| 1 | Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAHs) | Regulatory Toxicology and Pharmacology | 1992 | 2,298 |
| 2 | Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products | Regulatory Toxicology and Pharmacology | 2015 | 1,812 |
| 3 | Novel database for exposure to fragrance ingredients in cosmetics and personal care products | Regulatory Toxicology and Pharmacology | 2015 | 1,756 |
| 4 | Application of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products | Regulatory Toxicology and Pharmacology | 2017 | 1,747 |
| 5 | Integrating habits and practices data for soaps, cosmetics and air care products into an existing aggregate exposure model | Regulatory Toxicology and Pharmacology | 2017 | 1,724 |
| 6 | Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern | Regulatory Toxicology and Pharmacology | 2012 | 1,549 |
| 7 | A strategy for structuring and reporting a read-across prediction of toxicity | Regulatory Toxicology and Pharmacology | 2015 | 1,461 |
| 8 | Concordance of the Toxicity of Pharmaceuticals in Humans and in Animals | Regulatory Toxicology and Pharmacology | 2000 | 1,214 |
| 9 | A Systematic Approach for Evaluating the Quality of Experimental Toxicological and Ecotoxicological Data | Regulatory Toxicology and Pharmacology | 1997 | 774 |
| 10 | Trace element risk assessment: essentiality vs. toxicity | Regulatory Toxicology and Pharmacology | 2003 | 583 |
| 11 | Safety Evaluation and Risk Assessment of the Herbicide Roundup and Its Active Ingredient, Glyphosate, for Humans | Regulatory Toxicology and Pharmacology | 2000 | 571 |
| 12 | Risk assessment of the mycotoxin zearalenone | Regulatory Toxicology and Pharmacology | 1987 | 555 |
| 13 | Comparison of Cramer classification between Toxtree, the OECD QSAR Toolbox and expert judgment | Regulatory Toxicology and Pharmacology | 2015 | 544 |
| 14 | The Dermal Sensitisation Threshold—A TTC approach for allergic contact dermatitis | Regulatory Toxicology and Pharmacology | 2008 | 434 |
| 15 | Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive | Regulatory Toxicology and Pharmacology | 2015 | 426 |
| 16 | Oral toxicity of silver ions, silver nanoparticles and colloidal silver – A review | Regulatory Toxicology and Pharmacology | 2014 | 418 |
| 17 | Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains | Regulatory Toxicology and Pharmacology | 2011 | 413 |
| 18 | Reference dose (RfD): Description and use in health risk assessments | Regulatory Toxicology and Pharmacology | 1988 | 400 |
| 19 | The safety of chitosan as a pharmaceutical excipient | Regulatory Toxicology and Pharmacology | 2010 | 400 |
| 20 | Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied | Regulatory Toxicology and Pharmacology | 2015 | 394 |
| 21 | Health safety issues of synthetic food colorants | Regulatory Toxicology and Pharmacology | 2015 | 384 |
| 22 | Review of health safety aspects of nanotechnologies in food production | Regulatory Toxicology and Pharmacology | 2009 | 367 |
| 23 | Occurrences, Uses, and Properties of Chromium | Regulatory Toxicology and Pharmacology | 1997 | 357 |
| 24 | Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin | Regulatory Toxicology and Pharmacology | 2006 | 344 |
| 25 | Arsenic exposure: A public health problem leading to several cancers | Regulatory Toxicology and Pharmacology | 2020 | 344 |
| 26 | Health Implications of Nitrate and Nitrite in Drinking Water: An Update on Methemoglobinemia Occurrence and Reproductive and Developmental Toxicity | Regulatory Toxicology and Pharmacology | 1996 | 341 |
| 27 | Potency Equivalency Factors for Some Polycyclic Aromatic Hydrocarbons and Polycyclic Aromatic Hydrocarbon Derivatives | Regulatory Toxicology and Pharmacology | 1998 | 333 |
| 28 | Health benefits and potential risks related to consumption of fish or fish oil | Regulatory Toxicology and Pharmacology | 2003 | 333 |
| 29 | Chromium as an Essential Nutrient for Humans | Regulatory Toxicology and Pharmacology | 1997 | 330 |
| 30 | Ranking and prioritization of environmental risks of pharmaceuticals in surface waters | Regulatory Toxicology and Pharmacology | 2004 | 324 |
| 31 | Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs | Regulatory Toxicology and Pharmacology | 2011 | 312 |
| 32 | Assessing skin sensitization hazard in mice and men using non-animal test methods | Regulatory Toxicology and Pharmacology | 2015 | 311 |
| 33 | Human pharmaceuticals in US surface waters: A human health risk assessment | Regulatory Toxicology and Pharmacology | 2005 | 310 |
| 34 | A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity | Regulatory Toxicology and Pharmacology | 2006 | 310 |
| 35 | Potential adverse effects of phthalic acid esters on human health: A review of recent studies on reproduction | Regulatory Toxicology and Pharmacology | 2008 | 305 |
| 36 | The hormesis database: The occurrence of hormetic dose responses in the toxicological literature | Regulatory Toxicology and Pharmacology | 2011 | 304 |
| 37 | Consumer Exposure to Fragrance Ingredients: Providing Estimates for Safety Evaluation | Regulatory Toxicology and Pharmacology | 2002 | 295 |
| 38 | Bacteriophage P100 for control of Listeria monocytogenes in foods: Genome sequence, bioinformatic analyses, oral toxicity study, and application | Regulatory Toxicology and Pharmacology | 2005 | 295 |
| 39 | The safety of green tea and green tea extract consumption in adults – Results of a systematic review | Regulatory Toxicology and Pharmacology | 2018 | 291 |
| 40 | Criteria for Development of a Database for Safety Evaluation of Fragrance Ingredients | Regulatory Toxicology and Pharmacology | 2000 | 282 |
| 41 | Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol | Regulatory Toxicology and Pharmacology | 2016 | 278 |
| 42 | Safety and Advantages of Bacillus thuringiensis-Protected Plants to Control Insect Pests | Regulatory Toxicology and Pharmacology | 2000 | 277 |
| 43 | Regulatory history and experimental support of uncertainty (safety) factors | Regulatory Toxicology and Pharmacology | 1983 | 269 |
| 44 | A Cancer Risk Assessment of Di(2-ethylhexyl)phthalate: Application of the New U.S. EPA Risk Assessment Guidelines | Regulatory Toxicology and Pharmacology | 1999 | 257 |
| 45 | What do we (need to) know about the kinetic properties of nanoparticles in the body? | Regulatory Toxicology and Pharmacology | 2007 | 251 |
| 46 | IPCS Conceptual Framework for Evaluating a Mode of Action for Chemical Carcinogenesis | Regulatory Toxicology and Pharmacology | 2001 | 249 |
| 47 | Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions | Regulatory Toxicology and Pharmacology | 2005 | 247 |
| 48 | Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review | Regulatory Toxicology and Pharmacology | 2018 | 246 |
| 49 | Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA) | Regulatory Toxicology and Pharmacology | 2014 | 245 |
| 50 | Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects | Regulatory Toxicology and Pharmacology | 2012 | 244 |