Chemical Biology and Drug Design

2.7(top 20%)

impact factor

2.8K(top 10%)

papers

54.5K(top 5%)

citations

80(top 10%)

h-index

2.8(top 20%)

impact factor

3.7K

all documents

57.6K

doc citations

138(top 5%)

g-index

Top Articles

#	Title	Journal	Year	Citations
1	The Future of Peptide‐based Drugs	Chemical Biology and Drug Design	2013	1,483
2	Inhibition of Amyloid Fibril Formation by Polyphenols: Structural Similarity and Aromatic Interactions as a Common Inhibition Mechanism	Chemical Biology and Drug Design	2006	859
3	The Structure of Glycosaminoglycans and their Interactions with Proteins	Chemical Biology and Drug Design	2008	820
4	New Method for Fast and Accurate Binding-site Identification and Analysis	Chemical Biology and Drug Design	2007	656
5	Use of an Induced Fit Receptor Structure in Virtual Screening	Chemical Biology and Drug Design	2006	550
6	PHASE: A Novel Approach to Pharmacophore Modeling and 3D Database Searching	Chemical Biology and Drug Design	2006	520
7	Circular Dichroism Techniques: Biomolecular and Nanostructural Analyses‐ A Review	Chemical Biology and Drug Design	2009	483
8	Anti‐Inflammatory Property of n‐Hexadecanoic Acid: Structural Evidence and Kinetic Assessment	Chemical Biology and Drug Design	2012	400
9	Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity	Chemical Biology and Drug Design	2009	379
10	Probing the α‐Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis	Chemical Biology and Drug Design	2010	351
11	Vicinal Diamino Functionalities as Privileged Structural Elements in Biologically Active Compounds and Exploitation of their Synthetic Chemistry	Chemical Biology and Drug Design	2006	332
12	Structure–activity Relationships of Amyloid Beta‐aggregation Inhibitors Based on Curcumin: Influence of Linker Length and Flexibility	Chemical Biology and Drug Design	2007	282
13	1,3,4‐Thiadiazole and its Derivatives: A Review on Recent Progress in Biological Activities	Chemical Biology and Drug Design	2013	263
14	Antibiotic Adjuvants: Diverse Strategies for Controlling Drug‐Resistant Pathogens	Chemical Biology and Drug Design	2015	245
15	Comprehensive Review in Current Developments of Benzimidazole‐Based Medicinal Chemistry	Chemical Biology and Drug Design	2015	243
16	Two‐ and Three‐dimensional Rings in Drugs	Chemical Biology and Drug Design	2014	235
17	Structural Mechanism of the Pan‐BCR‐ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance	Chemical Biology and Drug Design	2011	231
18	Homology modeling in drug discovery: Overview, current applications, and future perspectives	Chemical Biology and Drug Design	2019	229
19	Antibody‐Drug Conjugates for the Treatment of Cancer	Chemical Biology and Drug Design	2013	193
20	Characteristics of flavonoids as potent MERS‐CoV 3C‐like protease inhibitors	Chemical Biology and Drug Design	2019	191
21	In Vitro Inhibition of Human Carbonic Anhydrase I and II Isozymes with Natural Phenolic Compounds	Chemical Biology and Drug Design	2011	170
22	Chemogenetic Analysis of Human Protein Methyltransferases	Chemical Biology and Drug Design	2011	167
23	Compensating Enthalpic and Entropic Changes Hinder Binding Affinity Optimization	Chemical Biology and Drug Design	2007	163
24	Expanding the Number of ‘Druggable’ Targets: Non‐Enzymes and Protein–Protein Interactions	Chemical Biology and Drug Design	2013	161
25	Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine	Chemical Biology and Drug Design	2009	158
26	tRF‐Leu‐CAG promotes cell proliferation and cell cycle in non‐small cell lung cancer	Chemical Biology and Drug Design	2017	148
27	Atomic Interactions and Profile of Small Molecules Disrupting Protein–Protein Interfaces: the TIMBAL Database	Chemical Biology and Drug Design	2009	144
28	Insight into Amyloid Structure Using Chemical Probes	Chemical Biology and Drug Design	2011	139
29	Stability of Gold Nanoparticle-Bound DNA toward Biological, Physical, and Chemical Agents	Chemical Biology and Drug Design	2006	138
30	Triazole: A Promising Antitubercular Agent	Chemical Biology and Drug Design	2015	138
31	Carbonic Anhydrase Inhibitors: Inhibition of Human Erythrocyte Isozymes I and II with a Series of Phenolic Acids	Chemical Biology and Drug Design	2010	134
32	Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L	Chemical Biology and Drug Design	2012	132
33	A Chemical Genetic Screen for Cell Cycle Inhibitors in Zebrafish Embryos	Chemical Biology and Drug Design	2006	127
34	Crizotinib‐Resistant Mutants of EML4‐ALK Identified Through an Accelerated Mutagenesis Screen	Chemical Biology and Drug Design	2011	127
35	The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential	Chemical Biology and Drug Design	2009	125
36	Structure‐based Drug Metabolism Predictions for Drug Design	Chemical Biology and Drug Design	2010	124
37	A Thermodynamic Approach to the Affinity Optimization of Drug Candidates	Chemical Biology and Drug Design	2009	122
38	Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy	Chemical Biology and Drug Design	2016	120
39	Novel PPAR‐gamma Agonists Identified from a Natural Product Library: A Virtual Screening, Induced‐Fit Docking and Biological Assay Study	Chemical Biology and Drug Design	2008	117
40	Inhibitors of Apoptotic Proteins: New Targets for Anticancer Therapy	Chemical Biology and Drug Design	2013	117
41	Design features for optimization of tetrapyrrole macrocycles as antimicrobial and anticancer photosensitizers	Chemical Biology and Drug Design	2017	117
42	Overcoming Roadblocks in Lead Optimization: A Thermodynamic Perspective	Chemical Biology and Drug Design	2006	116
43	Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes	Chemical Biology and Drug Design	2018	116
44	Comparison of Biophysical and Biologic Properties of alpha-Helical Enantiomeric Antimicrobial Peptides	Chemical Biology and Drug Design	2006	113
45	Cell‐penetrating Peptides as a Novel Transdermal Drug Delivery System	Chemical Biology and Drug Design	2012	112
46	Searching for New Antimalarial Therapeutics amongst Known Drugs	Chemical Biology and Drug Design	2006	110
47	Synthesis and Anticonvulsant Activity of 6‐Alkoxy‐[1,2,4]Triazolo[3,4‐a]Phthalazines	Chemical Biology and Drug Design	2009	110
48	Antimicrobial β-Peptides and α-Peptoids	Chemical Biology and Drug Design	2011	110
49	New Force Field on Modeling Intrinsically Disordered Proteins	Chemical Biology and Drug Design	2014	110
50	Antimalarial Activity of Newly Synthesized Chalcone Derivatives In Vitro	Chemical Biology and Drug Design	2012	109

Scientometrics

Overviews

Citing Bodies

Chemical Biology and Drug Design

Top Articles