# | Title | Journal | Year | Citations |
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1 | Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors | Assay and Drug Development Technologies | 2014 | 1,793 |
2 | Molecular Interaction Studies Using Microscale Thermophoresis | Assay and Drug Development Technologies | 2011 | 655 |
3 | Bioluminescent Assays for High-Throughput Screening | Assay and Drug Development Technologies | 2007 | 369 |
4 | Zebrafish: A Preclinical Model for Drug Screening | Assay and Drug Development Technologies | 2002 | 351 |
5 | Application of Real-Time Cell Electronic Sensing (RT-CES) Technology to Cell-Based Assays | Assay and Drug Development Technologies | 2004 | 343 |
6 | Improving the Solubility and Pharmacological Efficacy of Curcumin by Heat Treatment | Assay and Drug Development Technologies | 2007 | 266 |
7 | Use of Multiple Assay Endpoints to Investigate the Effects of Incubation Time, Dose of Toxin, and Plating Density in Cell-Based Cytotoxicity Assays | Assay and Drug Development Technologies | 2004 | 260 |
8 | Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue DiseasesPossibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure | Assay and Drug Development Technologies | 2013 | 226 |
9 | ADP-Glo: A Bioluminescent and Homogeneous ADP Monitoring Assay for Kinases | Assay and Drug Development Technologies | 2009 | 198 |
10 | Label-Free Cell-Based Assays with Optical Biosensors in Drug Discovery | Assay and Drug Development Technologies | 2006 | 189 |
11 | Advances in High Content Screening for Drug Discovery | Assay and Drug Development Technologies | 2003 | 182 |
12 | Dynamic and Label-Free Cell-Based Assays Using the Real-Time Cell Electronic Sensing System | Assay and Drug Development Technologies | 2006 | 163 |
13 | A FRET-Based Assay Platform for Ultra-High Density Drug Screening of Protein Kinases and Phosphatases | Assay and Drug Development Technologies | 2002 | 147 |
14 | High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures | Assay and Drug Development Technologies | 2015 | 135 |
15 | High Throughput Screening Technologies for Direct Cyclic AMP Measurement | Assay and Drug Development Technologies | 2003 | 133 |
16 | Identification and Characterization of Pharmacological Chaperones to Correct Enzyme Deficiencies in Lysosomal Storage Disorders | Assay and Drug Development Technologies | 2011 | 130 |
17 | A Robotic Platform for Quantitative High-Throughput Screening | Assay and Drug Development Technologies | 2008 | 126 |
18 | High Throughput Assay Technologies for Ion Channel Drug Discovery | Assay and Drug Development Technologies | 2004 | 120 |
19 | High-Throughput Screening with Quantitation of ATP Consumption: A Universal Non-Radioisotope, Homogeneous Assay for Protein Kinase | Assay and Drug Development Technologies | 2004 | 118 |
20 | Thermal Denaturation Assays in Chemical Biology | Assay and Drug Development Technologies | 2012 | 118 |
21 | AlphaLISA Immunoassay Platform— The “No-Wash” High-Throughput Alternative to ELISA | Assay and Drug Development Technologies | 2009 | 114 |
22 | The Cellular Distribution of Fluorescently Labeled Arrestins Provides a Robust, Sensitive, and Universal Assay for Screening G Protein-Coupled Receptors | Assay and Drug Development Technologies | 2002 | 112 |
23 | High Throughput Ion-Channel Pharmacology: Planar-Array-Based Voltage Clamp | Assay and Drug Development Technologies | 2003 | 111 |
24 | High-Content Assays for Hepatotoxicity Using Induced Pluripotent Stem Cell–Derived Cells | Assay and Drug Development Technologies | 2014 | 111 |
25 | In Vitro, Ex Vivo, andIn VivoMethodological Approaches for Studying Therapeutic Targets of Osteoporosis and Degenerative Joint Diseases: How Biomarkers Can Assist? | Assay and Drug Development Technologies | 2005 | 107 |
26 | A High Throughput Luminescent Assay for Glycogen Synthase Kinase-3β Inhibitors | Assay and Drug Development Technologies | 2007 | 107 |
27 | High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes | Assay and Drug Development Technologies | 2015 | 107 |
28 | Development of a 384-Well Colorimetric Assay to Quantify Hydrogen Peroxide Generated by the Redox Cycling of Compounds in the Presence of Reducing Agents | Assay and Drug Development Technologies | 2008 | 106 |
29 | Scintillation Proximity Assays in High-Throughput Screening | Assay and Drug Development Technologies | 2008 | 105 |
30 | Label-Free Cytotoxicity Screening Assay by Digital Holographic Microscopy | Assay and Drug Development Technologies | 2013 | 105 |
31 | HTS Identifies Novel and Specific Uncompetitive Inhibitors of the Two-Component NS2B-NS3 Proteinase of West Nile Virus | Assay and Drug Development Technologies | 2007 | 95 |
32 | Primary Cells and Stem Cells in Drug Discovery: Emerging Tools for High-Throughput Screening | Assay and Drug Development Technologies | 2011 | 94 |
33 | Profiling the NIH Small Molecule Repository for Compounds That Generate H2O2by Redox Cycling in Reducing Environments | Assay and Drug Development Technologies | 2010 | 93 |
34 | The Zebrafish: A Powerful Platform forIn Vivo, HTS Drug Discovery | Assay and Drug Development Technologies | 2011 | 91 |
35 | Enzyme Fragment Complementation: A Flexible High Throughput Screening Assay Technology | Assay and Drug Development Technologies | 2002 | 90 |
36 | Biophysical Methods for Monitoring Cell-Substrate Interactions in Drug Discovery | Assay and Drug Development Technologies | 2003 | 90 |
37 | Characterization of Potassium Channel Modulators with QPatch™ Automated Patch-Clamp Technology: System Characteristics and Performance | Assay and Drug Development Technologies | 2003 | 89 |
38 | Emerging Concepts of Guanine Nucleotide-Binding Protein-Coupled Receptor (GPCR) Function and Implications for High Throughput Screening | Assay and Drug Development Technologies | 2007 | 89 |
39 | Impedance-Based Detection of Beating Rhythm and Proarrhythmic Effects of Compounds on Stem Cell-Derived Cardiomyocytes | Assay and Drug Development Technologies | 2011 | 89 |
40 | Computational and Practical Aspects of Drug Repositioning | Assay and Drug Development Technologies | 2015 | 89 |
41 | Automated Tight Seal Electrophysiology for Assessing the Potential hERG Liability of Pharmaceutical Compounds | Assay and Drug Development Technologies | 2004 | 86 |
42 | Drug Discovery Approaches Utilizing Three-Dimensional Cell Culture | Assay and Drug Development Technologies | 2016 | 85 |
43 | An Automated Liquid Chromatography-Mass Spectrometry Process to Determine Metabolic Stability Half-Life and Intrinsic Clearance of Drug Candidates by Substrate Depletion | Assay and Drug Development Technologies | 2008 | 83 |
44 | Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis | Assay and Drug Development Technologies | 2016 | 83 |
45 | Functional Assay of Voltage-Gated Sodium Channels Using Membrane Potential-Sensitive Dyes | Assay and Drug Development Technologies | 2004 | 81 |
46 | Kinetic Exclusion Assay Technology: Characterization of Molecular Interactions | Assay and Drug Development Technologies | 2004 | 79 |
47 | Cellular Dielectric Spectroscopy: A Label-Free Comprehensive Platform for Functional Evaluation of Endogenous Receptors | Assay and Drug Development Technologies | 2006 | 79 |
48 | High-Content Assay to Identify Inhibitors of Dengue Virus Infection | Assay and Drug Development Technologies | 2010 | 78 |
49 | Characterization of a hERG Screen Using the IonWorks HT: Comparison to a hERG Rubidium Efflux Screen | Assay and Drug Development Technologies | 2005 | 77 |
50 | βGalactosidase Complementation: A Cell-Based Luminescent Assay Platform for Drug Discovery | Assay and Drug Development Technologies | 2007 | 77 |