| # | Title | Journal | Year | Citations |
|---|
| 1 | Selective neuronal vulnerability to oxidative stress in the brain | Frontiers in Aging Neuroscience | 2010 | 653 |
| 2 | Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial | Frontiers in Aging Neuroscience | 2016 | 597 |
| 3 | Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA | Frontiers in Aging Neuroscience | 2015 | 592 |
| 4 | Plasticity of brain networks in a randomized intervention trial of exercise training in older adults | Frontiers in Aging Neuroscience | 2010 | 444 |
| 5 | Microglial cell dysregulation in brain aging and neurodegeneration | Frontiers in Aging Neuroscience | 2015 | 421 |
| 6 | Deep Learning in Alzheimer's Disease: Diagnostic Classification and Prognostic Prediction Using Neuroimaging Data | Frontiers in Aging Neuroscience | 2019 | 406 |
| 7 | Contribution of the D-Serine-dependent pathway to the cellular mechanisms underlying cognitive aging | Frontiers in Aging Neuroscience | 2010 | 383 |
| 8 | Random Forest Algorithm for the Classification of Neuroimaging Data in Alzheimer's Disease: A Systematic Review | Frontiers in Aging Neuroscience | 2017 | 379 |
| 9 | Mechanisms of Aβ Clearance and Degradation by Glial Cells | Frontiers in Aging Neuroscience | 2016 | 372 |
| 10 | The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma | Frontiers in Aging Neuroscience | 2017 | 348 |
| 11 | Sarcopenia and Physical Frailty: Two Sides of the Same Coin | Frontiers in Aging Neuroscience | 2014 | 338 |
| 12 | ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment? | Frontiers in Aging Neuroscience | 2017 | 332 |
| 13 | Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice | Frontiers in Aging Neuroscience | 2014 | 331 |
| 14 | The effects of intracranial volume adjustment approaches on multiple regional MRI volumes in healthy aging and Alzheimer's disease | Frontiers in Aging Neuroscience | 2014 | 322 |
| 15 | Measuring sleep quality in older adults: a comparison using subjective and objective methods | Frontiers in Aging Neuroscience | 2015 | 318 |
| 16 | A delicate balance: Iron metabolism and diseases of the brain | Frontiers in Aging Neuroscience | 2013 | 314 |
| 17 | Age-group differences in speech identification despite matched audiometrically normal hearing: contributions from auditory temporal processing and cognition | Frontiers in Aging Neuroscience | 2014 | 310 |
| 18 | Microglial Activation in Traumatic Brain Injury | Frontiers in Aging Neuroscience | 2017 | 307 |
| 19 | Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects | Frontiers in Aging Neuroscience | 2019 | 294 |
| 20 | Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications | Frontiers in Aging Neuroscience | 2018 | 285 |
| 21 | Shorter term aerobic exercise improves brain, cognition, and cardiovascular fitness in aging | Frontiers in Aging Neuroscience | 2013 | 283 |
| 22 | In Alzheimer’s Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial | Frontiers in Aging Neuroscience | 2016 | 282 |
| 23 | Hundred days of cognitive training enhance broad cognitive abilities in adulthood: findings from the COGITO study | Frontiers in Aging Neuroscience | 2010 | 281 |
| 24 | Pathology and pathogenesis of vascular cognitive impairment—a critical update | Frontiers in Aging Neuroscience | 2013 | 267 |
| 25 | Weight Loss and Malnutrition in Patients with Parkinson's Disease: Current Knowledge and Future Prospects | Frontiers in Aging Neuroscience | 2018 | 259 |
| 26 | Astrocyte Heterogeneity: Impact to Brain Aging and Disease | Frontiers in Aging Neuroscience | 2019 | 256 |
| 27 | Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration | Frontiers in Aging Neuroscience | 2013 | 255 |
| 28 | Spatial navigational strategies correlate with gray matter in the hippocampus of healthy older adults tested in a virtual maze | Frontiers in Aging Neuroscience | 2013 | 251 |
| 29 | Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer’s Disease Brain: A Review | Frontiers in Aging Neuroscience | 2018 | 249 |
| 30 | Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease | Frontiers in Aging Neuroscience | 2017 | 245 |
| 31 | Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease | Frontiers in Aging Neuroscience | 2021 | 236 |
| 32 | Six months of dance intervention enhances postural, sensorimotor, and cognitive performance in elderly without affecting cardio-respiratory functions | Frontiers in Aging Neuroscience | 2013 | 235 |
| 33 | Zinc homeostasis and neurodegenerative disorders | Frontiers in Aging Neuroscience | 2013 | 235 |
| 34 | 16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer’s Post-Mortem Brain | Frontiers in Aging Neuroscience | 2017 | 234 |
| 35 | High Cortisol and the Risk of Dementia and Alzheimer’s Disease: A Review of the Literature | Frontiers in Aging Neuroscience | 2019 | 234 |
| 36 | The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle | Frontiers in Aging Neuroscience | 2014 | 230 |
| 37 | Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities | Frontiers in Aging Neuroscience | 2019 | 228 |
| 38 | The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease | Frontiers in Aging Neuroscience | 2018 | 226 |
| 39 | Using network science to evaluate exercise-associated brain changes in older adults | Frontiers in Aging Neuroscience | 2010 | 223 |
| 40 | Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders | Frontiers in Aging Neuroscience | 2019 | 220 |
| 41 | Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain | Frontiers in Aging Neuroscience | 2019 | 220 |
| 42 | Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases | Frontiers in Aging Neuroscience | 2016 | 215 |
| 43 | “Are we ready for robots that care for us?” Attitudes and opinions of older adults toward socially assistive robots | Frontiers in Aging Neuroscience | 2015 | 214 |
| 44 | Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain | Frontiers in Aging Neuroscience | 2019 | 214 |
| 45 | Microglia Polarization From M1 to M2 in Neurodegenerative Diseases | Frontiers in Aging Neuroscience | 2022 | 212 |
| 46 | Tau Oligomers: Cytotoxicity, Propagation, and Mitochondrial Damage | Frontiers in Aging Neuroscience | 2017 | 209 |
| 47 | Molecular mechanisms of cognitive dysfunction following traumatic brain injury | Frontiers in Aging Neuroscience | 2013 | 208 |
| 48 | The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis | Frontiers in Aging Neuroscience | 2016 | 207 |
| 49 | “Is dopamine involved in Alzheimer's disease?†| Frontiers in Aging Neuroscience | 2014 | 202 |
| 50 | Deciphering the Astrocyte Reaction in Alzheimer’s Disease | Frontiers in Aging Neuroscience | 2018 | 202 |
