| # | Title | Journal | Year | Citations |
|---|
| 1 | Breeding of a Non-Obese, Diabetic Strain of Mice | Experimental Animals | 1980 | 933 |
| 2 | Effect of Three Types of Mixed Anesthetic Agents Alternate to Ketamine in Mice | Experimental Animals | 2011 | 419 |
| 3 | Genetic Differences among C57BL/6 Substrains | Experimental Animals | 2009 | 296 |
| 4 | Changes in Colonic Mucosal Permeability in Mouse Colitis Induced with Dextran Sulfate Sodium. | Experimental Animals | 1999 | 243 |
| 5 | Involvement of Sex, Strain and Age Factors in High Fat Diet-Induced Obesity in C57BL/6J and BALB/cA Mice | Experimental Animals | 2007 | 159 |
| 6 | Strain and Sex Differences in Anxiety-Like and Social Behaviors in C57BL/6J and BALB/cJ Mice | Experimental Animals | 2011 | 159 |
| 7 | Dextran Sodium Sulfate-Induced Colitis in Germ-Free IQI/Jic Mice. | Experimental Animals | 2001 | 146 |
| 8 | Histological Analysis of Murine Colitis Induced by Dextran Sulfate Sodium of Different Molecular Weights. | Experimental Animals | 2000 | 144 |
| 9 | High-efficiency CAG-FLPe Deleter Mice in C57BL/6J Background | Experimental Animals | 2006 | 139 |
| 10 | High fat diet induced obesity model using four strains of mice: Kunming, C57BL/6, BALB/c and ICR | Experimental Animals | 2020 | 127 |
| 11 | The Rat Model of Type 2 Diabetic Mellitus and Its Glycometabolism Characters | Experimental Animals | 2003 | 125 |
| 12 | Dopamine Dynamics and Signaling in <i>Drosophila</i>: An Overview of Genes, Drugs and Behavioral Paradigms | Experimental Animals | 2014 | 124 |
| 13 | A New Mouse Model of Spontaneous Diabetes Derived from ddY Strain. | Experimental Animals | 1999 | 120 |
| 14 | Chick embryo chorioallantoic membrane (CAM): an alternative predictive model in acute toxicological studies for anti-cancer drugs | Experimental Animals | 2015 | 117 |
| 15 | Transgenic Mouse Sperm that Have Green Acrosome and Red Mitochondria Allow Visualization of Sperm and Their Acrosome Reaction in Vivo | Experimental Animals | 2010 | 116 |
| 16 | Breeding of Mice Strains for Diabetes Mellitus | Experimental Animals | 1969 | 114 |
| 17 | Lipid Mediators in Life Science | Experimental Animals | 2011 | 113 |
| 18 | Histochemical, Lectin-Histochemical and Morphometrical Characteristics of Intestinal Goblet Cells of Germfree and Conventional Mice. | Experimental Animals | 1996 | 110 |
| 19 | Simple and Efficient Vitrification Procedure for Cryopreservation of Mouse Embryos. | Experimental Animals | 1997 | 106 |
| 20 | Type 2 Diabetes Mellitus in Obese Mouse Model Induced by Monosodium Glutamate | Experimental Animals | 2006 | 106 |
| 21 | The aryl hydrocarbon receptor: a multifunctional chemical sensor for host defense and homeostatic maintenance | Experimental Animals | 2017 | 105 |
| 22 | Virucidal Efficacy of Physico-chemical Treatments Against Coronaviruses and Parvoviruses of Laboratory Animals | Experimental Animals | 1988 | 100 |
| 23 | Canine X-Linked Muscular Dystrophy in Japan (CXMDJ). | Experimental Animals | 2003 | 100 |
| 24 | Comparative analysis of the intestinal flora in type 2 diabetes and nondiabetic mice | Experimental Animals | 2017 | 94 |
| 25 | Effect of Castration on the Appearance of Diabetes in NOD Mouse | Experimental Animals | 1981 | 90 |
| 26 | Vital signs monitoring during injectable and inhalant anesthesia in mice | Experimental Animals | 2015 | 88 |
| 27 | Angptl3-null Mice Show Low Plasma Lipid Concentrations by Enhanced Lipoprotein Lipase Activity | Experimental Animals | 2006 | 86 |
| 28 | Usefulness of Rat Skin as a Substitute for Human Skin in the in Vitro Skin Permeation Study | Experimental Animals | 2011 | 82 |
| 29 | Protective effects of sulforaphane on diabetic retinopathy: activation of the Nrf2 pathway and inhibition of NLRP3 inflammasome formation | Experimental Animals | 2019 | 81 |
| 30 | Cryopreservation of Mouse Spermatozoa from Inbred and F<SUB>1</SUB> Hybrid Strains | Experimental Animals | 1993 | 78 |
| 31 | Ginsenoside Rb1 improves cardiac function and remodeling in heart failure | Experimental Animals | 2017 | 77 |
| 32 | Effect of Treadmill Exercise on Bone Mass in Female Rats | Experimental Animals | 2005 | 75 |
| 33 | Diabetic Complications in Obese Type 2 Diabetic Rat Models | Experimental Animals | 2014 | 75 |
| 34 | Epilepsy Like Anomaly of Mice | Experimental Animals | 1959 | 74 |
| 35 | 日本在来マウスから育成した系統 | Experimental Animals | 1957 | 72 |
| 36 | A Novel Model of Obesity-Related Diabetes: Introgression of the Leprfa Allele of the Zucker Fatty Rat into Nonobese Spontaneously Diabetic Torii (SDT) Rats | Experimental Animals | 2005 | 71 |
| 37 | A Comparative Genetic Map of Rat, Mouse and Human Genomes. | Experimental Animals | 1998 | 69 |
| 38 | Anesthetic Effects of a Mixture of Medetomidine, Midazolam and Butorphanol in Two Strains of Mice | Experimental Animals | 2013 | 69 |
| 39 | Animal Models for Human Polycystic Kidney Disease | Experimental Animals | 2012 | 67 |
| 40 | Morris water maze: a versatile and pertinent tool for assessing spatial learning and memory | Experimental Animals | 2022 | 67 |
| 41 | Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9 | Experimental Animals | 2015 | 66 |
| 42 | Diabetic Complications in a New Animal Model (TSOD mouse) of Spontaneous NIDDM with Obesity | Experimental Animals | 2005 | 64 |
| 43 | Diabetes-Associated Complications in Spontaneously Diabetic Torii Fatty Rats | Experimental Animals | 2008 | 64 |
| 44 | Expanding Members and Roles of the Calpain Superfamily and Their Genetically Modified Animals | Experimental Animals | 2010 | 64 |
| 45 | National BioResource Project-Rat and Related Activities | Experimental Animals | 2009 | 63 |
| 46 | Effects of Room Temperature on Reproduction, Body and Organ Weights, Food and Water Intakes, and Hematology in Mice | Experimental Animals | 1983 | 62 |
| 47 | Determination of Serum C-Reactive Protein (CRP) in Healthy Beagle Dogs of Various Ages and Pregnant Beagle Dogs | Experimental Animals | 2003 | 61 |
| 48 | Age-Related Changes in Blood Pressure, Hematological Values, Concentrations of Serum Biochemical Constituents and Weights of Organs in the SHR/Izm, SHRSP/Izm and WKY/Izm | Experimental Animals | 2004 | 61 |
| 49 | Characterization of a Novel Polycystic Kidney Rat Model with Accompanying Polycystic Liver. | Experimental Animals | 2000 | 60 |
| 50 | Comparative study of behavioural tests in the SOD1G93A mouse model of amyotrophic lateral sclerosis | Experimental Animals | 2015 | 60 |
