkyl Carbamoyl 1,2,3-Triazole-TSAO Analogues	Antiviral Chemistry and Chemotherapy	1998	216
3	HPMPC (cidofovir), PMEA (adefovir) and Related Acyclic Nucleoside Phosphonate Analogues: A Review of their Pharmacology and Clinical Potential in the Treatment of Viral Infections	Antiviral Chemistry and Chemotherapy	1997	214
4	Evaluation of Immunomodulators, Interferons and Known in Vitro SARS-CoV Inhibitors for Inhibition of SARS-Cov Replication in BALB/c Mice	Antiviral Chemistry and Chemotherapy	2006	203
5	Amino Acid Ester Prodrugs of Acyclovir	Antiviral Chemistry and Chemotherapy	1992	194
6	Structural Features and Antiviral Activity of Sulphated Fucans from the Brown Seaweed Cystoseira Indica	Antiviral Chemistry and Chemotherapy	2007	164
7	Famciclovir and Penciclovir. The Mode of Action of Famciclovir Including Its Conversion to Penciclovir	Antiviral Chemistry and Chemotherapy	1993	156
8	Nanoparticulate Delivery Systems for Antiviral Drugs	Antiviral Chemistry and Chemotherapy	2010	154
9	Pharmacokinetics of Famciclovir in Man	Antiviral Chemistry and Chemotherapy	1993	136
10	Penciclovir: a review of its spectrum of activity, selectivity, and cross-resistance pattern	Antiviral Chemistry and Chemotherapy	1993	132
11	Inhibition of Severe Acute Respiratory Syndrome-Associated Coronavirus (SARSCoV) by Calpain Inhibitors and β-D-N⁴-Hydroxycytidine	Antiviral Chemistry and Chemotherapy	2004	127
12	Resistance of Hepatitis B Virus to Antiviral Drugs: Current Aspects and Directions for Future Investigation	Antiviral Chemistry and Chemotherapy	2001	124
13	Cidofovir, a New Agent with Potent Anti-Herpesvirus Activity	Antiviral Chemistry and Chemotherapy	1996	123
14	The Herpesvirus Proteases as Targets for Antiviral Chemotherapy	Antiviral Chemistry and Chemotherapy	2000	115
15	Polyanions — A Lost Chance in the Fight against HIV and other Virus Diseases?	Antiviral Chemistry and Chemotherapy	2000	114
16	Non-Nucleoside Reverse Transcriptase Inhibitors: The NNRTI Boom	Antiviral Chemistry and Chemotherapy	1999	113
17	Nucleosides for the treatment of respiratory RNA virus infections	Antiviral Chemistry and Chemotherapy	2018	113
18	Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses	Antiviral Chemistry and Chemotherapy	2018	113
19	Effect of Interferon-Alpha and Interferon-Inducers on West Nile Virus in Mouse and Hamster Animal Models	Antiviral Chemistry and Chemotherapy	2004	112
20	Synthesis, in Vitro Biological Evaluation and Oral Bioavailability of 9-[2-(Phosphonomethoxy)Propyl]Adenine (PMPA) Prodrugs	Antiviral Chemistry and Chemotherapy	1997	111
21	Anti-Human Immunodeficiency Virus Drug Combination Strategies	Antiviral Chemistry and Chemotherapy	1998	110
22	Inhibition of Hepatitis C Replicon RNA Synthesis by β-D-2′-deoxy-2′-fluoro-2′-C-Methylcytidine: A Specific Inhibitor of Hepatitis C Virus Replication	Antiviral Chemistry and Chemotherapy	2006	110
23	Mechanisms of Action of Ribavirin in Antiviral Therapies	Antiviral Chemistry and Chemotherapy	2001	109
24	The Application and Mechanism of Action of Ribavirin in Therapy of Hepatitis C	Antiviral Chemistry and Chemotherapy	2012	109
25	CCR5 Antagonists: Host-Targeted Antivirals for the Treatment of HIV Infection	Antiviral Chemistry and Chemotherapy	2005	106
26	Mozobil® (Plerixafor, AMD3100), 10 years after its approval by the US Food and Drug Administration	Antiviral Chemistry and Chemotherapy	2019	100
27	Inhibition of HIV Infection by Caffeoylquinic Acid Derivatives	Antiviral Chemistry and Chemotherapy	1993	97
28	The Mode of Action of Penciclovir	Antiviral Chemistry and Chemotherapy	1993	96
29	Activity of a Sulfated Polysaccharide Extracted from the Red Seaweed Aghardhiella Tenera against Human Immunodeficiency Virus and Other Enveloped Viruses	Antiviral Chemistry and Chemotherapy	1994	95
30	Carbohydrate-Binding Agents: A Potential Future Cornerstone for the Chemotherapy of Enveloped Viruses?	Antiviral Chemistry and Chemotherapy	2007	94
31	Anti-Influenza Virus Activity of Propolis in Vitro and its Efficacy against Influenza Infection in Mice	Antiviral Chemistry and Chemotherapy	2008	92
32	Isolation and Characterization of Novel Human Immunodeficiency Virus Integrase Inhibitors from Fungal Metabolites	Antiviral Chemistry and Chemotherapy	1999	91
33	Antiviral Portrait Series: 4. Polysuifates as Inhibitors of HIV and Other Enveloped Viruses	Antiviral Chemistry and Chemotherapy	1994	90
34	Medicinal Chemistry of Nucleoside Phosphonate Prodrugs for Antiviral Therapy	Antiviral Chemistry and Chemotherapy	2012	90
35	Antiviral Effect of Brassinosteroids against Herpes Virus and Arenaviruses	Antiviral Chemistry and Chemotherapy	2000	86
36	Antiretroviral Therapy in Macrophages: Implication for HIV Eradication	Antiviral Chemistry and Chemotherapy	2009	86
37	Elvitegravir: A New HIV Integrase Inhibitor	Antiviral Chemistry and Chemotherapy	2009	86
38	Laninamivir and its Prodrug, CS-8958: Long-Acting Neuraminidase Inhibitors for the Treatment of Influenza	Antiviral Chemistry and Chemotherapy	2010	86
39	Sulphated Polymers are Potent and Selective Inhibitors of Various Enveloped Viruses, Including Herpes Simplex Virus, Cytomegalovirus, Vesicular Stomatitis Virus, Respiratory Syncytial Virus, and Toga-, Arena- and Retroviruses	Antiviral Chemistry and Chemotherapy	1990	85
40	Epigallocatechin Gallate Inhibits the HIV Reverse Transcription Step	Antiviral Chemistry and Chemotherapy	2011	84
41	Phosphoramidates and phosphonamidates (ProTides) with antiviral activity	Antiviral Chemistry and Chemotherapy	2018	84
42	Synthesis and Antiviral Activities of 1,2,3-triazole Functionalized Thymidines: 1,3-dipolar Cycloaddition for Efficient Regioselective Diversity Generation	Antiviral Chemistry and Chemotherapy	2005	83
43	Treatment of Lethal Vaccinia Virus Respiratory Infections in Mice with Cidofovir	Antiviral Chemistry and Chemotherapy	2001	82
44	5′-Nor Carbocyclic 5′-Deoxy-5′-(Isobutylthio)Adenosine and a 2′,3′-Dideoxy-2′,3′-Didehydro Derivative	Antiviral Chemistry and Chemotherapy	2001	82
45	Action of Celgosivir (6 O-Butanoyl Castanospermine) against the Pestivirus BVDV: Implications for the Treatment of Hepatitis C	Antiviral Chemistry and Chemotherapy	2004	80
46	Antiviral Activity and Mode of Action Studies of Ribavirin and Mycophenolic Acid against Orthopoxviruses in Vitro	Antiviral Chemistry and Chemotherapy	2001	78
47	In Vitro and in Vivo Activities of T-705 and Oseltamivir against Influenza Virus	Antiviral Chemistry and Chemotherapy	2003	78
48	Bevirimat: A Novel Maturation Inhibitor for the Treatment of HIV-1 Infection	Antiviral Chemistry and Chemotherapy	2008	78
49	Novel DL-Galactan Hybrids from the Red Seaweed Gymnogongrus Torulosus are Potent Inhibitors of Herpes Simplex Virus and Dengue Virus	Antiviral Chemistry and Chemotherapy	2002	76
50	Thiopurine Analogue Inhibitors of Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease, a Deubiquitinating and deISGylating Enzyme	Antiviral Chemistry and Chemotherapy	2009	74

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