| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic Epidemiology of COPD (COPDGene) Study Design | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2011 | 1,007 |
| 2 | St. George's Respiratory Questionnaire: MCID | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 713 |
| 3 | Identifying Individuals with Physcian Diagnosed COPD in Health Administrative Databases | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2009 | 505 |
| 4 | Minimal Clinically Important Differences in COPD Lung Function | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 398 |
| 5 | Minimally Clinically Important Difference for the UCSD Shortness of Breath Questionnaire, Borg Scale, and Visual Analog Scale | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 309 |
| 6 | Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease: GOLD Executive Summary Updated 2003 | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2004 | 291 |
| 7 | Alveolar Macrophages as Orchestrators of COPD | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2004 | 273 |
| 8 | The Burden of Obstructive Lung Disease Initiative (BOLD): Rationale and Design | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 256 |
| 9 | Minimal Clinically Important Differences in the Six-Minute Walk Test and the Incremental Shuttle Walking Test | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 249 |
| 10 | COPD as a Lung Disease with Systemic Consequences – Clinical Impact, Mechanisms, and Potential for Early Intervention | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2008 | 240 |
| 11 | Measurement Properties and Interpretability of the Chronic Respiratory Disease Questionnaire (CRQ) | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 237 |
| 12 | COPD as a Systemic Disease | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2008 | 204 |
| 13 | The Economic Impact of Exacerbations of Chronic Obstructive Pulmonary Disease and Exacerbation Definition: A Review | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2010 | 203 |
| 14 | The Electrophoretic α1-Globulin Pattern of Serum in α1-Antitrypsin Deficiency | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2013 | 201 |
| 15 | Development and Initial Validation of a Self-Scored COPD Population Screener Questionnaire (COPD-PS) | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2008 | 200 |
| 16 | Approaches and Recommendations for Estimating Minimally Important Differences for Health-Related Quality of Life Measures | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 194 |
| 17 | Acute Exacerbations of COPD in the United States: Inpatient Burden and Predictors of Costs and Mortality | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2012 | 171 |
| 18 | The Effects of Air Pollution and Temperature on COPD | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2016 | 163 |
| 19 | Dyspnea and Activity Limitation in COPD: Mechanical Factors | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2007 | 160 |
| 20 | Augmentation Therapy for α1Antitrypsin Deficiency: A Meta-Analysis | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2009 | 160 |
| 21 | The Clinical Importance of Dynamic Lung Hyperinflation in COPD | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2006 | 158 |
| 22 | Mortality in COPD: Causes, Risk Factors, and Prevention | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2010 | 158 |
| 23 | The MCID of the Transition Dyspnea Index is a Total Score of One Unit | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 157 |
| 24 | Chronic Obstructive Pulmonary Disease and SocioEconomic Status: a Systematic Review | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2012 | 156 |
| 25 | Effect of Fluticasone Propionate/Salmeterol (250/50) on COPD Exacerbations and Impact on Patient Outcomes | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2009 | 154 |
| 26 | Clinical Trial Design Considerations in Assessing Long‐Term Functional Impacts of Tiotropium in COPD: The Uplift Trial | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2004 | 152 |
| 27 | Assessment of the Economic Burden of COPD in the U.S.: A Review and Synthesis of the Literature | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2006 | 150 |
| 28 | Outdoor Air Pollution and COPD-Related Emergency Department Visits, Hospital Admissions, and Mortality: A Meta-Analysis | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2017 | 145 |
| 29 | A Combined Pulmonary-Radiology Workshop for Visual Evaluation of COPD: Study Design, Chest CT Findings and Concordance with Quantitative Evaluation | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2012 | 143 |
| 30 | Assessing the Minimally Clinically Significant Difference: Scientific Considerations, Challenges and Solutions | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 141 |
| 31 | Formoterol and Tiotropium Compared With Tiotropium Alone for Treatment of COPD | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2009 | 130 |
| 32 | Medical Utilization and Cost in Patients with Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Asthma | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2014 | 126 |
| 33 | Efficacy and Safety of a 12-week Treatment with Twice-daily Aclidinium Bromide in COPD Patients (ACCORD COPD I) | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2012 | 125 |
| 34 | The Prevalence of Metabolic Syndrome In Chronic Obstructive Pulmonary Disease: A Systematic Review | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2016 | 125 |
| 35 | The Role of Oxidative Stress in Chronic Obstructive Pulmonary Disease | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2004 | 122 |
| 36 | Activity Monitoring and Energy Expenditure in COPD Patients: A Validation Study | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2007 | 122 |
| 37 | Canadian Cohort Obstructive Lung Disease (CanCOLD): Fulfilling the Need for Longitudinal Observational Studies in COPD | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2014 | 122 |
| 38 | A Comparison of the Assessment of Quality of Life with CAT, CCQ, and SGRQ in COPD Patients Participating in Pulmonary Rehabilitation | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2012 | 120 |
| 39 | Histone Deacetylation: An Important Mechanism in Inflammatory Lung Diseases | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 119 |
| 40 | Phenotypes of Chronic Obstructive Pulmonary Disease | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2007 | 116 |
| 41 | The Multiple Facets of Cigarette Addiction and What They Mean for Encouraging and Helping Smokers to Stop | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2009 | 116 |
| 42 | The Burden of Obstructive Lung Disease Initiative (BOLD): rationale and design | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 116 |
| 43 | Health Status and the Spiral of Decline | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2009 | 115 |
| 44 | Respiratory and Limb Muscle Dysfunction in COPD | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2015 | 113 |
| 45 | Red Blood Cell Distribution and Survival in Patients with Chronic Obstructive Pulmonary Disease | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2013 | 112 |
| 46 | Oxidative Stress and Respiratory System: Pharmacological and Clinical Reappraisal of N-Acetylcysteine | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2014 | 111 |
| 47 | COPD: A Pediatric Disease | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2008 | 110 |
| 48 | Outcome in Adult Bronchiectasis | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 106 |
| 49 | Trends and Cardiovascular Co-morbidities of COPD Patients in the Veterans Administration Medical System, 1991–1999 | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2005 | 103 |
| 50 | Asthma, Chronic Obstructive Pulmonary Disease, and Mortality in the U.S. Population | COPD: Journal of Chronic Obstructive Pulmonary Disease | 2011 | 103 |
