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Top Articles

1Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings)CNS Neuroscience and Therapeutics2013486
2Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and TreatmentCNS Neuroscience and Therapeutics2017390
3REVIEW: Curcumin and Alzheimer's DiseaseCNS Neuroscience and Therapeutics2010367
4The Pharmacology of Lysergic Acid Diethylamide: A ReviewCNS Neuroscience and Therapeutics2008351
5A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?CNS Neuroscience and Therapeutics2011309
6Dopamine and Oxytocin Interactions Underlying Behaviors: Potential Contributions to Behavioral DisordersCNS Neuroscience and Therapeutics2010283
7Post‐Traumatic Stress Disorder in CanadaCNS Neuroscience and Therapeutics2008274
8Stress and the Microbiota–Gut–Brain Axis in Visceral Pain: Relevance to Irritable Bowel SyndromeCNS Neuroscience and Therapeutics2016262
9The Use of a Synthetic Cannabinoid in the Management of Treatment‐Resistant Nightmares in Posttraumatic Stress Disorder (PTSD)CNS Neuroscience and Therapeutics2009250
10Vilazodone: A 5‐HT1A Receptor Agonist/Serotonin Transporter Inhibitor for the Treatment of Affective DisordersCNS Neuroscience and Therapeutics2009248
11REVIEW: Neurosyphilis: A Historical Perspective and ReviewCNS Neuroscience and Therapeutics2010243
12Brain structure alterations in depression: Psychoradiological evidenceCNS Neuroscience and Therapeutics2018236
13Excessive Autophagy Contributes to Neuron Death in Cerebral IschemiaCNS Neuroscience and Therapeutics2012235
14Neurological manifestations in COVID‐19 caused by SARS‐CoV‐2CNS Neuroscience and Therapeutics2020234
15Altered Processing of Contextual Information during Fear Extinction in PTSD: An fMRI StudyCNS Neuroscience and Therapeutics2011232
16Inhibition of ferroptosis attenuates tissue damage and improves long‐term outcomes after traumatic brain injury in miceCNS Neuroscience and Therapeutics2019226
17The Experimental and Clinical Pharmacology of Propofol, an Anesthetic Agent with Neuroprotective PropertiesCNS Neuroscience and Therapeutics2008218
18Peripheral inflammation and blood–brain barrier disruption: effects and mechanismsCNS Neuroscience and Therapeutics2021214
19Tight Junction in Blood‐Brain Barrier: An Overview of Structure, Regulation, and Regulator SubstancesCNS Neuroscience and Therapeutics2012213
20Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF‐κB signaling pathwayCNS Neuroscience and Therapeutics2019213
21B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalaminCNS Neuroscience and Therapeutics2020210
22REVIEW: Oxytocin: Crossing the Bridge between Basic Science and PharmacotherapyCNS Neuroscience and Therapeutics2010209
23The Antiapoptotic Activity of Melatonin in Neurodegenerative DiseasesCNS Neuroscience and Therapeutics2009205
24Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson DiseasesCNS Neuroscience and Therapeutics2008204
25Machine learning in major depression: From classification to treatment outcome predictionCNS Neuroscience and Therapeutics2018199
26Clioquinol: Review of its Mechanisms of Action and Clinical Uses in Neurodegenerative DisordersCNS Neuroscience and Therapeutics2012196
27The Role of Tau in Alzheimer's Disease and Related DisordersCNS Neuroscience and Therapeutics2011195
28BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in StrokeCNS Neuroscience and Therapeutics2014194
29Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)‐Induced Oxidative Stress to Rescue Postnatal Rat BrainCNS Neuroscience and Therapeutics2017189
30Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasureCNS Neuroscience and Therapeutics2019186
31Astrocyte morphology: Diversity, plasticity, and role in neurological diseasesCNS Neuroscience and Therapeutics2019186
32All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2High ReceptorsCNS Neuroscience and Therapeutics2011185
33A brain network model for depression: From symptom understanding to disease interventionCNS Neuroscience and Therapeutics2018184
34Seizures and Epilepsy in Alzheimer's DiseaseCNS Neuroscience and Therapeutics2012181
35Cannabidiol: A Promising Drug for Neurodegenerative Disorders?CNS Neuroscience and Therapeutics2009179
36The neuroprotective effects of caffeine in neurodegenerative diseasesCNS Neuroscience and Therapeutics2017177
37Oxytocin Levels in Social Anxiety DisorderCNS Neuroscience and Therapeutics2008174
38RESEARCH: Cognitive Rehabilitation for Bipolar Disorder: An Open Trial for Employed Patients with Residual Depressive SymptomsCNS Neuroscience and Therapeutics2010171
39Acetylcholine–Dopamine Interactions in the Pathophysiology and Treatment of CNS DisordersCNS Neuroscience and Therapeutics2010164
40Involvement of Inflammasome Activation in Lipopolysaccharide‐induced Mice Depressive‐like BehaviorsCNS Neuroscience and Therapeutics2014160
41Amyloid β, Glutamate, Excitotoxicity in Alzheimer's Disease: Are We on the Right Track?CNS Neuroscience and Therapeutics2013159
42Ketamine and Peripheral InflammationCNS Neuroscience and Therapeutics2013158
43Biomarkers for the Clinical Differential Diagnosis in Traumatic Brain Injury-A Systematic ReviewCNS Neuroscience and Therapeutics2013157
44Antipsychotic Occupancy of Dopamine Receptors in SchizophreniaCNS Neuroscience and Therapeutics2011154
45A Double‐Edged Sword with Therapeutic Potential: An Updated Role of Autophagy in Ischemic Cerebral InjuryCNS Neuroscience and Therapeutics2012153
46Surgery Upregulates High Mobility Group Box‐1 and Disrupts the Blood–Brain Barrier causing Cognitive Dysfunction in Aged RatsCNS Neuroscience and Therapeutics2012152
47Mechanisms of Efficacy of CBT for Cambodian Refugees with PTSD: Improvement in Emotion Regulation and Orthostatic Blood Pressure ResponseCNS Neuroscience and Therapeutics2009147
48Mechanisms and roles of mitophagy in neurodegenerative diseasesCNS Neuroscience and Therapeutics2019145
49Dopamine and Glutamate in Huntington's Disease: A Balancing ActCNS Neuroscience and Therapeutics2010143
50Adenosine–Dopamine Interactions in the Pathophysiology and Treatment of CNS DisordersCNS Neuroscience and Therapeutics2010141