| # | Title | Journal | Year | Citations |
|---|
| 1 | Isolation and cultivation of Lyme disease spirochetes | Yale Journal of Biology and Medicine | 1984 | 1,423 |
| 2 | Hypothalamic control of food intake in rats and cats | Yale Journal of Biology and Medicine | 1951 | 858 |
| 3 | Causation and disease: the Henle-Koch postulates revisited | Yale Journal of Biology and Medicine | 1976 | 452 |
| 4 | Vancomycin Resistance in
| Yale Journal of Biology and Medicine | 2017 | 333 |
| 5 | Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia | Yale Journal of Biology and Medicine | 2007 | 326 |
| 6 | Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered | Yale Journal of Biology and Medicine | 1970 | 317 |
| 7 | Experimental Hypothalamic Hyperphagia in the Albino Rat | Yale Journal of Biology and Medicine | 1943 | 301 |
| 8 | Fractals in physiology and medicine | Yale Journal of Biology and Medicine | 1987 | 274 |
| 9 | Platelet-rich plasma: support for its use in wound healing | Yale Journal of Biology and Medicine | 2010 | 270 |
| 10 | Why cancer and inflammation? | Yale Journal of Biology and Medicine | 2006 | 267 |
| 11 | Experimental endocarditis I. Staphylococcal endocarditis in rabbits resulting from placement of a polyethylene catheter in the right side of the heart | Yale Journal of Biology and Medicine | 1970 | 261 |
| 12 | Observations related to pathogensis of dengue hemorrhagic fever. VI. Hypotheses and discussion | Yale Journal of Biology and Medicine | 1970 | 255 |
| 13 | Neuromuscular electrical stimulation for skeletal muscle function | Yale Journal of Biology and Medicine | 2012 | 251 |
| 14 | Excitation-contraction coupling in muscular response | Yale Journal of Biology and Medicine | 1952 | 215 |
| 15 | The problem of specificity in growth and development | Yale Journal of Biology and Medicine | 1947 | 204 |
| 16 | Therapeutic siRNA: principles, challenges, and strategies | Yale Journal of Biology and Medicine | 2012 | 199 |
| 17 | The Significance of the Default Mode Network (DMN) in Neurological and Neuropsychiatric Disorders: A Review | Yale Journal of Biology and Medicine | 2016 | 196 |
| 18 | Food intake as a mechanism of temperature regulation | Yale Journal of Biology and Medicine | 1948 | 195 |
| 19 | Basilar Impression (Platybasia): A Bizarre Developmental Anomaly of the Occipital Bone and Upper Cervical Spine with Striking and Misleading Neurologic Manifestations | Yale Journal of Biology and Medicine | 1939 | 193 |
| 20 | Recent advances in postoperative pain management | Yale Journal of Biology and Medicine | 2010 | 180 |
| 21 | Global burden of cancer | Yale Journal of Biology and Medicine | 2006 | 178 |
| 22 | Experimental endocarditis. II. Staphylococcal infection of the aortic valve following placement of a polyethylene catheter in the left side of the heart | Yale Journal of Biology and Medicine | 1971 | 174 |
| 23 | Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management | Yale Journal of Biology and Medicine | 2015 | 173 |
| 24 | Emerging Functions of Circular RNAs | Yale Journal of Biology and Medicine | 2016 | 173 |
| 25 | Microbial persistence | Yale Journal of Biology and Medicine | 1958 | 169 |
| 26 | Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis | Yale Journal of Biology and Medicine | 2012 | 166 |
| 27 | Prostaglandin E as the neural mediator of the febrile response | Yale Journal of Biology and Medicine | 1986 | 165 |
| 28 | Gain weight by "going diet?" Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010 | Yale Journal of Biology and Medicine | 2010 | 164 |
| 29 | Cytochalasin B reversibly inhibits phagocytosis: functional, metabolic, and ultrastructural effects in human blood leukocytes and rabbit alveolar macrophages | Yale Journal of Biology and Medicine | 1971 | 161 |
| 30 | Influenza A: understanding the viral life cycle | Yale Journal of Biology and Medicine | 2009 | 160 |
| 31 | Suicide attempts in the Epidemiologic Catchment Area Study | Yale Journal of Biology and Medicine | 1988 | 151 |
| 32 | Strategies for dealing with missing data in clinical trials: from design to analysis | Yale Journal of Biology and Medicine | 2013 | 148 |
| 33 | Influence of body weight and body fat on appetite of "normal" lean and obese rats | Yale Journal of Biology and Medicine | 1962 | 145 |
| 34 | On immunosurveillance in human cancer | Yale Journal of Biology and Medicine | 1982 | 144 |
| 35 | Penicillin's Discovery and Antibiotic Resistance: Lessons for the Future? | Yale Journal of Biology and Medicine | 2017 | 136 |
| 36 | Avian and mammalian hosts for spirochete-infected ticks and insects in a Lyme disease focus in Connecticut | Yale Journal of Biology and Medicine | 1984 | 135 |
| 37 | The discovery of the body: human dissection and its cultural contexts in ancient Greece | Yale Journal of Biology and Medicine | 1992 | 132 |
| 38 | Severe infections caused by Propionibacterium acnes: an underestimated pathogen in late postoperative infections | Yale Journal of Biology and Medicine | 1996 | 131 |
| 39 | Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? | Yale Journal of Biology and Medicine | 1993 | 126 |
| 40 | The role of microRNAs in cancer | Yale Journal of Biology and Medicine | 2006 | 123 |
| 41 | The effect of DOCA on electrolyte balance in normal man and its relation to sodium chloride intake | Yale Journal of Biology and Medicine | 1952 | 123 |
| 42 | The Flexner Report--100 years later | Yale Journal of Biology and Medicine | 2011 | 122 |
| 43 | How radiotherapy was historically used to treat pneumonia: could it be useful today? | Yale Journal of Biology and Medicine | 2013 | 116 |
| 44 | Is fever beneficial? | Yale Journal of Biology and Medicine | 1986 | 111 |
| 45 | The metabolism of fructose in man | Yale Journal of Biology and Medicine | 1956 | 107 |
| 46 | Molecular biology of pigment cells. Molecular controls in mammalian pigmentation | Yale Journal of Biology and Medicine | 1973 | 105 |
| 47 | Circulatory by-pass of the right heart. I. Preliminary observations on the direct delivery of vena caval blood into the pulmonary arterial circulation; azygos vein-pulmonary artery shunt | Yale Journal of Biology and Medicine | 1954 | 100 |
| 48 | The controversy surrounding bone morphogenetic proteins in the spine: a review of current research | Yale Journal of Biology and Medicine | 2014 | 99 |
| 49 | Benign clear cell ("sugar") tumors of the lung | Yale Journal of Biology and Medicine | 1971 | 98 |
| 50 | Clinical epidemiology and natural history of gastroesophageal reflux disease | Yale Journal of Biology and Medicine | 1999 | 97 |
