| # | Title | Journal | Year | Citations |
|---|
| 1 | Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA | Gene Therapy | 1999 | 1,659 |
| 2 | Plat-E: an efficient and stable system for transient packaging of retroviruses | Gene Therapy | 2000 | 1,536 |
| 3 | Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield | Gene Therapy | 1999 | 1,177 |
| 4 | PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery | Gene Therapy | 1999 | 1,168 |
| 5 | Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial | Gene Therapy | 2000 | 914 |
| 6 | Gene Therapy Progress and Prospects: Nonviral vectors | Gene Therapy | 2002 | 888 |
| 7 | Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo | Gene Therapy | 2002 | 857 |
| 8 | The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes | Gene Therapy | 1997 | 797 |
| 9 | ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties | Gene Therapy | 2003 | 667 |
| 10 | RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo | Gene Therapy | 2005 | 660 |
| 11 | Immune responses to adenovirus and adeno-associated virus in humans | Gene Therapy | 1999 | 655 |
| 12 | Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis | Gene Therapy | 2001 | 627 |
| 13 | Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer | Gene Therapy | 1999 | 576 |
| 14 | Versatile retroviral vectors for potential use in gene therapy | Gene Therapy | 1994 | 571 |
| 15 | Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma | Gene Therapy | 2000 | 569 |
| 16 | Nonviral gene therapy: promises and challenges | Gene Therapy | 2000 | 565 |
| 17 | The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells | Gene Therapy | 1998 | 562 |
| 18 | Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model | Gene Therapy | 2004 | 554 |
| 19 | Immune responses to gene therapy vectors: influence on vector function and effector mechanisms | Gene Therapy | 2004 | 547 |
| 20 | Progress and prospects: immune responses to viral vectors | Gene Therapy | 2010 | 530 |
| 21 | Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo | Gene Therapy | 2001 | 523 |
| 22 | Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery | Gene Therapy | 2004 | 520 |
| 23 | Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery | Gene Therapy | 2006 | 520 |
| 24 | Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells | Gene Therapy | 2008 | 510 |
| 25 | On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids | Gene Therapy | 2001 | 508 |
| 26 | Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo | Gene Therapy | 2003 | 491 |
| 27 | Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus | Gene Therapy | 2000 | 489 |
| 28 | Cationic liposome-mediated gene transfer | Gene Therapy | 1995 | 477 |
| 29 | Adeno-associated virus vectors can be efficiently produced without helper virus | Gene Therapy | 1998 | 467 |
| 30 | In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes | Gene Therapy | 1997 | 464 |
| 31 | Protamine sulfate enhances lipid-mediated gene transfer | Gene Therapy | 1997 | 439 |
| 32 | Progress and prospects: naked DNA gene transfer and therapy | Gene Therapy | 2003 | 404 |
| 33 | Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle | Gene Therapy | 2002 | 396 |
| 34 | Molecular basis of the inflammatory response to adenovirus vectors | Gene Therapy | 2003 | 395 |
| 35 | Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo | Gene Therapy | 2003 | 380 |
| 36 | Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery | Gene Therapy | 1999 | 377 |
| 37 | Characterization of cationic lipid-protamine–DNA (LPD) complexes for intravenous gene delivery | Gene Therapy | 1998 | 375 |
| 38 | Polyethylenimine-based intravenous delivery of transgenes to mouse lung | Gene Therapy | 1998 | 375 |
| 39 | Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid | Gene Therapy | 2007 | 375 |
| 40 | Gene therapy progress and prospects: non-viral gene therapy by systemic delivery | Gene Therapy | 2006 | 374 |
| 41 | MicroRNA therapeutics | Gene Therapy | 2011 | 369 |
| 42 | Gene therapy progress and prospects: Ultrasound for gene transfer | Gene Therapy | 2007 | 365 |
| 43 | Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers | Gene Therapy | 2004 | 363 |
| 44 | Chemical modification and design of anti-miRNA oligonucleotides | Gene Therapy | 2011 | 363 |
| 45 | Electropermeabilization of skeletal muscle enhances gene transfer in vivo | Gene Therapy | 1999 | 361 |
| 46 | Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? | Gene Therapy | 2006 | 361 |
| 47 | Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery | Gene Therapy | 1997 | 358 |
| 48 | Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection | Gene Therapy | 1999 | 356 |
| 49 | Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals | Gene Therapy | 1999 | 356 |
| 50 | Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents | Gene Therapy | 2000 | 351 |
