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BMC Systems Biology
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top-articles
BMC Systems Biology
3.0
(top 20%)
impact factor
2.0K
(top 10%)
papers
65.2K
(top 5%)
citations
102
(top 5%)
h
-index
3.5
(top 10%)
impact factor
2.1K
all documents
72.2K
doc citations
165
(top 5%)
g
-index
Top Articles
#
Title
Journal
Year
Citations
1
cytoHubba: identifying hub objects and sub-networks from complex interactome
BMC Systems Biology
2014
3,371
2
COBRApy: COnstraints-Based Reconstruction and Analysis for Python
BMC Systems Biology
2013
973
3
Eigengene networks for studying the relationships between co-expression modules
BMC Systems Biology
2007
813
4
BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models
BMC Systems Biology
2010
467
5
Structural and functional analysis of cellular networks with CellNetAnalyzer
BMC Systems Biology
2007
454
6
Connecting extracellular metabolomic measurements to intracellular flux states in yeast
BMC Systems Biology
2009
391
7
Understanding network concepts in modules
BMC Systems Biology
2007
385
8
HINT: High-quality protein interactomes and their applications in understanding human disease
BMC Systems Biology
2012
366
9
Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii
BMC Systems Biology
2009
351
10
TIGRESS: Trustful Inference of Gene REgulation using Stability Selection
BMC Systems Biology
2012
338
11
Prioritization of disease microRNAs through a human phenome-microRNAome network
BMC Systems Biology
2010
335
12
OptFlux: an open-source software platform for in silico metabolic engineering
BMC Systems Biology
2010
321
13
Network target for screening synergistic drug combinations with application to traditional Chinese medicine
BMC Systems Biology
2011
309
14
From correlation to causation networks: a simple approximate learning algorithm and its application to high-dimensional plant gene expression data
BMC Systems Biology
2007
304
15
Data integration in the era of omics: current and future challenges
BMC Systems Biology
2014
300
16
Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces
BMC Systems Biology
2010
290
17
Identification of functional modules using network topology and high-throughput data
BMC Systems Biology
2007
267
18
Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data
BMC Systems Biology
2011
262
19
Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited
BMC Systems Biology
2010
255
20
An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks
BMC Systems Biology
2017
253
21
Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ 661 and proposing alternative drug targets
BMC Systems Biology
2007
246
22
Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance
BMC Systems Biology
2009
242
23
Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
BMC Systems Biology
2012
239
24
A review of imaging techniques for systems biology
BMC Systems Biology
2008
235
25
A systematic analysis of FDA-approved anticancer drugs
BMC Systems Biology
2017
235
26
Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis
BMC Systems Biology
2007
234
27
Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer
BMC Systems Biology
2014
233
28
Walking the interactome to identify human miRNA-disease associations through the functional link between miRNA targets and disease genes
BMC Systems Biology
2013
227
29
A general co-expression network-based approach to gene expression analysis: comparison and applications
BMC Systems Biology
2010
226
30
Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma
BMC Systems Biology
2010
223
31
Extended local similarity analysis (eLSA) of microbial community and other time series data with replicates
BMC Systems Biology
2011
223
32
targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis
BMC Systems Biology
2008
222
33
A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: i JN746 as a cell factory
BMC Systems Biology
2008
222
34
Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility
BMC Systems Biology
2008
221
35
Optimization in computational systems biology
BMC Systems Biology
2008
218
36
Metabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach
BMC Systems Biology
2011
215
37
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
BMC Systems Biology
2009
212
38
Reproducible computational biology experiments with SED-ML - The Simulation Experiment Description Markup Language
BMC Systems Biology
2011
211
39
A new essential protein discovery method based on the integration of protein-protein interaction and gene expression data
BMC Systems Biology
2012
211
40
Global dynamic optimization approach to predict activation in metabolic pathways
BMC Systems Biology
2014
211
41
The Cell Collective: Toward an open and collaborative approach to systems biology
BMC Systems Biology
2012
199
42
CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms
BMC Systems Biology
2012
198
43
OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains
BMC Systems Biology
2010
188
44
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
BMC Systems Biology
2009
187
45
Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase
BMC Systems Biology
2010
184
46
Low-complexity regions within protein sequences have position-dependent roles
BMC Systems Biology
2010
181
47
BindN+ for accurate prediction of DNA and RNA-binding residues from protein sequence features
BMC Systems Biology
2010
177
48
Snazer: the simulations and networks analyzer
BMC Systems Biology
2010
175
49
The diversity and evolution of cell cycle regulation in alpha-proteobacteria: a comparative genomic analysis
BMC Systems Biology
2010
175
50
Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling
BMC Systems Biology
2010
174
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