# | Title | Journal | Year | Citations |
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1 | The Warburg Effect: How Does it Benefit Cancer Cells? | Trends in Biochemical Sciences | 2016 | 3,019 |
2 | Multiple sequence alignment with Clustal X | Trends in Biochemical Sciences | 1998 | 2,468 |
3 | RASMOL: biomolecular graphics for all | Trends in Biochemical Sciences | 1995 | 2,429 |
4 | Structure, mechanism and regulation of peroxiredoxins | Trends in Biochemical Sciences | 2003 | 2,285 |
5 | Genomic DNA methylation: the mark and its mediators | Trends in Biochemical Sciences | 2006 | 2,190 |
6 | Caspases: killer proteases | Trends in Biochemical Sciences | 1997 | 2,182 |
7 | Oxidative stress shortens telomeres | Trends in Biochemical Sciences | 2002 | 2,129 |
8 | The P-loop — a common motif in ATP- and GTP-binding proteins | Trends in Biochemical Sciences | 1990 | 1,999 |
9 | Mechanism and Regulation of NLRP3 Inflammasome Activation | Trends in Biochemical Sciences | 2016 | 1,993 |
10 | PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization | Trends in Biochemical Sciences | 1999 | 1,991 |
11 | Macromolecular crowding: obvious but underappreciated | Trends in Biochemical Sciences | 2001 | 1,986 |
12 | Nuclear targeting sequences — a consensus? | Trends in Biochemical Sciences | 1991 | 1,953 |
13 | Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death | Trends in Biochemical Sciences | 2017 | 1,911 |
14 | Intrinsically unstructured proteins | Trends in Biochemical Sciences | 2002 | 1,868 |
15 | Protein misfolding, evolution and disease | Trends in Biochemical Sciences | 1999 | 1,858 |
16 | AU-rich elements: characterization and importance in mRNA degradation | Trends in Biochemical Sciences | 1995 | 1,834 |
17 | The economics of ribosome biosynthesis in yeast | Trends in Biochemical Sciences | 1999 | 1,662 |
18 | The Nrf2 regulatory network provides an interface between redox and intermediary metabolism | Trends in Biochemical Sciences | 2014 | 1,591 |
19 | NPS@: Network Protein Sequence Analysis | Trends in Biochemical Sciences | 2000 | 1,468 |
20 | PEST sequences and regulation by proteolysis | Trends in Biochemical Sciences | 1996 | 1,461 |
21 | The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation | Trends in Biochemical Sciences | 2011 | 1,423 |
22 | Glutamine addiction: a new therapeutic target in cancer | Trends in Biochemical Sciences | 2010 | 1,422 |
23 | The glamour and gloom of glycogen synthase kinase-3 | Trends in Biochemical Sciences | 2004 | 1,400 |
24 | Dali: a network tool for protein structure comparison | Trends in Biochemical Sciences | 1995 | 1,390 |
25 | Okadaic acid: a new probe for the study of cellular regulation | Trends in Biochemical Sciences | 1990 | 1,332 |
26 | Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation | Trends in Biochemical Sciences | 2005 | 1,285 |
27 | Understanding, improving and using green fluorescent proteins | Trends in Biochemical Sciences | 1995 | 1,284 |
28 | Promoter-specific activation of RNA polymerase II transcription by Sp1 | Trends in Biochemical Sciences | 1986 | 1,181 |
29 | The leucine-rich repeat: a versatile binding motif | Trends in Biochemical Sciences | 1994 | 1,172 |
30 | The regulation of protein function by multisite phosphorylation – a 25 year update | Trends in Biochemical Sciences | 2000 | 1,108 |
31 | The WD repeat: a common architecture for diverse functions | Trends in Biochemical Sciences | 1999 | 1,101 |
32 | New insights into TGF-β–Smad signalling | Trends in Biochemical Sciences | 2004 | 1,097 |
33 | The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling | Trends in Biochemical Sciences | 2003 | 1,093 |
34 | Ten years of protein kinase B signalling: a hard Akt to follow | Trends in Biochemical Sciences | 2001 | 1,091 |
35 | Regulation of autophagy by ROS: physiology and pathology | Trends in Biochemical Sciences | 2011 | 1,076 |
36 | Mammalian cyclin-dependent kinases | Trends in Biochemical Sciences | 2005 | 1,069 |
37 | Coiled coils: new structures and new functions | Trends in Biochemical Sciences | 1996 | 1,067 |
38 | The MAP kinase cascade is essential for diverse signal transduction pathways | Trends in Biochemical Sciences | 1993 | 1,061 |
39 | The measurement and mechanism of lipid peroxidation in biological systems | Trends in Biochemical Sciences | 1990 | 1,052 |
40 | Protein kinase recognition sequence motifs | Trends in Biochemical Sciences | 1990 | 1,036 |
41 | The pentose phosphate pathway and cancer | Trends in Biochemical Sciences | 2014 | 1,018 |
42 | Moonlighting proteins | Trends in Biochemical Sciences | 1999 | 1,017 |
43 | The AMP-activated protein kinase cascade – a unifying system for energy control | Trends in Biochemical Sciences | 2004 | 1,015 |
44 | A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance | Trends in Biochemical Sciences | 1998 | 999 |
45 | TPR proteins: the versatile helix | Trends in Biochemical Sciences | 2003 | 994 |
46 | Conservation of gene order: a fingerprint of proteins that physically interact | Trends in Biochemical Sciences | 1998 | 991 |
47 | Oncogenic alterations of metabolism | Trends in Biochemical Sciences | 1999 | 989 |
48 | G proteins | Trends in Biochemical Sciences | 1992 | 984 |
49 | Parallel signal processing among mammalian MAPKs | Trends in Biochemical Sciences | 1995 | 968 |
50 | Ion motive ATPases. I. Ubiquity, properties, and significance to cell function | Trends in Biochemical Sciences | 1987 | 966 |