| # | Title | Journal | Year | Citations |
|---|
| 1 | Rapid analysis of amino acids using pre-column derivatization | Biomedical Applications | 1984 | 2,333 |
| 2 | Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection | Biomedical Applications | 1987 | 953 |
| 3 | Aqueous two-phase systems for protein separation | Biomedical Applications | 1998 | 697 |
| 4 | Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum | Biomedical Applications | 1991 | 613 |
| 5 | Variation in volatile organic compounds in the breath of normal humans | Biomedical Applications | 1999 | 612 |
| 6 | Sensitive high-performance liquid chromatographic determination of ionic drugs in biological fluids with short-wavelength ultraviolet detection using column switching combined with ion-pair chromatography: application to basic compounds | Biomedical Applications | 1989 | 568 |
| 7 | Use of magnetic techniques for the isolation of cells | Biomedical Applications | 1999 | 496 |
| 8 | Identification of multiple sources of charge heterogeneity in a recombinant antibody | Biomedical Applications | 2001 | 444 |
| 9 | Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids | Biomedical Applications | 1981 | 426 |
| 10 | Single cell gel electrophoresis assay: methodology and applications | Biomedical Applications | 1999 | 426 |
| 11 | Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine | Biomedical Applications | 1982 | 389 |
| 12 | Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in urine | Biomedical Applications | 1987 | 376 |
| 13 | High-performance liquid chromatographic determination of plasma and brain histamine without previous purification of biological samples: Cation-exchange chromatography coupled with post-column derivatization fluorometry | Biomedical Applications | 1985 | 372 |
| 14 | Validation of chromatographic methods in biomedical analysis viewpoint and discussion | Biomedical Applications | 1997 | 362 |
| 15 | Determination of ochratoxin A at the ppt level in human blood, serum, milk and some foodstuffs by high-performance liquid chromatography with enhanced fluorescence detection and immunoaffinity column cleanup: methodology and Swiss data | Biomedical Applications | 1995 | 334 |
| 16 | Validation of liquid chromatographic and gas chromatographic methods Applications to pharmacokinetics | Biomedical Applications | 1996 | 327 |
| 17 | Molecular imprinting for drug bioanalysis | Biomedical Applications | 2000 | 318 |
| 18 | Determination of catecholamines in rat heart tissue and plasma samples by liquid chromatography with electrochemical detection | Biomedical Applications | 1982 | 316 |
| 19 | High-performance capillary electrophoresis in the biological sciences | Biomedical Applications | 1989 | 311 |
| 20 | Gas chromatographic analysis of fatty acid methyl esters | Biomedical Applications | 1995 | 308 |
| 21 | Cyclodextrins: a versatile tool in separation science | Biomedical Applications | 2000 | 308 |
| 22 | Determination of amino acids in biological, pharmaceutical, plant and food samples by automated precolumn derivatization and high-performance liquid chromatography | Biomedical Applications | 1988 | 305 |
| 23 | Separation and sensing based on molecular recognition using molecularly imprinted polymers | Biomedical Applications | 1999 | 300 |
| 24 | Drug-protein binding studies new trends in analytical and experimental methodology | Biomedical Applications | 1996 | 296 |
| 25 | Improved method for the determination of propofol in blood by high-performance liquid chromatography with fluorescence detection | Biomedical Applications | 1987 | 291 |
| 26 | Oriented immobilization of biologically active proteins as a tool for revealing protein interactions and function | Biomedical Applications | 1999 | 291 |
| 27 | Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation | Biomedical Applications | 1990 | 290 |
| 28 | Simultaneous determination of retinol, α-tocopherol and β-carotene in serum by isocratic high-performance liquid chromatography | Biomedical Applications | 1991 | 284 |
| 29 | Structure and properties of ovalbumin | Biomedical Applications | 2001 | 283 |
| 30 | High-performance liquid chromatographic procedure for the simultaneous determination of the natural polyamines and their monoacetyl derivatives | Biomedical Applications | 1980 | 281 |
| 31 | Determination of free amino acid enantiomers in rat brain and serum by high-performance liquid chromatography after derivatization with N-tert.-butyloxycarbonyl-l-cysteine and o-phthaldialdehyde | Biomedical Applications | 1992 | 281 |
| 32 | Profiling steroid hormones and urinary steroids | Biomedical Applications | 1986 | 271 |
| 33 | Evaluation of the relative efficacy of various techniques for deproteinizing plasma samples prior to high-performance liquid chromatographic analysis | Biomedical Applications | 1981 | 268 |
| 34 | Determination of morphine, morphine-3-glucuronide and (tentatively) morphine-6-glucuronide in plasma and urine using ion-pair high-performance liquid chromatography | Biomedical Applications | 1982 | 260 |
| 35 | Measurement of vitamin A and vitamin E in human serum by high-performance liquid chromatography | Biomedical Applications | 1982 | 255 |
| 36 | Simultaneous determination of dopamine, dopac and homovanillic acid | Biomedical Applications | 1980 | 249 |
| 37 | Simultaneous determination of allantoin and oxypurines in biological fluids by high-performance liquid chromatography | Biomedical Applications | 1992 | 244 |
| 38 | Testing for drugs of abuse in saliva and sweat | Biomedical Applications | 1998 | 238 |
| 39 | Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2–3 μm Spherisorb ODS II column | Biomedical Applications | 1993 | 237 |
| 40 | Chloroformates in gas chromatography as general purpose derivatizing agents | Biomedical Applications | 1998 | 234 |
| 41 | Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography | Biomedical Applications | 1979 | 232 |
| 42 | High-performance liquid chromatographic separation of human haemoglobins | Biomedical Applications | 1988 | 226 |
| 43 | Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: Improved separation systems for polyamines in cerebrospinal fluid, urine and tissue | Biomedical Applications | 1986 | 225 |
| 44 | Derivatization procedures for gas chromatographic–mass spectrometric determination of xenobiotics in biological samples, with special attention to drugs of abuse and doping agents | Biomedical Applications | 1998 | 223 |
| 45 | Molecular imprinting: developments and applications in the analytical chemistry field | Biomedical Applications | 2000 | 217 |
| 46 | Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detection | Biomedical Applications | 1994 | 213 |
| 47 | Stability of food allergens and allergenicity of processed foods | Biomedical Applications | 2001 | 212 |
| 48 | Systematic toxicological analysis of drugs and their metabolites by gas chromatography—mass spectrometry | Biomedical Applications | 1992 | 210 |
| 49 | Profiling of human body fluids in healthy and diseased states using gas chromatography and mass spectrometry, with special reference to organic acids | Biomedical Applications | 1977 | 207 |
| 50 | Sample preparation for biomedical analysis | Biomedical Applications | 1989 | 207 |
