About
Technology
Issues
FAQ
Title
Abstract
Text
Figure Captions
Table Cells
Section Titles
Keywords
Subjects
Authors
From
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1995
1990
1985
1980
1975
1970
1960
1950
1940
1930
1920
1910
1900
1850
1800
1700
1600
To
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1995
1990
1985
1980
1975
1970
1960
1950
1940
1930
1920
1910
1900
1850
1800
1700
1600
All Types
Articles
Communications
Reviews
Discussions
Case Reports
Chapters
Books
News
Editorials
Order By
Order By Year ASC
Order By Year DESC
Order By Citations ASC
Order By Citations DESC
Go
Scientometrics
Impact Factor
Discipline Ranks
H-Index
G-Index
Articles
Citations
Article Citations
Citation Distribution
Search This Journal
Overviews
Top Institutions
Top Schools
Top Authors
Prolific Authors
Top Articles
exaly
›
Journals
›
Drug Metabolism and Disposition
›
Top Articles
Drug Metabolism and Disposition
Pharmacology
4
(top 4%)
Impact Factor
4.3
(top 4%)
extended IF
176
(top 1%)
H-Index
1.7K
authors
8.9K
papers
292.5K
citations
5.6K
citing journals
58.5K
citing authors
Most Cited Articles of Drug Metabolism and Disposition
Title
Year
Citations
High absorption but very low bioavailability of oral resveratrol in humans
2004
1.3K
Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene
1974
976
Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes
1999
825
Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios
2004
771
Acetaminophen-induced hepatotoxicity
2003
739
The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective
2003
667
The human intestinal cytochrome P450 "pie"
2006
666
Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
2010
600
Biotransformation of curcumin through reduction and glucuronidation in mice
1999
596
Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties
2003
592
The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
2008
545
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells
2006
501
Apixaban metabolism and pharmacokinetics after oral administration to humans
2009
479
Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities
2004
461
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
2007
445
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
1999
445
Validated assays for human cytochrome P450 activities
2004
438
The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model
2005
408
Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities
1991
399
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes
2002
376
Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions
2007
375
Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes
1995
372
Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7
2002
371
In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system
2008
367
Structure and stereochemistry of the active metabolite of clopidogrel
2002
366
0
1
2
next
How are inpact factors calculated?
The impact factor (IF) is calculated by counting citations from peer-reviewed journals only.
extended IF
also counts citations from books and conference papers. However, no patent, abstract, working papers, online documents, etc., are covered.
site/software ©
exaly
; All materials licenced under
CC by-SA
.