| # | Title | Journal | Year | Citations |
|---|
| 1 | The operation. A human cardiac transplant: an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town | South African Medical Journal | 1967 | 546 |
| 2 | Detection of Chlamydia pneumoniae in coronary arterial fatty streaks and atheromatous plaques | South African Medical Journal | 1992 | 275 |
| 3 | Establishment of a continuously growing cell line from primary carcinoma of the liver | South African Medical Journal | 1976 | 264 |
| 4 | The South African Stress and Health (SASH) study: 12-month and lifetime prevalence of common mental disorders | South African Medical Journal | 2009 | 219 |
| 5 | The World Health Organization Global Action Plan for antimicrobial resistance | South African Medical Journal | 2015 | 196 |
| 6 | Ultramarathon running and upper respiratory tract infections. An epidemiological survey | South African Medical Journal | 1983 | 186 |
| 7 | Chikungunya virus infection. A retrospective study of 107 cases | South African Medical Journal | 1983 | 178 |
| 8 | Tick-bite fever in pregnancy. A case report | South African Medical Journal | 1987 | 174 |
| 9 | Fusarium moniliforme contamination of maize in oesophageal cancer areas in Transkei | South African Medical Journal | 1988 | 165 |
| 10 | Initial burden of disease estimates for South Africa, 2000 | South African Medical Journal | 2003 | 158 |
| 11 | Long-COVID: An evolving problem with an extensive impact | South African Medical Journal | 2020 | 146 |
| 12 | Selective posterior rhizotomy for the relief of spasticity in cerebral palsy | South African Medical Journal | 1982 | 138 |
| 13 | The cytopathic effects of vervet monkey viruses | South African Medical Journal | 1963 | 138 |
| 14 | Pregnancy in a uterine scar sacculus--an unusual cause of postabortal haemorrhage. A case report | South African Medical Journal | 1978 | 132 |
| 15 | Validation of the Edinburgh Postnatal Depression Scale on a cohort of South African women | South African Medical Journal | 1998 | 132 |
| 16 | A review of 450 stabwounds of the spinal cord | South African Medical Journal | 1977 | 129 |
| 17 | A longitudinal study of asymptomatic carriers of pathogenic zymodemes of Entamoeba histolytica | South African Medical Journal | 1987 | 122 |
| 18 | Endotoxaemia in exhausted runners after a long-distance race | South African Medical Journal | 1988 | 122 |
| 19 | High prevalence of diabetes mellitus and metabolic syndrome in a South African coloured population: Baseline data of a study in Bellville, Cape Town | South African Medical Journal | 2012 | 121 |
| 20 | Prevalence of emotional, physical and sexual abuse of women in three South African provinces | South African Medical Journal | 2001 | 116 |
| 21 | National HIV incidence measures--new insights into the South African epidemic | South African Medical Journal | 2007 | 112 |
| 22 | An evaluation of the District Health Information System in rural South Africa | South African Medical Journal | 2008 | 111 |
| 23 | Rift Valley fever affecting humans in South Africa: a clinicopathological study | South African Medical Journal | 1977 | 110 |
| 24 | The epidemiology of major depression in South Africa: results from the South African stress and health study | South African Medical Journal | 2009 | 108 |
| 25 | The true clincal features of postmenopause and oöphorectomy, and their response to oestrogen therapy | South African Medical Journal | 1972 | 107 |
| 26 | Rapid scale-up of a community-based HIV treatment service: programme performance over 3 consecutive years in Guguletu, South Africa | South African Medical Journal | 2006 | 102 |
| 27 | Chloroquine phosphate treatment of chronic Chikungunya arthritis. An open pilot study | South African Medical Journal | 1984 | 101 |
| 28 | The surgical correction of chronic internal anal (sphincteric) contracture | South African Medical Journal | 1951 | 99 |
| 29 | Antenatal depression and its risk factors: An urban prevalence study in KwaZulu-Natal | South African Medical Journal | 2012 | 97 |
| 30 | Rheumatoid arthritic syndrome after chikungunya fever | South African Medical Journal | 1979 | 97 |
| 31 | Dual time-point FDG PET-CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area | South African Medical Journal | 2010 | 96 |
| 32 | Lost to follow up: contributing factors and challenges in South African patients on antiretroviral therapy | South African Medical Journal | 2007 | 96 |
| 33 | Factors associated with fatal cases of measles. A retrospective autopsy study | South African Medical Journal | 1985 | 95 |
| 34 | APRI: a simple bedside marker for advanced fibrosis that can avoid liver biopsy in patients with NAFLD/NASH | South African Medical Journal | 2011 | 94 |
| 35 | Outcomes of the South African National Antiretroviral Treatment Programme for children: the IeDEA Southern Africa collaboration | South African Medical Journal | 2009 | 93 |
| 36 | Mid-systolic clicks | South African Medical Journal | 1961 | 93 |
| 37 | Left ventricular bypass | South African Medical Journal | 1975 | 92 |
| 38 | Acute pulmonary oedema in two athletes during a 90-km running race | South African Medical Journal | 1979 | 89 |
| 39 | Tuberculosis control in South Africa: Successes, challenges and recommendations | South African Medical Journal | 2014 | 88 |
| 40 | Rift Valley fever in humans in South Africa | South African Medical Journal | 1980 | 85 |
| 41 | PMTCT from research to reality--results from a routine service | South African Medical Journal | 2004 | 85 |
| 42 | Mental health service delivery in South Africa from 2000 to 2010: one step forward, one step back | South African Medical Journal | 2011 | 84 |
| 43 | The effect of undernutrition during infancy on subsequent brain growth and intellectual development | South African Medical Journal | 1967 | 83 |
| 44 | Alcohol consumption by pregnant women in the Western Cape | South African Medical Journal | 1999 | 83 |
| 45 | Prevalence of tobacco use among adults in South Africa: Results from the first South African National Health and Nutrition Examination Survey | South African Medical Journal | 2015 | 80 |
| 46 | Impact of DDT re-introduction on malaria transmission in KwaZulu-Natal | South African Medical Journal | 2005 | 80 |
| 47 | An unusual case of human rabies thought to be of chiropteran origin | South African Medical Journal | 1971 | 79 |
| 48 | Oral hypoglycaemics in the first trimester and fetal outcome | South African Medical Journal | 1984 | 79 |
| 49 | Mortality in patients treated for tuberculous pericarditis in sub-Saharan Africa | South African Medical Journal | 2008 | 79 |
| 50 | Intimate partner piolence, health Behaviours, and chronic physical illness among South African women | South African Medical Journal | 2010 | 78 |
