| # | Title | Journal | Year | Citations |
|---|
| 1 | Circadian rhythm disturbances in depression | Human Psychopharmacology | 2008 | 477 |
| 2 | Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative–antioxidative systems | Human Psychopharmacology | 2007 | 404 |
| 3 | Cannabis and anxiety: a critical review of the evidence | Human Psychopharmacology | 2009 | 398 |
| 4 | Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research | Human Psychopharmacology | 2001 | 303 |
| 5 | Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders | Human Psychopharmacology | 2001 | 293 |
| 6 | Cytokines: abnormalities in major depression and implications for pharmacological treatment | Human Psychopharmacology | 2004 | 271 |
| 7 | Antidepressants and their effect on sleep | Human Psychopharmacology | 2005 | 260 |
| 8 | Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double‐blind, randomized, placebo‐controlled study | Human Psychopharmacology | 2008 | 255 |
| 9 | Marijuana, alcohol and actual driving performance | Human Psychopharmacology | 2000 | 248 |
| 10 | Patterns of simultaneous polysubstance use in drug using university students | Human Psychopharmacology | 2006 | 230 |
| 11 | The use of ketamine as an antidepressant: a systematic review and meta‐analysis | Human Psychopharmacology | 2015 | 217 |
| 12 | A review of the role of serotonin receptors in psychiatric disorders | Human Psychopharmacology | 2000 | 211 |
| 13 | The epidemiology of pain in depression | Human Psychopharmacology | 2004 | 211 |
| 14 | Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression | Human Psychopharmacology | 2013 | 207 |
| 15 | A psychoneuroimmunological review on cytokines involved in antidepressant treatment response | Human Psychopharmacology | 2010 | 206 |
| 16 | Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects | Human Psychopharmacology | 2004 | 203 |
| 17 | Subjective hypnotic efficacy of trazodone and zolpidem in DSMIII-R primary insomnia | Human Psychopharmacology | 1998 | 200 |
| 18 | IL-6 levels decrease with SSRI treatment in patients with major depression | Human Psychopharmacology | 2005 | 196 |
| 19 | Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies | Human Psychopharmacology | 2001 | 195 |
| 20 | Application of transcranial magnetic stimulation in treatment of drug-resistant major depression-a report of two cases | Human Psychopharmacology | 1993 | 191 |
| 21 | Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury | Human Psychopharmacology | 2005 | 178 |
| 22 | Haematological toxicity of drugs used in psychiatry | Human Psychopharmacology | 2008 | 175 |
| 23 | Neurological complications of psychiatric drugs: clinical features and management | Human Psychopharmacology | 2008 | 175 |
| 24 | An overview of the clinical efficacy of mirtazapine | Human Psychopharmacology | 2002 | 172 |
| 25 | Stress reactivity: biological and subjective responses to the cold pressor and Trier Social stressors | Human Psychopharmacology | 2006 | 170 |
| 26 | The psychoneuroimmunology of depression | Human Psychopharmacology | 2009 | 167 |
| 27 | A double-blind placebo-controlled trial of milnacipran in the treatment of fibromyalgia | Human Psychopharmacology | 2004 | 164 |
| 28 | Sexual dysfunction in schizophrenia: focus on recent evidence | Human Psychopharmacology | 2008 | 158 |
| 29 | Comparative efficacy of newer hypnotic drugs for the short-term management of insomnia: a systematic review and meta-analysis | Human Psychopharmacology | 2004 | 155 |
| 30 | Transcranial magnetic stimulation (TMS) in the treatment of major depression — a pilot study | Human Psychopharmacology | 1995 | 152 |
| 31 | Factors associated with treatment nonadherence among US bipolar disorder patients | Human Psychopharmacology | 2008 | 152 |
| 32 | A review of the pharmacokinetics, tolerability and pharmacodynamics of amisulpride in healthy volunteers | Human Psychopharmacology | 2002 | 151 |
| 33 | Promoting innovation and excellence to face the rapid diffusion of Novel Psychoactive Substances in the EU: the outcomes of the ReDNet project | Human Psychopharmacology | 2013 | 151 |
| 34 | “Spiceophrenia”: a systematic overview of “Spice”‐related psychopathological issues and a case report | Human Psychopharmacology | 2013 | 150 |
| 35 | Antidepressants and memory: A review | Human Psychopharmacology | 1991 | 148 |
| 36 | How valuable are animal models in defining antidepressant activity? | Human Psychopharmacology | 2001 | 146 |
| 37 | Human psychobiology of MDMA or ‘Ecstasy’: an overview of 25 years of empirical research | Human Psychopharmacology | 2013 | 146 |
| 38 | The immunoregulatory effects of antidepressants | Human Psychopharmacology | 2001 | 144 |
| 39 | Prevalence, recognition and management of depression in primary care in Germany: the Depression 2000 study | Human Psychopharmacology | 2002 | 144 |
| 40 | Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action | Human Psychopharmacology | 2014 | 140 |
| 41 | Phenomenon of new drugs on the Internet: the case of ketamine derivative methoxetamine | Human Psychopharmacology | 2012 | 139 |
| 42 | Ecstasy abuse and dependence among adolescents and young adults: applicability and reliability of DSM-IV criteria | Human Psychopharmacology | 2001 | 138 |
| 43 | A double blind comparison of the effects of fluoxetine and amitriptyline on cognitive function in elderly depressed patients | Human Psychopharmacology | 1993 | 136 |
| 44 | Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users | Human Psychopharmacology | 2002 | 136 |
| 45 | 5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response | Human Psychopharmacology | 2000 | 135 |
| 46 | A double-blind, placebo-controlled, randomized trial ofGinkgo bilobaextract EGb 761® in a sample of cognitively intact older adults: neuropsychological findings | Human Psychopharmacology | 2002 | 134 |
| 47 | Acute, sub-acute and long-term subjective consequences of ?ecstasy? (MDMA) consumption in 430 regular users | Human Psychopharmacology | 2003 | 131 |
| 48 | Cardiac side effects of psychiatric drugs | Human Psychopharmacology | 2008 | 127 |
| 49 | Immune system inflammation in cocaine dependent individuals: implications for medications development | Human Psychopharmacology | 2012 | 124 |
| 50 | Efficacy of etifoxine compared to lorazepam monotherapy in the treatment of patients with adjustment disorders with anxiety: a double-blind controlled study in general practice | Human Psychopharmacology | 2006 | 120 |
