| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery disease | European Journal of Clinical Investigation | 2009 | 1,336 |
| 2 | Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction | European Journal of Clinical Investigation | 2002 | 1,073 |
| 3 | A catalogue of reporting guidelines for health research | European Journal of Clinical Investigation | 2010 | 967 |
| 4 | A Taql polymorphism in the human interleukin‐1β (IL‐1β) gene correlates with IL‐1β secretion in vitro | European Journal of Clinical Investigation | 1992 | 895 |
| 5 | SARS‐coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS | European Journal of Clinical Investigation | 2009 | 754 |
| 6 | Fabry disease defined: baseline clinical manifestations of 366 patients in the Fabry Outcome Survey | European Journal of Clinical Investigation | 2004 | 716 |
| 7 | Very high prevalence of thyroid nodules detected by high frequency (13 MHz) ultrasound examination | European Journal of Clinical Investigation | 2009 | 710 |
| 8 | Standards and standardization in mastocytosis: Consensus Statements on Diagnostics, Treatment Recommendations and Response Criteria | European Journal of Clinical Investigation | 2007 | 682 |
| 9 | Endogenous nitric oxide: physiology, pathology and clinical relevance | European Journal of Clinical Investigation | 1991 | 667 |
| 10 | Prevention of early postmenopausal bone loss: controlled 2‐year study in 315 normal females | European Journal of Clinical Investigation | 1980 | 621 |
| 11 | Glucagon‐like peptide‐1 cells in the gastrointestinal tract and pancreas of rat, pig and man | European Journal of Clinical Investigation | 1992 | 561 |
| 12 | Time to challenge the spurious hierarchy of systematic over narrative reviews? | European Journal of Clinical Investigation | 2018 | 474 |
| 13 | The fetal and infant origins of disease | European Journal of Clinical Investigation | 1995 | 443 |
| 14 | Anti‐inflammatory effects of exercise: role in diabetes and cardiovascular disease | European Journal of Clinical Investigation | 2017 | 438 |
| 15 | Adipokine dysregulation and adipose tissue inflammation in human obesity | European Journal of Clinical Investigation | 2018 | 436 |
| 16 | Radioimmunoassay of Prostaglandins Fα, E1 and E2 in Human Plasma | European Journal of Clinical Investigation | 1975 | 421 |
| 17 | Radioimmunoassay for type III procollagen peptide and its application to human liver disease | European Journal of Clinical Investigation | 1979 | 396 |
| 18 | Time‐course and dose‐response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome | European Journal of Clinical Investigation | 1993 | 384 |
| 19 | Comparison of intestinal absorption of cholesterol with different plant sterols in man* | European Journal of Clinical Investigation | 1993 | 371 |
| 20 | Size and strength of the quadriceps muscles of old and young women* | European Journal of Clinical Investigation | 1984 | 357 |
| 21 | Novel insights into glucocorticoid‐mediated diabetogenic effects: towards expansion of therapeutic options? | European Journal of Clinical Investigation | 2009 | 357 |
| 22 | Antioxidant status in patients with uncomplicated insulin‐dependent and non‐insulin‐dependent diabetes mellitus | European Journal of Clinical Investigation | 1997 | 346 |
| 23 | Cellular microparticles: new players in the field of vascular disease? | European Journal of Clinical Investigation | 2004 | 339 |
| 24 | Systemic immune‐inflammation index (SII) predicted clinical outcome in patients with coronary artery disease | European Journal of Clinical Investigation | 2020 | 338 |
| 25 | The TyG index may predict the development of cardiovascular events | European Journal of Clinical Investigation | 2016 | 325 |
| 26 | Human serum amyloid A (SAA) protein: a prominent acute‐phase reactant for clinical practice | European Journal of Clinical Investigation | 1996 | 319 |
| 27 | Effects of a cinnamon extract on plasma glucose, HbA1c, and serum lipids in diabetes mellitus type 2 | European Journal of Clinical Investigation | 2006 | 318 |
| 28 | The Inhibitory Effect of Phosphonates on the Formation of Calcium Phosphate Crystals in vitro and on Aortic and Kidney Calcification in vivo | European Journal of Clinical Investigation | 1970 | 315 |
| 29 | Vitamin D and calcium deficits predispose for multiple chronic diseases | European Journal of Clinical Investigation | 2005 | 311 |
| 30 | Abnormal intestinal motility in diabetics with the gastroparesis syndrome | European Journal of Clinical Investigation | 1984 | 310 |
| 31 | Scopolamine model of dementia: electroencephalogram findings and cognitive performance | European Journal of Clinical Investigation | 1998 | 310 |
| 32 | New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology | European Journal of Clinical Investigation | 2004 | 304 |
| 33 | Longitudinal study of bone mineral content in the lumbar spine, the forearm and the lower extremities after spinal cord injury | European Journal of Clinical Investigation | 1990 | 303 |
| 34 | The novel Chinese coronavirus (2019‐nCoV) infections: Challenges for fighting the storm | European Journal of Clinical Investigation | 2020 | 295 |
| 35 | Coronavirus disease 2019: The harms of exaggerated information and non‐evidence‐based measures | European Journal of Clinical Investigation | 2020 | 295 |
| 36 | Predictors of adverse prognosis in COVID‐19: A systematic review and meta‐analysis | European Journal of Clinical Investigation | 2020 | 289 |
| 37 | Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status | European Journal of Clinical Investigation | 1992 | 287 |
| 38 | Patients with achalasia lack nitric oxide synthase in the gastro‐oesophageal junction | European Journal of Clinical Investigation | 1993 | 287 |
| 39 | The role of glutathione in the regulation of apoptosis | European Journal of Clinical Investigation | 1999 | 286 |
| 40 | Estimation of Angiotensin II Concentration in Human Plasma by Radioimmunoassay. Some Applications to Physiological and Clinical States | European Journal of Clinical Investigation | 1971 | 284 |
| 41 | Serum levels of C‐reactive protein in Crohn's disease and ulcerative colitis | European Journal of Clinical Investigation | 1982 | 283 |
| 42 | Plasma and Brain Amino Acids in Fulminant Hepatic Failure and their Relationship to Hepatic Encephalopathy | European Journal of Clinical Investigation | 1976 | 272 |
| 43 | Lipoprotein Lp(a) as predictor of myocardial infarction in comparison to fibrinogen, LDL cholesterol and other risk factors: results from the prospective Göttingen Risk Incidence and Prevalence Study (GRIPS) | European Journal of Clinical Investigation | 1994 | 270 |
| 44 | Frailty predicts long-term mortality in elderly subjects with chronic heart failure | European Journal of Clinical Investigation | 2005 | 269 |
| 45 | The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia | European Journal of Clinical Investigation | 2003 | 268 |
| 46 | Encapsulated fish oil enriched in α-tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions | European Journal of Clinical Investigation | 2000 | 260 |
| 47 | The evolution of β‐cell dysfunction and insulin resistance in type 2 diabetes | European Journal of Clinical Investigation | 2002 | 258 |
| 48 | Kinetic bases of the primar hperlipidaemias: studies of apolipoprotein B turnover in geneticall defined subjects | European Journal of Clinical Investigation | 1980 | 257 |
| 49 | Iron and immunity: a double‐edged sword | European Journal of Clinical Investigation | 2002 | 256 |
| 50 | Cyclooxygenase‐2‐positive macrophages infiltrate the Alzheimer’s disease brain and damage the blood–brain barrier | European Journal of Clinical Investigation | 2002 | 253 |
