# | Title | Journal | Year | Citations |
---|
|
1 | RNA-Seq: a revolutionary tool for transcriptomics | Nature Reviews Genetics | 2009 | 10,838 |
2 | Network biology: understanding the cell's functional organization | Nature Reviews Genetics | 2004 | 6,830 |
3 | MicroRNAs: small RNAs with a big role in gene regulation | Nature Reviews Genetics | 2004 | 6,279 |
4 | Sequencing technologies — the next generation | Nature Reviews Genetics | 2010 | 6,060 |
5 | Long non-coding RNAs: insights into functions | Nature Reviews Genetics | 2009 | 5,206 |
6 | Functions of DNA methylation: islands, start sites, gene bodies and beyond | Nature Reviews Genetics | 2012 | 5,014 |
7 | The fundamental role of epigenetic events in cancer | Nature Reviews Genetics | 2002 | 4,929 |
8 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Nature Reviews Genetics | 2008 | 4,655 |
9 | Non-coding RNAs in human disease | Nature Reviews Genetics | 2011 | 4,269 |
10 | The widespread regulation of microRNA biogenesis, function and decay | Nature Reviews Genetics | 2010 | 4,138 |
11 | Network medicine: a network-based approach to human disease | Nature Reviews Genetics | 2011 | 4,108 |
12 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses | Nature Reviews Genetics | 2012 | 3,343 |
13 | Coming of age: ten years of next-generation sequencing technologies | Nature Reviews Genetics | 2016 | 3,335 |
14 | Establishing, maintaining and modifying DNA methylation patterns in plants and animals | Nature Reviews Genetics | 2010 | 3,308 |
15 | The biogenesis, biology and characterization of circular RNAs | Nature Reviews Genetics | 2019 | 3,094 |
16 | Unique features of long non-coding RNA biogenesis and function | Nature Reviews Genetics | 2016 | 3,031 |
17 | The human microbiome: at the interface of health and disease | Nature Reviews Genetics | 2012 | 2,903 |
18 | The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism | Nature Reviews Genetics | 2006 | 2,899 |
19 | Plant immunity: towards an integrated view of plant–pathogen interactions | Nature Reviews Genetics | 2010 | 2,889 |
20 | Network motifs: theory and experimental approaches | Nature Reviews Genetics | 2007 | 2,847 |
21 | Causes and consequences of microRNA dysregulation in cancer | Nature Reviews Genetics | 2009 | 2,827 |
22 | Genome-wide association studies for common diseases and complex traits | Nature Reviews Genetics | 2005 | 2,745 |
23 | Long non-coding RNAs: new players in cell differentiation and development | Nature Reviews Genetics | 2014 | 2,677 |
24 | DNA methylation landscapes: provocative insights from epigenomics | Nature Reviews Genetics | 2008 | 2,668 |
25 | Non-viral vectors for gene-based therapy | Nature Reviews Genetics | 2014 | 2,659 |
26 | DNA methylation: roles in mammalian development | Nature Reviews Genetics | 2013 | 2,608 |
27 | Genome-wide association studies for complex traits: consensus, uncertainty and challenges | Nature Reviews Genetics | 2008 | 2,523 |
28 | DNA methylation and human disease | Nature Reviews Genetics | 2005 | 2,511 |
29 | A unified classification system for eukaryotic transposable elements | Nature Reviews Genetics | 2007 | 2,494 |
30 | Progress and problems with the use of viral vectors for gene therapy | Nature Reviews Genetics | 2003 | 2,260 |
31 | Genome-wide genetic marker discovery and genotyping using next-generation sequencing | Nature Reviews Genetics | 2011 | 2,244 |
32 | The many roles of histone deacetylases in development and physiology: implications for disease and therapy | Nature Reviews Genetics | 2009 | 2,217 |
33 | Environmental epigenomics and disease susceptibility | Nature Reviews Genetics | 2007 | 2,212 |
34 | Small silencing RNAs: an expanding universe | Nature Reviews Genetics | 2009 | 2,168 |
35 | To err (meiotically) is human: the genesis of human aneuploidy | Nature Reviews Genetics | 2001 | 2,163 |
36 | Genomic imprinting: parental influence on the genome | Nature Reviews Genetics | 2001 | 2,132 |
37 | Chromosome territories, nuclear architecture and gene regulation in mammalian cells | Nature Reviews Genetics | 2001 | 2,103 |
38 | Stochasticity in gene expression: from theories to phenotypes | Nature Reviews Genetics | 2005 | 2,103 |
39 | The molecular hallmarks of epigenetic control | Nature Reviews Genetics | 2016 | 2,076 |
40 | Gene silencing by microRNAs: contributions of translational repression and mRNA decay | Nature Reviews Genetics | 2011 | 2,054 |
41 | The advantages and disadvantages of being polyploid | Nature Reviews Genetics | 2005 | 2,021 |
42 | Linking DNA methylation and histone modification: patterns and paradigms | Nature Reviews Genetics | 2009 | 1,983 |
43 | Biological robustness | Nature Reviews Genetics | 2004 | 1,975 |
44 | DNA methylation-based biomarkers and the epigenetic clock theory of ageing | Nature Reviews Genetics | 2018 | 1,955 |
45 | Cancer epigenomics: DNA methylomes and histone-modification maps | Nature Reviews Genetics | 2007 | 1,945 |
46 | Listening to silence and understanding nonsense: exonic mutations that affect splicing | Nature Reviews Genetics | 2002 | 1,936 |
47 | Genome editing with engineered zinc finger nucleases | Nature Reviews Genetics | 2010 | 1,915 |
48 | Transcriptional architecture of the mammalian circadian clock | Nature Reviews Genetics | 2017 | 1,911 |
49 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes | Nature Reviews Genetics | 2000 | 1,893 |
50 | Microsatellites: simple sequences with complex evolution | Nature Reviews Genetics | 2004 | 1,893 |