Pharmaceutical Development and Technology

2.9(top 20%)

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2.3K(top 10%)

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40.0K(top 10%)

citations

68(top 10%)

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3.0(top 20%)

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2.5K

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41.9K

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95(top 10%)

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Top Articles

#	Title	Journal	Year	Citations
1	Protein Stability During Freezing: Separation of Stresses and Mechanisms of Protein Stabilization	Pharmaceutical Development and Technology	2007	368
2	Micron‐Size Drug Particles: Common and Novel Micronization Techniques	Pharmaceutical Development and Technology	2004	284
3	Mucoadhesive DL-Lactide/Glycolide Copolymer Nanospheres Coated with Chitosan to Improve Oral Delivery of Elcatonin	Pharmaceutical Development and Technology	2000	217
4	The Effect of Operating and Formulation Variables on the Morphology of Spray-Dried Protein Particles	Pharmaceutical Development and Technology	1997	206
5	Stabilization of Pharmaceuticals to Oxidative Degradation	Pharmaceutical Development and Technology	2002	206
6	A proposal for a drug product Manufacturing Classification System (MCS) for oral solid dosage forms	Pharmaceutical Development and Technology	2015	192
7	Solventless Pharmaceutical Coating Processes: A Review	Pharmaceutical Development and Technology	2007	170
8	Performance of Sonication and Microfluidization for Liquid–Liquid Emulsification	Pharmaceutical Development and Technology	1999	162
9	Properties of Sustained-Release Tablets Prepared by Hot-Melt Extrusion	Pharmaceutical Development and Technology	1999	155
10	Rheological and mechanical properties of poloxamer mixtures as a mucoadhesive gel base	Pharmaceutical Development and Technology	2011	140
11	A biopharmaceutical classification-based Right-First-Time formulation approach to reduce human pharmacokinetic variability and project cycle time from First-In-Human to clinical Proof-Of-Concept	Pharmaceutical Development and Technology	2012	138
12	Supercritical fluid technology: a promising approach in pharmaceutical research	Pharmaceutical Development and Technology	2013	130
13	Ocular ciprofloxacin hydrochloride mucoadhesive chitosan-coated liposomes	Pharmaceutical Development and Technology	2011	123
14	Cyclodextrin-based nanosponges: effective nanocarrier for Tamoxifen delivery	Pharmaceutical Development and Technology	2013	123
15	Hydrolysis in Pharmaceutical Formulations	Pharmaceutical Development and Technology	2002	121
16	Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement	Pharmaceutical Development and Technology	2011	118
17	In Situ Salt Screening-A Useful Technique for Discovery Support and Preformulation Studies	Pharmaceutical Development and Technology	1998	117
18	Evaluation of the Nano Spray Dryer B-90 for pharmaceutical applications	Pharmaceutical Development and Technology	2011	115
19	Physical Characterization of Pharmaceutical Formulations in Frozen and Freeze-Dried Solid States: Techniques and Applications in Freeze-Drying Development	Pharmaceutical Development and Technology	2006	114
20	Deep eutectic solvents for pharmaceutical formulation and drug delivery applications	Pharmaceutical Development and Technology	2020	111
21	Why is mannitol becoming more and more popular as a pharmaceutical excipient in solid dosage forms?	Pharmaceutical Development and Technology	2014	109
22	Practical fundamentals of glass, rubber, and plastic sterile packaging systems	Pharmaceutical Development and Technology	2010	108
23	Influence of Peroxide Impurities in Povidone and Crospovidone on the Stability of Raloxifene Hydrochloride in Tablets: Identification and Control of an Oxidative Degradation Product	Pharmaceutical Development and Technology	2000	106
24	Excipients for Direct Compaction—an Update	Pharmaceutical Development and Technology	2006	105
25	PLGA micro and nanoparticles in delivery of peptides and proteins; problems and approaches	Pharmaceutical Development and Technology	2015	105
26	Enhancement of oral bioavailability of atorvastatin calcium by self-emulsifying drug delivery systems (SEDDS)	Pharmaceutical Development and Technology	2011	104
27	Dissolution Rate Enhancement by Adsorption of Poorly Soluble Drugs on Hydrophilic Silica Aerogels	Pharmaceutical Development and Technology	2005	102
28	Formulation of Proteins in Vacuum-Dried Glasses. II. Process and Storage Stability in Sugar-Free Amino Acid Systems	Pharmaceutical Development and Technology	1999	101
29	Formulation development and process analysis of drug-loaded filaments manufactured via hot-melt extrusion for 3D-printing of medicines	Pharmaceutical Development and Technology	2018	101
30	In Situ Dehydration of Carbamazepine Dihydrate: A Novel Technique to Prepare Amorphous Anhydrous Carbamazepine	Pharmaceutical Development and Technology	2000	100
31	Sonication Parameters for the Preparation of Biodegradable Nanocapsulesof Controlled Size by the Double Emulsion Method	Pharmaceutical Development and Technology	2003	100
32	Co-solvent solubilization of some poorly-soluble antidiabetic drugs	Pharmaceutical Development and Technology	2009	100
33	Improvement of Solubility and Oral Bioavailability of Rutin by Complexation with 2-Hydroxypropyl-β-cyclodextrin	Pharmaceutical Development and Technology	2000	99
34	Curcumin-containing chitosan nanoparticles as a potential mucoadhesive delivery system to the colon	Pharmaceutical Development and Technology	2013	99
35	Tamoxifen Citrate Loaded Solid Lipid Nanoparticles (SLN™): Preparation, Characterization, In Vitro Drug Release, and Pharmacokinetic Evaluation	Pharmaceutical Development and Technology	2006	94
36	Real-time assessment of critical quality attributes of a continuous granulation process	Pharmaceutical Development and Technology	2013	94
37	Polyacrylic acid polymers hydrogels intended to topical drug delivery: preparation and characterization	Pharmaceutical Development and Technology	2015	94
38	Identifying the Stable Polymorph Early in the Drug Discovery–Development Process	Pharmaceutical Development and Technology	2005	93
39	Influence of Elastic Deformation of Particles on Heckel Analysis	Pharmaceutical Development and Technology	2001	92
40	Freeze‐Drying of Mannitol–Trehalose–Sodium Chloride‐Based Formulations: The Impact of Annealing on Dry Layer Resistance to Mass Transfer and Cake Structure	Pharmaceutical Development and Technology	2004	92
41	Preparation and Characterization of Agarose Hydrogel Nanoparticles for Protein and Peptide Drug Delivery	Pharmaceutical Development and Technology	1997	89
42	Enhanced Drug Dissolution and Bulk Properties of Solid Dispersions Granulated with a Surface Adsorbent	Pharmaceutical Development and Technology	2001	89
43	Sulforaphane delivery using mPEG–PCL co-polymer nanoparticles to breast cancer cells	Pharmaceutical Development and Technology	2017	88
44	Practical Formulation and Process Development of Freeze-Dried Products	Pharmaceutical Development and Technology	2005	86
45	Quality by design approach for formulation, evaluation and statistical optimization of diclofenac-loaded ethosomes via transdermal route	Pharmaceutical Development and Technology	2015	84
46	Positively Charged Self-Emulsifying Oil Formulation for Improving Oral Bioavailability of Progesterone	Pharmaceutical Development and Technology	1996	83
47	Polymeric nanosponges as an alternative carrier for improved retention of econazole nitrate onto the skin through topical hydrogel formulation	Pharmaceutical Development and Technology	2011	83
48	Production of Eudragit Microparticles by Spray-Drying Technique: Influence of Experimental Parameters on Morphological and Dimensional Characteristics	Pharmaceutical Development and Technology	2000	82
49	Curcumin amorphous solid dispersions: the influence of intra and intermolecular bonding on physical stability	Pharmaceutical Development and Technology	2014	82
50	Multivariate analysis in the pharmaceutical industry: enabling process understanding and improvement in the PAT and QbD era	Pharmaceutical Development and Technology	2015	80

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