# | Title | Journal | Year | Citations |
---|
1 | Matrigel: Basement membrane matrix with biological activity | Seminars in Cancer Biology | 2005 | 1,318 |
2 | Immune evasion in cancer: Mechanistic basis and therapeutic strategies | Seminars in Cancer Biology | 2015 | 1,122 |
3 | The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues | Seminars in Cancer Biology | 1999 | 1,044 |
4 | Macrophage polarization in tumour progression | Seminars in Cancer Biology | 2008 | 1,026 |
5 | The c-Myc target gene network | Seminars in Cancer Biology | 2006 | 989 |
6 | The role of angiogenesis in tumor growth | Seminars in Cancer Biology | 1992 | 891 |
7 | Cancer stem cells and epithelial–mesenchymal transition: Concepts and molecular links | Seminars in Cancer Biology | 2012 | 781 |
8 | Regulation ofp53downstream genes | Seminars in Cancer Biology | 1998 | 756 |
9 | Epidemiology of nasopharyngeal carcinoma | Seminars in Cancer Biology | 2002 | 751 |
10 | 14-3-3 proteins: A historic overview | Seminars in Cancer Biology | 2006 | 716 |
11 | Pyruvate kinase type M2 and its role in tumor growth and spreading | Seminars in Cancer Biology | 2005 | 691 |
12 | Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression | Seminars in Cancer Biology | 2006 | 690 |
13 | The significance of cancer cell expression of the chemokine receptor CXCR4 | Seminars in Cancer Biology | 2004 | 687 |
14 | The p53–Mdm2 module and the ubiquitin system | Seminars in Cancer Biology | 2003 | 665 |
15 | Matrix metalloproteinases in tumor invasion and metastasis | Seminars in Cancer Biology | 2000 | 656 |
16 | PI3K/Akt/mTOR inhibitors in cancer: At the bench and bedside | Seminars in Cancer Biology | 2019 | 627 |
17 | Amino acid transporters ASCT2 and LAT1 in cancer: Partners in crime? | Seminars in Cancer Biology | 2005 | 608 |
18 | Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death | Seminars in Cancer Biology | 1993 | 595 |
19 | Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion | Seminars in Cancer Biology | 2010 | 592 |
20 | Sorting it out: Regulation of exosome loading | Seminars in Cancer Biology | 2014 | 592 |
21 | Cancer-related inflammation: Common themes and therapeutic opportunities | Seminars in Cancer Biology | 2012 | 567 |
22 | Inflammation as a tumor promoter in cancer induction | Seminars in Cancer Biology | 2004 | 556 |
23 | Ferroptosis is a type of autophagy-dependent cell death | Seminars in Cancer Biology | 2020 | 552 |
24 | The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts | Seminars in Cancer Biology | 2011 | 550 |
25 | Broad targeting of resistance to apoptosis in cancer | Seminars in Cancer Biology | 2015 | 535 |
26 | Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy | Seminars in Cancer Biology | 2018 | 534 |
27 | Environmental and chemical carcinogenesis | Seminars in Cancer Biology | 2004 | 522 |
28 | Epstein–Barr virus in the pathogenesis of NPC | Seminars in Cancer Biology | 2002 | 513 |
29 | Three-dimensional tissue culture models in cancer biology | Seminars in Cancer Biology | 2005 | 511 |
30 | Gene expression perturbation in vitro—A growing case for three-dimensional (3D) culture systems | Seminars in Cancer Biology | 2005 | 505 |
31 | Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis | Seminars in Cancer Biology | 2009 | 497 |
32 | The Myc oncoprotein as a therapeutic target for human cancer | Seminars in Cancer Biology | 2006 | 486 |
33 | MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation | Seminars in Cancer Biology | 2008 | 478 |
34 | The thioredoxin system in cancer | Seminars in Cancer Biology | 2006 | 471 |
35 | Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy | Seminars in Cancer Biology | 2009 | 471 |
36 | Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression | Seminars in Cancer Biology | 2012 | 468 |
37 | Sustained proliferation in cancer: Mechanisms and novel therapeutic targets | Seminars in Cancer Biology | 2015 | 468 |
38 | Metastatic heterogeneity of breast cancer: Molecular mechanism and potential therapeutic targets | Seminars in Cancer Biology | 2020 | 460 |
39 | VEGFs, receptors and angiogenesis | Seminars in Cancer Biology | 1999 | 438 |
40 | The angiogenic switch in carcinogenesis | Seminars in Cancer Biology | 2009 | 438 |
41 | EMT as the ultimate survival mechanism of cancer cells | Seminars in Cancer Biology | 2012 | 421 |
42 | From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy | Seminars in Cancer Biology | 2017 | 416 |
43 | Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation | Seminars in Cancer Biology | 2017 | 414 |
44 | The physiological function of drug-transporting P-glycoproteins | Seminars in Cancer Biology | 1997 | 413 |
45 | Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention | Seminars in Cancer Biology | 2006 | 410 |
46 | Regulation of cancer cell metabolism by hypoxia-inducible factor 1 | Seminars in Cancer Biology | 2009 | 410 |
47 | Tissue invasion and metastasis: Molecular, biological and clinical perspectives | Seminars in Cancer Biology | 2015 | 408 |
48 | Role of telomeres and telomerase in cancer | Seminars in Cancer Biology | 2011 | 407 |
49 | Role of the PI3K/AKT/mTOR signaling pathway in ovarian cancer: Biological and therapeutic significance | Seminars in Cancer Biology | 2019 | 394 |
50 | Critical determinants of metastasis | Seminars in Cancer Biology | 2002 | 391 |