# | Title | Journal | Year | Citations |
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1 | Labeled 2-deoxy-D-glucose analogs. 18F-labeled 2-deoxy-2-fluoro-D-glucose, 2-deoxy-2-fluoro-D-mannose and 14C-2-deoxy-2-fluoro-D-glucose | Journal of Labelled Compounds and Radiopharmaceuticals | 1978 | 349 |
2 | Aryltrimethylammonium trifluoromethanesulfonates as precursors to aryl [18F]fluorides: Improved synthesis of [18F]GBR-13119 | Journal of Labelled Compounds and Radiopharmaceuticals | 1989 | 167 |
3 | Synthesis of N-(11C) methyl, N-(methyl-1 propyl), (chloro-2 phenyl)-1 isoquinoleine carboxamide-3 (PK 11195): A new ligand for peripheral benzodiazepine receptors | Journal of Labelled Compounds and Radiopharmaceuticals | 1984 | 149 |
4 | Pd‐ and Pt‐catalyzed H/D exchange methods and their application for internal MS standard preparation from a Sanofi‐Aventis perspective | Journal of Labelled Compounds and Radiopharmaceuticals | 2010 | 133 |
5 | Deuteration of acetanilides and other substituted aromatics using [Ir(COD)(Cy3P)(Py)]PF6 as catalyst | Journal of Labelled Compounds and Radiopharmaceuticals | 1995 | 132 |
6 | Remotely-controlled production of the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635, via 11C-carboxylation of an immobilized Grignard reagent | Journal of Labelled Compounds and Radiopharmaceuticals | 1996 | 117 |
7 | The development and use of novel iridium complexes as catalysts for ortho‐directed hydrogen isotope exchange reactions | Journal of Labelled Compounds and Radiopharmaceuticals | 2010 | 107 |
8 | Precursor synthesis and radiolabelling of the dopamine D2 receptor ligand [11C]raclopride from [11C]methyl triflate | Journal of Labelled Compounds and Radiopharmaceuticals | 1999 | 105 |
9 | [11C]Carbon monoxide, a versatile and useful precursor in labelling chemistry for PET‐ligand development | Journal of Labelled Compounds and Radiopharmaceuticals | 2007 | 104 |
10 | Tritium: a coming of age for drug discovery and development ADME studies | Journal of Labelled Compounds and Radiopharmaceuticals | 2012 | 103 |
11 | Preparation of N.C.A. [17-18F]-fluoroheptadecanoic acid in high yields via aminopolyether supported, nucleophilic fluorination | Journal of Labelled Compounds and Radiopharmaceuticals | 1986 | 101 |
12 | Technetium‐99m radiochemistry for pharmaceutical applications | Journal of Labelled Compounds and Radiopharmaceuticals | 2017 | 101 |
13 | [11C]Methylation on a C18 Sep-Pak cartridge: a convenient way to produce [N-methyl-11C]choline | Journal of Labelled Compounds and Radiopharmaceuticals | 2000 | 92 |
14 | ‘Click labelling’ in PET radiochemistry | Journal of Labelled Compounds and Radiopharmaceuticals | 2009 | 90 |
15 | Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals | Journal of Labelled Compounds and Radiopharmaceuticals | 2014 | 90 |
16 | A rapid one-step radiosynthesis of theβ-amyloid imaging radiotracerN-methyl-[11C]2-(4′-methylaminophenyl)-6-hydroxybenzothiazole([11C]-6-OH-BTA-1) | Journal of Labelled Compounds and Radiopharmaceuticals | 2004 | 88 |
17 | Metal‐catalysed isotopic exchange labelling: 30 years of experience in pharmaceutical R&D | Journal of Labelled Compounds and Radiopharmaceuticals | 2010 | 86 |
18 | Synthesis of [methoxy-3H]- and [methoxy-11C]- labelled raclopride. Specific dopamine-D2 receptor ligands | Journal of Labelled Compounds and Radiopharmaceuticals | 1987 | 82 |
19 | Solid phase extraction—an alternative to the use of rotary evaporators for solvent removal in the rapid formulation of PET radiopharmaceuticals | Journal of Labelled Compounds and Radiopharmaceuticals | 1999 | 82 |
20 | The N.C.A. nucleophilic 18F-fluorination of 1,N-disubstituted alkanes as fluoroalkylation agents | Journal of Labelled Compounds and Radiopharmaceuticals | 1987 | 80 |
21 | Radiosynthesis of [18F]DPA‐714, a selective radioligand for imaging the translocator protein (18 kDa) with PET | Journal of Labelled Compounds and Radiopharmaceuticals | 2008 | 76 |
22 | Highlighting the versatility of the tracerlab synthesis modules. Part 1: fully automated production of [18F]labelled radiopharmaceuticals using a Tracerlab FXFN | Journal of Labelled Compounds and Radiopharmaceuticals | 2011 | 76 |
23 | RGD‐based PET tracers for imaging receptor integrin αvβ3 expression | Journal of Labelled Compounds and Radiopharmaceuticals | 2013 | 76 |
24 | 2-[18F]fluoropyridines by no-carrier-added nucleophilic aromatic substitution with [18F]FK-K222—a comparative study | Journal of Labelled Compounds and Radiopharmaceuticals | 1999 | 75 |
25 | Isotopic fractionation of organic compounds in chromatography | Journal of Labelled Compounds and Radiopharmaceuticals | 1999 | 73 |
26 | Synthesis of [18F]-labeled 2?-deoxy-2?-fluoro-5-methyl-1-?-D-arabinofuranosyluracil ([18F]-FMAU) | Journal of Labelled Compounds and Radiopharmaceuticals | 2002 | 73 |
27 | Organoiridium complexes for hydrogen isotope exchange labeling | Journal of Labelled Compounds and Radiopharmaceuticals | 2007 | 73 |
28 | Multifunctional targeted therapy system based on 99mTc/177Lu‐labeled gold nanoparticles‐Tat(49–57)‐Lys3‐bombesin internalized in nuclei of prostate cancer cells | Journal of Labelled Compounds and Radiopharmaceuticals | 2013 | 73 |
29 | Tc-99m-markierung von cymantren-analogen verbindungen mit verschiedenen substituenten - ein neuer zugang zu Tc-99m radiodiagnostika | Journal of Labelled Compounds and Radiopharmaceuticals | 1992 | 72 |
30 | A concise radiosynthesis of the tau radiopharmaceutical, [18F]T807 | Journal of Labelled Compounds and Radiopharmaceuticals | 2013 | 70 |
31 | Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [11C]A‐740003 as a novel tracer of neuroinflammation | Journal of Labelled Compounds and Radiopharmaceuticals | 2014 | 70 |
32 | Re‐thinking the role of radiometal isotopes: Towards a future concept for theranostic radiopharmaceuticals | Journal of Labelled Compounds and Radiopharmaceuticals | 2018 | 70 |
33 | Transition metal mediated synthesis using [11C]CO at low pressure – a simplified method for 11C‐carbonylation | Journal of Labelled Compounds and Radiopharmaceuticals | 2012 | 69 |
34 | Labeled aryl fluorides from the nucleophilic displacement of activated nitro groups by 18F-F− | Journal of Labelled Compounds and Radiopharmaceuticals | 1983 | 68 |
35 | Synthesis of a radiotracer for studying nicotinic acetylcholine receptors: (+/−)-exo-2-(2-[18F]fluoro-5-pyridyl)-7-azabicyclo[2.2.1]heptane | Journal of Labelled Compounds and Radiopharmaceuticals | 1996 | 67 |
36 | Fluoroazomycin arabinoside (FAZA): synthesis,2H and3H-labelling and preliminary biological evaluation of a novel 2-nitroimidazole marker of tissue hypoxia | Journal of Labelled Compounds and Radiopharmaceuticals | 1999 | 67 |
37 | Metal‐catalysed hydrogen isotope exchange labelling: a brief overview | Journal of Labelled Compounds and Radiopharmaceuticals | 2010 | 67 |
38 | Radiosynthesis of [11C]SL25.1188 via [11C]CO2 fixation for imaging monoamine oxidase B | Journal of Labelled Compounds and Radiopharmaceuticals | 2011 | 67 |
39 | Facile synthesis of N‐succinimidyl 4‐[18F]fluorobenzoate ([18F]SFB) for protein labeling | Journal of Labelled Compounds and Radiopharmaceuticals | 2008 | 66 |
40 | Transition metal mediated [11C]carbonylation reactions: recent advances and applications | Journal of Labelled Compounds and Radiopharmaceuticals | 2014 | 66 |
41 | Synthesis of 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine, a highly potent radioligand for in vivo imaging central nicotinic acetylcholine receptors | Journal of Labelled Compounds and Radiopharmaceuticals | 1998 | 65 |
42 | Radiosynthesis of carbon-11 labelled N-methyl-2-(arylthio)benzylamines: potential radiotracers for the serotonin reuptake receptor | Journal of Labelled Compounds and Radiopharmaceuticals | 1999 | 65 |
43 | A general method for labeling oligodeoxynucleotides with 18F for in vivo PET imaging | Journal of Labelled Compounds and Radiopharmaceuticals | 1997 | 64 |
44 | 14Carbon monoxide made simple – novel approach to the generation, utilization, and scrubbing of 14carbon monoxide | Journal of Labelled Compounds and Radiopharmaceuticals | 2012 | 64 |
45 | N.C.A. [18F]-labelling of aliphatic compounds in high yields via aminopolyether - supported nucleophilic substitution | Journal of Labelled Compounds and Radiopharmaceuticals | 1986 | 63 |
46 | The development and use of iridium(I) phosphine systems for ortho‐directed hydrogen‐isotope exchange | Journal of Labelled Compounds and Radiopharmaceuticals | 2010 | 63 |
47 | 6-[18F]Fluoro-L-DOPA by radiofluorodestannylation: a short and simple synthesis of a new labelling precursor | Journal of Labelled Compounds and Radiopharmaceuticals | 1998 | 62 |
48 | Automated PET radiosyntheses using microfluidic devices | Journal of Labelled Compounds and Radiopharmaceuticals | 2007 | 62 |
49 | Carbon-11 labelling of MADAM in two different positions: a highly selective PET radioligand for the serotonin transporter | Journal of Labelled Compounds and Radiopharmaceuticals | 2001 | 61 |
50 | Fast [18F]FDG synthesis by alkaline hydrolysis on a low polarity solid phase support | Journal of Labelled Compounds and Radiopharmaceuticals | 2002 | 61 |