Annual Reports in Medicinal Chemistry

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1.8K(top 10%)

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11.6K(top 20%)

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36(top 20%)

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1.3(top 50%)

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2.2K

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Top Articles

#	Title	Journal	Year	Citations
1	Chapter 26. Privileged structures — An update	Annual Reports in Medicinal Chemistry	2000	245
2	Chapter 33. Plasma Protein Binding of Drugs	Annual Reports in Medicinal Chemistry	1996	228
3	Chemoinformatics: What is it and How does it Impact Drug Discovery.	Annual Reports in Medicinal Chemistry	1998	131
4	Deuterium in Drug Discovery and Development	Annual Reports in Medicinal Chemistry	2011	94
5	Chapter 27. Bioisosterism in Drug Design	Annual Reports in Medicinal Chemistry	1986	86
6	Chapter 32. Taxol: From Discovery to Therapeutic Use	Annual Reports in Medicinal Chemistry	1993	78
7	Chapter 33. Recent Advances in the Generation of Molecular Diversity	Annual Reports in Medicinal Chemistry	1993	76
8	Role of Physicochemical Properties and Ligand Lipophilicity Efficiency in Addressing Drug Safety Risks	Annual Reports in Medicinal Chemistry	2010	71
9	Chapter 15. HIV Protease Inhibitors	Annual Reports in Medicinal Chemistry	1991	68
10	Comparative Protein Structure Modeling and its Applications to Drug Discovery	Annual Reports in Medicinal Chemistry	2004	68
11	Chapter 21. Selective Cyclooxygenase-2 Inhibitors	Annual Reports in Medicinal Chemistry	1997	67
12	Glossary of Terms Used in Computational Drug Design (IUPAC Recommendations 1997)	Annual Reports in Medicinal Chemistry	1998	67
13	Chapter 29. Principles for multivalent ligand design	Annual Reports in Medicinal Chemistry	2000	64
14	Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy	Annual Reports in Medicinal Chemistry	2020	63
15	Glossary of Terms Used in Medicinal Chemistry (IUPAC Recommendations 1997)	Annual Reports in Medicinal Chemistry	1998	62
16	Structure–Activity Relationships for In vitro and In vivo Toxicity	Annual Reports in Medicinal Chemistry	2006	62
17	Reducing the Risk of Drug Attrition Associated with Physicochemical Properties	Annual Reports in Medicinal Chemistry	2010	60
18	Chapter 26. Approaches to the Discovery of Non-Peptide Ligands for Peptide Receptors and Peptidases	Annual Reports in Medicinal Chemistry	1989	59
19	Chapter 28 Synthetic Approaches to Anthracycline Antibiotics	Annual Reports in Medicinal Chemistry	1979	57
20	Chapter 14. HIV Protease Inhibitors	Annual Reports in Medicinal Chemistry	1994	57
21	Chapter 28. Novel Inhibitors of the Proteasome and Their Therapeutic Use in Inflammation	Annual Reports in Medicinal Chemistry	1996	56
22	Chapter 9. Factor Xa inhibitors: Recent advances in anticoagulant agents	Annual Reports in Medicinal Chemistry	2000	56
23	Chapter 25 The Use of Isotopically Labeled Compounds in Drug Discovery	Annual Reports in Medicinal Chemistry	2009	51
24	Chapter 28. Pharmacophore Identification and Receptor Mapping	Annual Reports in Medicinal Chemistry	1980	50
25	Chapter 9. Anticoagulants: Thrombin and Factor Xa Inhibitors	Annual Reports in Medicinal Chemistry	1999	49
26	Chapter 30 Prodrugs and Site-Specific Chemical Delivery Systems	Annual Reports in Medicinal Chemistry	1987	47
27	Chapter 28. The Intramolecular Diels-Alder Reaction in Organic Synthesis	Annual Reports in Medicinal Chemistry	1974	45
28	Chapter 24. Platelet Activating Factor (PAF), A Novel Type of Phospholipid with Diverse Biological Properties	Annual Reports in Medicinal Chemistry	1982	44
29	Chapter 29. Forskolin and Adenylate Cyclase: New Opportunities in Drug Design	Annual Reports in Medicinal Chemistry	1984	44
30	Chapter 24. Inhibition of Matrix Metalloproteinases.	Annual Reports in Medicinal Chemistry	1996	43
31	Chapter 35. Pharmaceutical productivity — the imperative for new paradigms	Annual Reports in Medicinal Chemistry	2003	39
32	Chapter 6. Interoceptive Discriminative Stimuli in the Development of CNS Drugs and a Case of an Animal Model of Anxiety	Annual Reports in Medicinal Chemistry	1980	38
33	Chapter 24. Peptide Conformation and Biological Activity	Annual Reports in Medicinal Chemistry	1978	37
34	Chapter 29 Pharmacophoric Pattern Searching and Receptor Mapping	Annual Reports in Medicinal Chemistry	1979	37
35	Chapter 24. Neutrophil Elastase	Annual Reports in Medicinal Chemistry	1985	37
36	Chapter 9. Glycoprotein IIb IIIa Antagonists	Annual Reports in Medicinal Chemistry	1993	37
37	Defining Neuropharmacokinetic Parameters in CNS Drug Discovery to Determine Cross-Species Pharmacologic Exposure–Response Relationships	Annual Reports in Medicinal Chemistry	2010	37
38	Chapter 7. Anglotensln / Renln Modulators	Annual Reports in Medicinal Chemistry	1992	36
39	Thrombosis and Coagulation	Annual Reports in Medicinal Chemistry	1998	36
40	Chapter 4 Recent Advances in Drug Discovery of Histamine H3 Antagonists	Annual Reports in Medicinal Chemistry	2007	36
41	Contrasting the Gastrointestinal Tracts of Mammals: Factors that Influence Absorption	Annual Reports in Medicinal Chemistry	2008	36
42	Chapter 30. Oligonucleotide Inhibitors of Gene Expression in Living Cells: New Opportunities in Drug Design	Annual Reports in Medicinal Chemistry	1988	35
43	Chapter 15. Chemotherapy of Malaria	Annual Reports in Medicinal Chemistry	1996	35
44	Chapter 8. Anticoagulants: Inhibitors of thrombin and factor Xa	Annual Reports in Medicinal Chemistry	2001	35
45	Chapter 32. The use of bioisosteric groups in lead optimization	Annual Reports in Medicinal Chemistry	2003	35
46	Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy	Annual Reports in Medicinal Chemistry	2006	35
47	High-Throughput Screening	Annual Reports in Medicinal Chemistry	2017	35
48	Chapter 9. Potassium Channel Openers	Annual Reports in Medicinal Chemistry	1995	34
49	Chapter 25. The Polyether Antibiotics: Monocarboxylic acid ionophores	Annual Reports in Medicinal Chemistry	1975	33
50	β3 Adrenergic Receptor Agonists for the Treatment of Obesity	Annual Reports in Medicinal Chemistry	1998	33

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