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Top Articles

#TitleJournalYearCitations
1Toll-like receptors in innate immunityInternational Immunology20042,786
2Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.International Immunology19981,364
3The roles of TLRs, RLRs and NLRs in pathogen recognitionInternational Immunology20091,355
4Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytesInternational Immunology19961,316
5Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathwayInternational Immunology20001,201
6Exosomal-like vesicles are present in human blood plasmaInternational Immunology20051,126
7Discrimination of bacterial lipoproteins by Toll-like receptor 6International Immunology20011,112
8PD-1 and PD-1 ligands: from discovery to clinical applicationInternational Immunology20071,064
9Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid miceInternational Immunology1993988
10Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine productionInternational Immunology2007756
11Regulatory T cells: how do they suppress immune responses?International Immunology2009735
12Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga miceInternational Immunology1997726
13Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cellsInternational Immunology2004713
14Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokineInternational Immunology1999665
15IL-6: from its discovery to clinical applicationsInternational Immunology2010664
16IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK CellsInternational Immunology2008550
17Inducible gene knockout of transcription factor recombination signal binding protein‐J reveals its essential role in T versus B lineage decisionInternational Immunology2002533
18IL-6 in inflammation, autoimmunity and cancerInternational Immunology2021500
19Anti-TNF therapy: past, present and futureInternational Immunology2015455
20Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune systemInternational Immunology2008451
21Activation interferes with the APO-1 pathway in mature human T cellsInternational Immunology1993444
22Differences in promiscuity for antibody–FcRn interactions across species: implications for therapeutic antibodiesInternational Immunology2001430
23Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responsesInternational Immunology1998425
24Human Fas ligand: gene structure, chromosomal location and species specificityInternational Immunology1994424
25PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cellsInternational Immunology2004413
26Roles of regulatory T cells in cancer immunityInternational Immunology2016412
27Macrophages in inflammation, repair and regenerationInternational Immunology2018402
28Hyperferritinemia and inflammationInternational Immunology2017385
29Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependencyInternational Immunology1998383
30Targeted disruption of the MHC class II Aa gene in C57BL/6 miceInternational Immunology1993375
31IL-10 selectively induces HLA-G expression in human trophoblasts and monocytesInternational Immunology1999373
32High-level IL-12 production by human dendritic cells requires two signalsInternational Immunology1998370
33Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locusInternational Immunology1993369
34Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivoInternational Immunology1994367
35NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcomaInternational Immunology2001365
36Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10International Immunology1990357
37LacZ inducible, antigen/MHC-specific T cell hybridsInternational Immunology1994353
38IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinasesInternational Immunology1999346
39CD4 + T-cell subsets in inflammatory diseases: beyond the T h 1/T h 2 paradigmInternational Immunology2016343
40Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavityInternational Immunology1989339
41Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokines IL-10 and transforming growth factor-β but not by a Th1 to Th2 shiftInternational Immunology2000334
42Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependentInternational Immunology1993326
43Reversal of in vitro T cell clonal anergy by IL-2 stimulationInternational Immunology1992322
44Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysisInternational Immunology2006320
45Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell deathInternational Immunology1994317
46IL-5- and eosinophil-mediated inflammation: from discovery to therapyInternational Immunology2009315
47CCR4 and its ligands: from bench to bedsideInternational Immunology2015314
48Survival of long-lived plasma cells is independent of antigen [In Process Citation]International Immunology1998307
49IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cellsInternational Immunology2004305
50IL-12 synergizes with IL-18 or IL-1β for IFN-γ production from human T cellsInternational Immunology2000302