# | Title | Journal | Year | Citations |
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1 | Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19 | Acta Pharmacologica Sinica | 2020 | 1,611 |
2 | Amyloid beta: structure, biology and structure-based therapeutic development | Acta Pharmacologica Sinica | 2017 | 1,094 |
3 | Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases | Acta Pharmacologica Sinica | 2009 | 890 |
4 | Engineering exosomes as refined biological nanoplatforms for drug delivery | Acta Pharmacologica Sinica | 2017 | 767 |
5 | Mesenchymal stem cells: a new trend for cell therapy | Acta Pharmacologica Sinica | 2013 | 758 |
6 | Androgen receptor: structure, role in prostate cancer and drug discovery | Acta Pharmacologica Sinica | 2015 | 602 |
7 | Botanical characteristics, pharmacological effects and medicinal components of KoreanPanax ginsengC A Meyer | Acta Pharmacologica Sinica | 2008 | 520 |
8 | Tumor necrosis factor and cancer, buddies or foes? | Acta Pharmacologica Sinica | 2008 | 514 |
9 | Understanding and targeting cancer stem cells: therapeutic implications and challenges | Acta Pharmacologica Sinica | 2013 | 506 |
10 | New knowledge of the mechanisms of sorafenib resistance in liver cancer | Acta Pharmacologica Sinica | 2017 | 475 |
11 | miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges | Acta Pharmacologica Sinica | 2018 | 418 |
12 | CB-Dock: a web server for cavity detection-guided protein–ligand blind docking | Acta Pharmacologica Sinica | 2020 | 377 |
13 | Relationship between antibacterial activity of chitosan and surface characteristics of cell wall | Acta Pharmacologica Sinica | 2004 | 357 |
14 | Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine1 | Acta Pharmacologica Sinica | 2006 | 349 |
15 | Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients | Acta Pharmacologica Sinica | 2020 | 314 |
16 | Nitric oxide: a newly discovered function on wound healing | Acta Pharmacologica Sinica | 2005 | 313 |
17 | Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action | Acta Pharmacologica Sinica | 2005 | 301 |
18 | Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics | Acta Pharmacologica Sinica | 2018 | 295 |
19 | Exosomes: new molecular targets of diseases | Acta Pharmacologica Sinica | 2018 | 292 |
20 | Application and interpretation of current autophagy inhibitors and activators | Acta Pharmacologica Sinica | 2013 | 286 |
21 | Regulation of microglial activation in stroke | Acta Pharmacologica Sinica | 2017 | 270 |
22 | Exosomal cargo-loading and synthetic exosome-mimics as potential therapeutic tools | Acta Pharmacologica Sinica | 2018 | 269 |
23 | Tools for GPCR drug discovery | Acta Pharmacologica Sinica | 2012 | 267 |
24 | Morinda citrifolia (Noni): a literature review and recent advances in Noni research | Acta Pharmacologica Sinica | 2002 | 265 |
25 | Protein tyrosine phosphatases as potential therapeutic targets | Acta Pharmacologica Sinica | 2014 | 260 |
26 | The role of BDNF in depression on the basis of its location in the neural circuitry | Acta Pharmacologica Sinica | 2011 | 257 |
27 | Arterial stiffness: a brief review | Acta Pharmacologica Sinica | 2010 | 253 |
28 | Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase | Acta Pharmacologica Sinica | 2008 | 248 |
29 | Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases | Acta Pharmacologica Sinica | 2018 | 246 |
30 | Why should autophagic flux be assessed? | Acta Pharmacologica Sinica | 2013 | 245 |
31 | Gold nanoparticles in cancer therapy | Acta Pharmacologica Sinica | 2011 | 243 |
32 | Computational drug discovery | Acta Pharmacologica Sinica | 2012 | 238 |
33 | Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system | Acta Pharmacologica Sinica | 2017 | 236 |
34 | Laboratory animals as surrogate models of human obesity | Acta Pharmacologica Sinica | 2012 | 224 |
35 | Comparison of the pharmacological effects ofPanax ginsengandPanax quinquefolium | Acta Pharmacologica Sinica | 2008 | 223 |
36 | Immunomodulatory effects of lactoferrin | Acta Pharmacologica Sinica | 2014 | 223 |
37 | Cross-talk between calcium and reactive oxygen species signaling | Acta Pharmacologica Sinica | 2006 | 216 |
38 | Flavonoid-membrane interactions: possible consequences for biological effects of some polyphenolic compounds1 | Acta Pharmacologica Sinica | 2006 | 207 |
39 | Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease | Acta Pharmacologica Sinica | 2011 | 206 |
40 | Are isothiocyanates potential anti-cancer drugs? | Acta Pharmacologica Sinica | 2009 | 205 |
41 | Small molecule inhibitors targeting the PD-1/PD-L1 signaling pathway | Acta Pharmacologica Sinica | 2021 | 203 |
42 | Leptin, cardiovascular diseases and type 2 diabetes mellitus | Acta Pharmacologica Sinica | 2018 | 197 |
43 | Inflammatory responses in hypoxic ischemic encephalopathy | Acta Pharmacologica Sinica | 2013 | 196 |
44 | Pulmonary delivery of nanoparticle chemotherapy for the treatment of lung cancers: challenges and opportunities | Acta Pharmacologica Sinica | 2017 | 196 |
45 | Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment | Acta Pharmacologica Sinica | 2015 | 193 |
46 | Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms | Acta Pharmacologica Sinica | 2004 | 190 |
47 | Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system | Acta Pharmacologica Sinica | 2009 | 186 |
48 | Molecular mechanism and regulation of autophagy1 | Acta Pharmacologica Sinica | 2005 | 183 |
49 | Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation | Acta Pharmacologica Sinica | 2005 | 182 |
50 | Discovery and development of sulforaphane as a cancer chemopreventive phytochemical | Acta Pharmacologica Sinica | 2007 | 182 |