| # | Title | Journal | Year | Citations |
|---|
| 1 | The problem of synergism and antagonism of combined drugs | Arzneimittelforschung | 1953 | 516 |
| 2 | Effect of cilostazol on platelet aggregation and experimental thrombosis | Arzneimittelforschung | 1985 | 215 |
| 3 | The inhibitory effect of fentanyl and other morphine-like analgesics on the warm water induced tail withdrawl reflex in rats | Arzneimittelforschung | 1963 | 209 |
| 4 | Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs | Arzneimittelforschung | 1983 | 187 |
| 5 | Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids | Arzneimittelforschung | 1988 | 185 |
| 6 | Free radical scavenging activity of curcuminoids | Arzneimittelforschung | 1996 | 166 |
| 7 | IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTIC DRUGS (MAJOR TRANQUILLIZERS) FROM ANIMAL DATA?I. "NEUROLEPTIC ACTIVITY SPECTRA" FOR RATS | Arzneimittelforschung | 1965 | 150 |
| 8 | Influence of tramadol on neurotransmitter systems of the rat brain | Arzneimittelforschung | 1996 | 149 |
| 9 | Pharmacokinetics and metabolism of gabapentin in rat, dog and man | Arzneimittelforschung | 1986 | 146 |
| 10 | Blood Pressure Lowering Effect of an Olive Leaf Extract {Olea europaed) in L-NAME Induced Hypertension in Rats | Arzneimittelforschung | 2002 | 122 |
| 11 | Influence of alpha-lipoic acid on intracellular glutathione in vitro and in vivo | Arzneimittelforschung | 1992 | 115 |
| 12 | Intrinsic and Acquired Drug Resistance in Malignant Tumors | Arzneimittelforschung | 2008 | 109 |
| 13 | Antiulcerogenic Effect of Some Gastrointestinally Acting Plant Extracts and their Combination | Arzneimittelforschung | 2001 | 108 |
| 14 | Microglia, the first line of defence in brain pathologies | Arzneimittelforschung | 1995 | 108 |
| 15 | Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine | Arzneimittelforschung | 1968 | 107 |
| 16 | Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys | Arzneimittelforschung | 1997 | 107 |
| 17 | In vivo and in vitro experiments on the effects of praziquantel on Schistosoma mansoni. A light and electron microscopic study | Arzneimittelforschung | 1981 | 106 |
| 18 | Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid | Arzneimittelforschung | 1995 | 106 |
| 19 | Ginkgo biloba Special Extract in Dementia with Neuropsychiatric Features | Arzneimittelforschung | 2007 | 99 |
| 20 | Eulipidemic Effects of Berberine Administered Alone or in Combination with Other Natural Cholesterol-lowering Agents | Arzneimittelforschung | 2007 | 97 |
| 21 | Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide | Arzneimittelforschung | 1979 | 96 |
| 22 | Absorption, Distribution, Metabolism and Excretion of Glucosamine Sulfate | Arzneimittelforschung | 2001 | 95 |
| 23 | Investigations into the Mechanism of Action of the New Anticonvulsant Retigabine - Interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels | Arzneimittelforschung | 2000 | 92 |
| 24 | Effect of Sch 55700, a Humanized Monoclonal Antibody to Human Interleukin-5, on Eosinophilic Responses and Bronchial Hyperreactivity | Arzneimittelforschung | 1999 | 91 |
| 25 | Cholesterol-lowering Properties and Safety of Chitosan | Arzneimittelforschung | 2002 | 90 |
| 26 | The positive inotropic-acting forskolin, a potent adenylate cyclase activator | Arzneimittelforschung | 1981 | 90 |
| 27 | Efficacy of Artichoke Dry Extract in Patients with Hyperlipoproteinemia | Arzneimittelforschung | 2000 | 89 |
| 28 | A 1,4-benzodiazepine, temazepam (K 3917), its effect on some psychological parameters of sleep and behaviour | Arzneimittelforschung | 1975 | 87 |
| 29 | Efficacy and Safety of Oral Betaine Glucuronate in Non-alcoholic Steatohepatitis | Arzneimittelforschung | 2000 | 85 |
| 30 | The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene | Arzneimittelforschung | 1978 | 84 |
| 31 | Preclinical Pharmacology of Desloratadine, a Selective and Nonsedating Histamine H1 Receptor Antagonist | Arzneimittelforschung | 2000 | 83 |
| 32 | The Preventive Oral Supplementation of a Selenium Nanoparticle-enriched Probiotic Increases the Immune Response and Lifespan of 4T1 Breast Cancer Bearing Mice | Arzneimittelforschung | 2012 | 82 |
| 33 | Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents | Arzneimittelforschung | 1975 | 81 |
| 34 | Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance | Arzneimittelforschung | 1993 | 80 |
| 35 | Oxygen species scavenging activity of phenolic extracts from hawthorn fresh plant organs and pharmaceutical preparations | Arzneimittelforschung | 1996 | 80 |
| 36 | Effects of pioglitazone on glucose and lipid metabolism in normal and insulin resistant animals | Arzneimittelforschung | 1990 | 78 |
| 37 | Structure/histotoxicity relationship of parenteral iron preparations | Arzneimittelforschung | 1992 | 77 |
| 38 | Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats | Arzneimittelforschung | 1967 | 77 |
| 39 | Tramadol — the Impact of its Pharmacokinetic and Pharmacodynamic Properties on the Clinical Management of Pain | Arzneimittelforschung | 2003 | 76 |
| 40 | Nigella sativa L. Oil Protects against Induced Hepatotoxicity and Improves Serum Lipid Profile in Rats | Arzneimittelforschung | 2000 | 75 |
| 41 | Comparison of the inhibitory effects of cilostazol, acetylsalicylic acid and ticlopidine on platelet functions ex vivo. Randomized, double-blind cross-over study | Arzneimittelforschung | 1987 | 73 |
| 42 | Biochemical and pharmacokinetic aspects of oral treatment with chondroitin sulfate | Arzneimittelforschung | 1995 | 72 |
| 43 | Pharmacological profile of a novel synthetic inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Arzneimittelforschung | 1997 | 72 |
| 44 | Nitric Oxide-independent Activation of Soluble Guanylate Cyclase by BAY 60-2770 in Experimental Liver Fibrosis | Arzneimittelforschung | 2008 | 71 |
| 45 | Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration | Arzneimittelforschung | 1977 | 70 |
| 46 | Impairment of macrophage eicosanoid and nitric oxide production by an alkaloid from Sinomenium acutum | Arzneimittelforschung | 1994 | 70 |
| 47 | Melatonergic Drugs in Clinical Practice | Arzneimittelforschung | 2008 | 69 |
| 48 | Efficacy and tolerability of memantine in patients with dementia syndrome. A double-blind, placebo controlled trial | Arzneimittelforschung | 1991 | 69 |
| 49 | Efficacy and Tolerability of a Fluid Extract Combination of Thyme Herb and Ivy Leaves and Matched Placebo in Adults Suffering from Acute Bronchitis with Productive Cough | Arzneimittelforschung | 2006 | 67 |
| 50 | Localization and function of the D3 dopamine receptor | Arzneimittelforschung | 1992 | 66 |
