| 1 | Myeloid-Derived Suppressor Cells | Cancer Immunology Research | 2017 | 1,393 |
| 2 | PD-L1 Expression in Triple-Negative Breast Cancer | Cancer Immunology Research | 2014 | 1,031 |
| 3 | NF-κB, an Active Player in Human Cancers | Cancer Immunology Research | 2014 | 933 |
| 4 | Tumor Microenvironment Characterization in Gastric Cancer Identifies Prognostic and Immunotherapeutically Relevant Gene Signatures | Cancer Immunology Research | 2019 | 665 |
| 5 | Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies | Cancer Immunology Research | 2014 | 656 |
| 6 | Anti-CTLA-4 Antibodies of IgG2a Isotype Enhance Antitumor Activity through Reduction of Intratumoral Regulatory T Cells | Cancer Immunology Research | 2013 | 644 |
| 7 | The Interplay of Immunotherapy and Chemotherapy: Harnessing Potential Synergies | Cancer Immunology Research | 2015 | 626 |
| 8 | Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity | Cancer Immunology Research | 2014 | 516 |
| 9 | Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen | Cancer Immunology Research | 2015 | 514 |
| 10 | An Abscopal Response to Radiation and Ipilimumab in a Patient with Metastatic Non–Small Cell Lung Cancer | Cancer Immunology Research | 2013 | 497 |
| 11 | In Vitro
Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and
In Vivo
Toxicology in Non-Human Primates | Cancer Immunology Research | 2014 | 461 |
| 12 | T Cells Expressing Chimeric Antigen Receptors Can Cause Anaphylaxis in Humans | Cancer Immunology Research | 2013 | 459 |
| 13 | NKG2D Receptor and Its Ligands in Host Defense | Cancer Immunology Research | 2015 | 457 |
| 14 | Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies | Cancer Immunology Research | 2015 | 456 |
| 15 | Bevacizumab plus Ipilimumab in Patients with Metastatic Melanoma | Cancer Immunology Research | 2014 | 444 |
| 16 | T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells | Cancer Immunology Research | 2016 | 442 |
| 17 | Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC | Cancer Immunology Research | 2017 | 442 |
| 18 | Tumors: Wounds That Do Not Heal—Redux | Cancer Immunology Research | 2015 | 431 |
| 19 | Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells | Cancer Immunology Research | 2015 | 413 |
| 20 | The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for
In Vivo
Antitumor Activity | Cancer Immunology Research | 2015 | 410 |
| 21 | Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation | Cancer Immunology Research | 2014 | 390 |
| 22 | Chemokines in Cancer | Cancer Immunology Research | 2014 | 366 |
| 23 | Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade | Cancer Immunology Research | 2016 | 364 |
| 24 | Antibody-Dependent Cellular Cytotoxicity Activity of a Novel Anti–PD-L1 Antibody Avelumab (MSB0010718C) on Human Tumor Cells | Cancer Immunology Research | 2015 | 359 |
| 25 | Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer | Cancer Immunology Research | 2017 | 355 |
| 26 | Comprehensive Meta-analysis of Key Immune-Related Adverse Events from CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients | Cancer Immunology Research | 2017 | 352 |
| 27 | IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype | Cancer Immunology Research | 2019 | 345 |
| 28 | HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade | Cancer Immunology Research | 2015 | 341 |
| 29 | Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma | Cancer Immunology Research | 2015 | 339 |
| 30 | The Immunological Synapse | Cancer Immunology Research | 2014 | 335 |
| 31 | Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery | Cancer Immunology Research | 2017 | 315 |
| 32 | Reversal of NK-Cell Exhaustion in Advanced Melanoma by Tim-3 Blockade | Cancer Immunology Research | 2014 | 314 |
| 33 | Identification and Characterization of MEDI4736, an Antagonistic Anti–PD-L1 Monoclonal Antibody | Cancer Immunology Research | 2015 | 314 |
| 34 | Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors | Cancer Immunology Research | 2015 | 314 |
| 35 | Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer | Cancer Immunology Research | 2018 | 309 |
| 36 | PD-1 Blockade Expands Intratumoral Memory T Cells | Cancer Immunology Research | 2016 | 304 |
| 37 | Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model | Cancer Immunology Research | 2016 | 304 |
| 38 | PD-1 Restrains Radiotherapy-Induced Abscopal Effect | Cancer Immunology Research | 2015 | 303 |
| 39 | T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection | Cancer Immunology Research | 2018 | 297 |
| 40 | PD-L1 Expression Correlates with Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer | Cancer Immunology Research | 2015 | 295 |
| 41 | Soluble PD-L1 as a Biomarker in Malignant Melanoma Treated with Checkpoint Blockade | Cancer Immunology Research | 2017 | 292 |
| 42 | Oncolytic Viruses and Their Application to Cancer Immunotherapy | Cancer Immunology Research | 2014 | 279 |
| 43 | Inflammasomes and Cancer | Cancer Immunology Research | 2017 | 278 |
| 44 | PD-L1 Expression in the Merkel Cell Carcinoma Microenvironment: Association with Inflammation, Merkel Cell Polyomavirus, and Overall Survival | Cancer Immunology Research | 2013 | 276 |
| 45 | Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues | Cancer Immunology Research | 2015 | 275 |
| 46 | Phase I Trial of Autologous CAR T Cells Targeting NKG2D Ligands in Patients with AML/MDS and Multiple Myeloma | Cancer Immunology Research | 2019 | 275 |
| 47 | Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs | Cancer Immunology Research | 2018 | 274 |
| 48 | PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti–PD-1 Therapy | Cancer Immunology Research | 2018 | 273 |
| 49 | Programmed Cell Death Ligand 1 (PD-L1) Signaling Regulates Macrophage Proliferation and Activation | Cancer Immunology Research | 2018 | 269 |
| 50 | Chimeric Antigen Receptor T Cells with Dissociated Signaling Domains Exhibit Focused Antitumor Activity with Reduced Potential for Toxicity
In Vivo | Cancer Immunology Research | 2013 | 268 |