| # | Title | Journal | Year | Citations |
|---|
| 1 | Fluorine in Medicinal Chemistry | ChemBioChem | 2004 | 1,321 |
| 2 | The Unique Role of Fluorine in the Design of Active Ingredients for Modern Crop Protection | ChemBioChem | 2004 | 1,120 |
| 3 | Big Effects from Small Changes: Possible Ways to Explore Nature's Chemical Diversity | ChemBioChem | 2002 | 968 |
| 4 | Hydrogenases: Hydrogen-Activating Enzymes | ChemBioChem | 2002 | 740 |
| 5 | Design of Gold Nanoparticle‐Based Colorimetric Biosensing Assays | ChemBioChem | 2008 | 701 |
| 6 | Giant Vesicles: Preparations and Applications | ChemBioChem | 2010 | 624 |
| 7 | Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV | ChemBioChem | 2020 | 612 |
| 8 | Coiled Coil Domains: Stability, Specificity, and Biological Implications | ChemBioChem | 2004 | 611 |
| 9 | Structure and Function of Mammalian DNA Methyltransferases | ChemBioChem | 2011 | 561 |
| 10 | Extracellular Synthesis of Gold Nanoparticles by the Fungus Fusarium oxysporum | ChemBioChem | 2002 | 560 |
| 11 | Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA Methyltransferases | ChemBioChem | 2002 | 559 |
| 12 | Drug Design Strategies for Targeting G-Protein-Coupled Receptors | ChemBioChem | 2002 | 509 |
| 13 | Close-Range Electrostatic Interactions in Proteins | ChemBioChem | 2002 | 472 |
| 14 | Chemical Biology of the Sugar Code | ChemBioChem | 2004 | 466 |
| 15 | NMR Spectroscopy of RNA | ChemBioChem | 2003 | 428 |
| 16 | The Polar Hydrophobicity of Fluorinated Compounds | ChemBioChem | 2004 | 405 |
| 17 | Organic Fluorine: Odd Man Out | ChemBioChem | 2004 | 385 |
| 18 | The Outstanding Biological Stability ofβ- andγ-Peptides toward Proteolytic Enzymes: An In Vitro Investigation with Fifteen Peptidases | ChemBioChem | 2001 | 381 |
| 19 | The α-to-β Conformational Transition of Alzheimer's Aβ-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of β Conformation Seeding | ChemBioChem | 2006 | 375 |
| 20 | Addressing the Numbers Problem in Directed Evolution | ChemBioChem | 2008 | 374 |
| 21 | Molecular Assembly of an Aptamer–Drug Conjugate for Targeted Drug Delivery to Tumor Cells | ChemBioChem | 2009 | 363 |
| 22 | S‐Adenosyl‐Methionine‐Dependent Methyltransferases: Highly Versatile Enzymes in Biocatalysis, Biosynthesis and Other Biotechnological Applications | ChemBioChem | 2012 | 335 |
| 23 | Insight Into the Kinetic of Amyloid β (1–42) Peptide Self‐Aggregation: Elucidation of Inhibitors’ Mechanism of Action | ChemBioChem | 2007 | 328 |
| 24 | Wall Teichoic Acid Function, Biosynthesis, and Inhibition | ChemBioChem | 2010 | 327 |
| 25 | Conserved Amino Acid Residues Correlating With Ketoreductase Stereospecificity in Modular Polyketide Synthases | ChemBioChem | 2003 | 323 |
| 26 | Ways of Assembling Complex Natural Products on Modular Nonribosomal Peptide Synthetases A list of abbreviations can be found at the end of the text. | ChemBioChem | 2002 | 311 |
| 27 | Backbone and Side-Chain13C and15N Signal Assignments of the α-Spectrin SH3 Domain by Magic Angle Spinning Solid-State NMR at 17.6 Tesla | ChemBioChem | 2001 | 302 |
| 28 | Gene Expression within Cell-Sized Lipid Vesicles | ChemBioChem | 2003 | 292 |
| 29 | Real-Time Polymerase Chain Reaction | ChemBioChem | 2003 | 291 |
| 30 | Chemical Protein Modification through Cysteine | ChemBioChem | 2016 | 291 |
| 31 | NMR Spectroscopy of Paramagnetic Metalloproteins | ChemBioChem | 2005 | 289 |
| 32 | Targeting Mitochondria with Organelle‐Specific Compounds: Strategies and Applications | ChemBioChem | 2009 | 289 |
| 33 | A Widely Distributed Bacterial Pathway for Siderophore Biosynthesis Independent of Nonribosomal Peptide Synthetases | ChemBioChem | 2005 | 287 |
| 34 | Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation | ChemBioChem | 2000 | 285 |
| 35 | Strategies for the Discovery of New Natural Products by Genome Mining | ChemBioChem | 2009 | 277 |
| 36 | Quorum Sensing and Quorum Quenching: The Yin and Yang of Bacterial Communication | ChemBioChem | 2009 | 273 |
| 37 | RNA Interference and Small Interfering RNAs | ChemBioChem | 2001 | 271 |
| 38 | Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns | ChemBioChem | 2005 | 271 |
| 39 | 1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors | ChemBioChem | 2005 | 262 |
| 40 | Extracellular Synthesis of Crystalline Silver Nanoparticles and Molecular Evidence of Silver Resistance from Morganella sp.: Towards Understanding Biochemical Synthesis Mechanism | ChemBioChem | 2008 | 261 |
| 41 | Quantum-Dot Aptamer Beacons for the Detection of Proteins | ChemBioChem | 2005 | 258 |
| 42 | Copper and Zinc Binding to Amyloid‐β: Coordination, Dynamics, Aggregation, Reactivity and Metal‐Ion Transfer | ChemBioChem | 2009 | 257 |
| 43 | Genetic Control by Metabolite-Binding Riboswitches | ChemBioChem | 2003 | 254 |
| 44 | Use of Magnetic Nanoparticles as Nanosensors to Probe for Molecular Interactions | ChemBioChem | 2004 | 249 |
| 45 | Natural Products from Marine Organisms and Their Associated Microbes | ChemBioChem | 2006 | 247 |
| 46 | Redox Chemistry of Copper–Amyloid-β: The Generation of Hydroxyl Radical in the Presence of Ascorbate is Linked to Redox-Potentials and Aggregation State | ChemBioChem | 2007 | 245 |
| 47 | Azobenzene as Conformational Switch in Model Peptides | ChemBioChem | 2006 | 244 |
| 48 | Rapid and Quantitative Cyclization of Multiple Peptide Loops onto Synthetic Scaffolds for Structural Mimicry of Protein Surfaces | ChemBioChem | 2005 | 241 |
| 49 | Chemical Strategies for Activity-Based Proteomics | ChemBioChem | 2004 | 240 |
| 50 | Development of SNAP‐Tag Fluorogenic Probes for Wash‐Free Fluorescence Imaging | ChemBioChem | 2011 | 237 |
