# | Title | Journal | Year | Citations |
---|
1 | RNA-Seq: a revolutionary tool for transcriptomics | Nature Reviews Genetics | 2009 | 10,529 |
2 | Network biology: understanding the cell's functional organization | Nature Reviews Genetics | 2004 | 6,726 |
3 | MicroRNAs: small RNAs with a big role in gene regulation | Nature Reviews Genetics | 2004 | 6,186 |
4 | Sequencing technologies — the next generation | Nature Reviews Genetics | 2010 | 5,942 |
5 | Long non-coding RNAs: insights into functions | Nature Reviews Genetics | 2009 | 5,105 |
6 | The fundamental role of epigenetic events in cancer | Nature Reviews Genetics | 2002 | 4,872 |
7 | Functions of DNA methylation: islands, start sites, gene bodies and beyond | Nature Reviews Genetics | 2012 | 4,840 |
8 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Nature Reviews Genetics | 2008 | 4,577 |
9 | Non-coding RNAs in human disease | Nature Reviews Genetics | 2011 | 4,159 |
10 | The widespread regulation of microRNA biogenesis, function and decay | Nature Reviews Genetics | 2010 | 4,038 |
11 | Network medicine: a network-based approach to human disease | Nature Reviews Genetics | 2011 | 3,987 |
12 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses | Nature Reviews Genetics | 2012 | 3,228 |
13 | Establishing, maintaining and modifying DNA methylation patterns in plants and animals | Nature Reviews Genetics | 2010 | 3,201 |
14 | Coming of age: ten years of next-generation sequencing technologies | Nature Reviews Genetics | 2016 | 3,160 |
15 | Unique features of long non-coding RNA biogenesis and function | Nature Reviews Genetics | 2016 | 2,891 |
16 | The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism | Nature Reviews Genetics | 2006 | 2,833 |
17 | The biogenesis, biology and characterization of circular RNAs | Nature Reviews Genetics | 2019 | 2,832 |
18 | The human microbiome: at the interface of health and disease | Nature Reviews Genetics | 2012 | 2,798 |
19 | Causes and consequences of microRNA dysregulation in cancer | Nature Reviews Genetics | 2009 | 2,791 |
20 | Plant immunity: towards an integrated view of plant–pathogen interactions | Nature Reviews Genetics | 2010 | 2,790 |
21 | Network motifs: theory and experimental approaches | Nature Reviews Genetics | 2007 | 2,789 |
22 | Genome-wide association studies for common diseases and complex traits | Nature Reviews Genetics | 2005 | 2,717 |
23 | DNA methylation landscapes: provocative insights from epigenomics | Nature Reviews Genetics | 2008 | 2,619 |
24 | Long non-coding RNAs: new players in cell differentiation and development | Nature Reviews Genetics | 2014 | 2,616 |
25 | Non-viral vectors for gene-based therapy | Nature Reviews Genetics | 2014 | 2,572 |
26 | DNA methylation: roles in mammalian development | Nature Reviews Genetics | 2013 | 2,541 |
27 | Genome-wide association studies for complex traits: consensus, uncertainty and challenges | Nature Reviews Genetics | 2008 | 2,496 |
28 | DNA methylation and human disease | Nature Reviews Genetics | 2005 | 2,449 |
29 | A unified classification system for eukaryotic transposable elements | Nature Reviews Genetics | 2007 | 2,396 |
30 | Progress and problems with the use of viral vectors for gene therapy | Nature Reviews Genetics | 2003 | 2,213 |
31 | Genome-wide genetic marker discovery and genotyping using next-generation sequencing | Nature Reviews Genetics | 2011 | 2,198 |
32 | Environmental epigenomics and disease susceptibility | Nature Reviews Genetics | 2007 | 2,180 |
33 | The many roles of histone deacetylases in development and physiology: implications for disease and therapy | Nature Reviews Genetics | 2009 | 2,173 |
34 | Small silencing RNAs: an expanding universe | Nature Reviews Genetics | 2009 | 2,142 |
35 | Genomic imprinting: parental influence on the genome | Nature Reviews Genetics | 2001 | 2,120 |
36 | To err (meiotically) is human: the genesis of human aneuploidy | Nature Reviews Genetics | 2001 | 2,118 |
37 | Stochasticity in gene expression: from theories to phenotypes | Nature Reviews Genetics | 2005 | 2,066 |
38 | Chromosome territories, nuclear architecture and gene regulation in mammalian cells | Nature Reviews Genetics | 2001 | 2,056 |
39 | Gene silencing by microRNAs: contributions of translational repression and mRNA decay | Nature Reviews Genetics | 2011 | 2,009 |
40 | The advantages and disadvantages of being polyploid | Nature Reviews Genetics | 2005 | 1,950 |
41 | The molecular hallmarks of epigenetic control | Nature Reviews Genetics | 2016 | 1,945 |
42 | Linking DNA methylation and histone modification: patterns and paradigms | Nature Reviews Genetics | 2009 | 1,944 |
43 | Biological robustness | Nature Reviews Genetics | 2004 | 1,937 |
44 | Listening to silence and understanding nonsense: exonic mutations that affect splicing | Nature Reviews Genetics | 2002 | 1,923 |
45 | Cancer epigenomics: DNA methylomes and histone-modification maps | Nature Reviews Genetics | 2007 | 1,916 |
46 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes | Nature Reviews Genetics | 2000 | 1,878 |
47 | Genome editing with engineered zinc finger nucleases | Nature Reviews Genetics | 2010 | 1,863 |
48 | Microsatellites: simple sequences with complex evolution | Nature Reviews Genetics | 2004 | 1,854 |
49 | Animal models of human disease: zebrafish swim into view | Nature Reviews Genetics | 2007 | 1,829 |
50 | RNA sequencing: advances, challenges and opportunities | Nature Reviews Genetics | 2011 | 1,770 |