5.5(top 2%)
Impact Factor
5.8(top 2%)
extended IF
90(top 4%)
H-Index
1.4K
authors
1.8K
papers
47.1K
citations
4.5K
citing journals
35.7K
citing authors

Most Cited Articles of Expert Opinion on Drug Metabolism and Toxicology

TitleYearCitations
Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction2006948
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily2008508
The Simcyp population-based ADME simulator2009375
Caco-2 cell permeability assays to measure drug absorption2005306
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily2008286
The Caco-2 cell monolayer: usefulness and limitations2008268
Antisense oligonucleotide pharmacokinetics and metabolism2009217
Zebrafish assays for drug toxicity screening2006212
Species differences in drug transporters and implications for translating preclinical findings to humans2013192
Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges2008186
Cytochrome P450 variations in different ethnic populations2012179
Minimising the potential for metabolic activation in drug discovery2005170
Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs2009167
ABCG2: structure, function and role in drug response2008166
The effect of chronic renal failure on drug metabolism and transport2008164
Toxicity of MRI and CT contrast agents2009157
The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human2012156
Glutathione S-transferases: an overview in cancer research2010155
Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies2006153
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition2006152
Role of CAR and PXR in xenobiotic sensing and metabolism2012146
Whole-body physiologically based pharmacokinetic models2007143
Intestinal efflux transporters and drug absorption2008142
In vitro models of the human epithelial airway barrier to study the toxic potential of particulate matter2008140
The rise of PAMPA2005140