6.6(top 5%)
impact factor
11.4K(top 2%)
papers
548.7K(top 1%)
citations
217(top 1%)
h-index
6.9(top 5%)
extended IF
18.0K
all documents
735.1K
doc citations
343(top 1%)
g-index

Top Articles

#TitleJournalYearCitations
1Predicting effective microRNA target sites in mammalian mRNAsELife20156,037
2The MR-Base platform supports systematic causal inference across the human phenomeELife20184,436
3New tools for automated high-resolution cryo-EM structure determination in RELION-3ELife20184,280
4RNA-programmed genome editing in human cellsELife20131,884
5Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virusELife20121,693
6The Human Cell AtlasELife20171,677
7Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritisELife20131,575
8The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictusELife20151,513
9Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosisELife20141,439
10The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modificationsELife20201,304
11Escape from neutralizing antibodies by SARS-CoV-2 spike protein variantsELife20201,290
12An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sitesELife20171,246
13Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage developmentELife20171,077
14A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in miceELife20181,026
15Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 deliveryELife20141,008
16Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3ELife20211,002
17Collaboration gets the most out of softwareELife2013950
18Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2ELife2016936
19Consolidation alters motor sequence-specific distributed representationsELife2019908
20YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAsELife2017889
21SARS-CoV-2 (COVID-19) by the numbersELife2020880
22Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesisELife2014875
23Cohabiting family members share microbiota with one another and with their dogsELife2013834
24cisTEM, user-friendly software for single-particle image processingELife2018827
25Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPasesELife2016818
26Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6ELife2015791
27Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolismELife2016721
28A connectome and analysis of the adult Drosophila central brainELife2020712
29Concerning RNA-guided gene drives for the alteration of wild populationsELife2014674
30Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activationELife2016672
31Unprecedented genomic diversity of RNA viruses in arthropods reveals the ancestry of negative-sense RNA virusesELife2015657
32CaImAn an open source tool for scalable calcium imaging data analysisELife2019641
33In vitro generation of human pluripotent stem cell derived lung organoidsELife2015629
34Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plantsELife2021628
35Distinct stages in stress granule assembly and disassemblyELife2016627
36Multiple knockout mouse models reveal lincRNAs are required for life and brain developmentELife2013626
37Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary informationELife2014590
38Sampling the conformational space of the catalytic subunit of human γ-secretaseELife2015571
39Pharmacological brake-release of mRNA translation enhances cognitive memoryELife2013571
40Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteinsELife2017563
41A consensus guide to capturing the ability to inhibit actions and impulsive behaviors in the stop-signal taskELife2019541
42A large field of view two-photon mesoscope with subcellular resolution for in vivo imagingELife2016540
43Evolutionary dynamics of cancer in response to targeted combination therapyELife2013528
44Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrateELife2016516
45Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exonsELife2014507
46How open science helps researchers succeedELife2016506
47Global, quantitative and dynamic mapping of protein subcellular localizationELife2016502
48Chemical activation of the mechanotransduction channel Piezo1ELife2015498
49Fast transient networks in spontaneous human brain activityELife2014496
50The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1ELife2014496