| # | Title | Journal | Year | Citations |
|---|
| 1 | A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA | Plasmid | 1985 | 1,125 |
| 2 | A rapid method for the identification of plasmid desoxyribonucleic acid in bacteria | Plasmid | 1978 | 1,061 |
| 3 | A multiple plasmid-containing Escherichia coli strain: Convenient source of size reference plasmid molecules | Plasmid | 1978 | 914 |
| 4 | Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression | Plasmid | 1985 | 839 |
| 5 | Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coli | Plasmid | 1984 | 768 |
| 6 | Wide host range cloning vectors: A cosmid clone bank of an Agrobacterium Ti plasmid | Plasmid | 1982 | 658 |
| 7 | Genetic Exchange between Bacteria in the Environment | Plasmid | 1999 | 597 |
| 8 | Allelic replacement in Staphylococcus aureus with inducible counter-selection | Plasmid | 2006 | 562 |
| 9 | Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli | Plasmid | 1981 | 514 |
| 10 | The functional organization of the nopaline A. tumefaciens plasmid pTiC58 | Plasmid | 1980 | 470 |
| 11 | Integration-Proficient Plasmids for Pseudomonas aeruginosa: Site-Specific Integration and Use for Engineering of Reporter and Expression Strains | Plasmid | 2000 | 459 |
| 12 | Two plasmid-determined restriction and modification systems in Streptococcus lactis | Plasmid | 1984 | 439 |
| 13 | Conditionally Replicative and Conjugative Plasmids CarryinglacZα for Cloning, Mutagenesis, and Allele Replacement in Bacteria | Plasmid | 1996 | 413 |
| 14 | Construction of a cloning site near one end of Tn917 into which foreign DNA may be inserted without affecting transposition in Bacillus subtilis or expression of the transposon-borne erm gene | Plasmid | 1984 | 398 |
| 15 | Fingerprints of Agrobacterium Ti plasmids | Plasmid | 1978 | 393 |
| 16 | An improved colony hybridization method with significantly increased sensitivity for detection of single genes | Plasmid | 1983 | 367 |
| 17 | Improvement of pCVD442, a suicide plasmid for gene allele exchange in bacteria | Plasmid | 2004 | 337 |
| 18 | Germanium and silver resistance, accumulation, and toxicity in microorganisms | Plasmid | 1992 | 325 |
| 19 | Resistance to cadmium, cobalt, zinc, and nickel in microbes | Plasmid | 1992 | 318 |
| 20 | Complete nucleotide sequence of pT181, a tetracycline-resistance plasmid from Staphylococcus aureus | Plasmid | 1983 | 310 |
| 21 | Plasmid transfer in Streptococcus faecalis: Production of multiple sex pheromones by recipients | Plasmid | 1979 | 301 |
| 22 | Octopine Ti-plasmid deletion mutants of Agrobacterium tumefaciens with emphasis on the right side of the T-region | Plasmid | 1982 | 297 |
| 23 | Determination of plasmid copy number by fluorescence densitometry | Plasmid | 1983 | 291 |
| 24 | Thermosensitive Suicide Vectors for Gene Replacement in Streptococcus suis | Plasmid | 2001 | 283 |
| 25 | Elimination of plastids during spermatogenesis and fertilization in the plant kingdom | Plasmid | 1980 | 281 |
| 26 | Heterogeneity of tetracycline resistance determinants | Plasmid | 1980 | 275 |
| 27 | Penicillinase plasmids of Staphylococcus aureus: Restriction-deletion maps | Plasmid | 1979 | 268 |
| 28 | Involvement of a plasmid in the hairy root disease of plants caused by Agrobacterium rhizogenes | Plasmid | 1979 | 262 |
| 29 | A rapid microscale technique for isolation of recombinant plasmid DNA suitable for restriction enzyme analysis | Plasmid | 1980 | 261 |
| 30 | Expansion of the IncX plasmid family for improved identification and typing of novel plasmids in drug-resistant Enterobacteriaceae | Plasmid | 2012 | 260 |
| 31 | The nucleotide sequence of pUB110: Some salient features in relation to replication and its regulation | Plasmid | 1986 | 257 |
| 32 | Correlation between specific plasmids and δ-endotoxin production in Bacillus thuringiensis | Plasmid | 1981 | 256 |
| 33 | R plasmid gene dosage effects in Escherichia coli K-12: Copy mutants of the R plasmid R1drd-19 | Plasmid | 1977 | 250 |
| 34 | Restriction map of an agropine-type Ri plasmid and its homologies with Ti plasmids | Plasmid | 1984 | 247 |
| 35 | Molecular cloning of overlapping segments of the nopaline Ti-plasmid pTiC58 as a means to restriction endonuclease mapping | Plasmid | 1980 | 245 |
| 36 | Improved Vectors for Nisin-Controlled Expression in Gram-Positive Bacteria | Plasmid | 2000 | 244 |
| 37 | Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus | Plasmid | 2003 | 238 |
| 38 | The kinetics of conjugative plasmid transmission: Fit of a simple mass action model | Plasmid | 1979 | 231 |
| 39 | Revised nomenclature for transposable genetic elements | Plasmid | 2008 | 222 |
| 40 | Partitioning of plasmid R1 in Escherichia coli, | Plasmid | 1980 | 221 |
| 41 | Nucleotide sequence analysis of a gene encoding a streptomycin/spectinomycin adenyltransferase | Plasmid | 1985 | 221 |
| 42 | Molecular, genetic, and functional analysis of the basic replicon of pVA380-1, a plasmid of oral streptococcal origin | Plasmid | 1992 | 215 |
| 43 | Bacterial resistances to inorganic mercury salts and organomercurials | Plasmid | 1992 | 210 |
| 44 | A new set of small, extrachromosomal expression vectors for Dictyostelium discoideum | Plasmid | 2009 | 209 |
| 45 | The current ICE age: Biology and evolution of SXT-related integrating conjugative elements | Plasmid | 2006 | 208 |
| 46 | pHG165: A pBR322 copy number derivative of pUC8 for cloning and expression | Plasmid | 1986 | 205 |
| 47 | Kinetoplast DNA | Plasmid | 1979 | 204 |
| 48 | Essential virulence determinants of different Yersinia species are carried on a common plasmid | Plasmid | 1981 | 204 |
| 49 | Transfer of antibiotic-resistance genes via phage-related mobile elements | Plasmid | 2015 | 200 |
| 50 | Plasmids that mobilize bacterial chromosome | Plasmid | 1979 | 196 |
