| 1 | Staging of brain pathology related to sporadic Parkinson’s disease | Neurobiology of Aging | 2003 | 7,578 |
| 2 | Staging of alzheimer's disease-related neurofibrillary changes | Neurobiology of Aging | 1995 | 1,718 |
| 3 | Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories | Neurobiology of Aging | 1997 | 1,268 |
| 4 | Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly | Neurobiology of Aging | 2017 | 1,063 |
| 5 | New stereological methods for counting neurons | Neurobiology of Aging | 1993 | 822 |
| 6 | Consensus Recommendations for the Postmortem Diagnosis of Alzheimer’s Disease | Neurobiology of Aging | 1997 | 776 |
| 7 | Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment | Neurobiology of Aging | 2006 | 774 |
| 8 | Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging | Neurobiology of Aging | 2010 | 760 |
| 9 | Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease | Neurobiology of Aging | 2003 | 737 |
| 10 | Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis | Neurobiology of Aging | 2009 | 727 |
| 11 | Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease | Neurobiology of Aging | 1997 | 703 |
| 12 | Effects of age on tissues and regions of the cerebrum and cerebellum | Neurobiology of Aging | 2001 | 699 |
| 13 | Components of postural dyscontrol in the elderly: A review | Neurobiology of Aging | 1989 | 695 |
| 14 | The impact of age, weight and gender on BDNF levels in human platelets and plasma | Neurobiology of Aging | 2005 | 691 |
| 15 | Midlife blood pressure and dementia: the Honolulu–Asia aging study☆ | Neurobiology of Aging | 2000 | 688 |
| 16 | Oxidative stress in brain agingImplications for therapeutics of neurodegenerative diseases | Neurobiology of Aging | 2002 | 643 |
| 17 | Age-related alterations in white matter microstructure measured by diffusion tensor imaging | Neurobiology of Aging | 2005 | 639 |
| 18 | The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease | Neurobiology of Aging | 1991 | 628 |
| 19 | Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling | Neurobiology of Aging | 2010 | 622 |
| 20 | Neuron numbers and dendritic extent in normal aging and Alzheimer's disease | Neurobiology of Aging | 1987 | 598 |
| 21 | Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI | Neurobiology of Aging | 2011 | 578 |
| 22 | Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease | Neurobiology of Aging | 1998 | 572 |
| 23 | Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease | Neurobiology of Aging | 1988 | 569 |
| 24 | Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death1 | Neurobiology of Aging | 2002 | 550 |
| 25 | Emerging roles of oxidative stress in brain aging and Alzheimer's disease | Neurobiology of Aging | 2021 | 539 |
| 26 | Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume | Neurobiology of Aging | 2004 | 533 |
| 27 | Measures of brain morphology and infarction in the framingham heart study: establishing what is normal | Neurobiology of Aging | 2005 | 519 |
| 28 | Sex, stress and the hippocampus: allostasis, allostatic load and the aging process | Neurobiology of Aging | 2002 | 514 |
| 29 | Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype | Neurobiology of Aging | 2006 | 512 |
| 30 | Vascular risk factors for Alzheimer’s disease: | Neurobiology of Aging | 2000 | 502 |
| 31 | Effects of age on volumes of cortex, white matter and subcortical structures | Neurobiology of Aging | 2005 | 501 |
| 32 | Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease | Neurobiology of Aging | 2009 | 500 |
| 33 | Hippocampus and entorhinal cortex in mild cognitive impairment and early AD | Neurobiology of Aging | 2004 | 489 |
| 34 | Glia and their cytokines in progression of neurodegeneration | Neurobiology of Aging | 2005 | 483 |
| 35 | PET imaging of amyloid deposition in patients with mild cognitive impairment | Neurobiology of Aging | 2008 | 477 |
| 36 | Consensus Report of the Working Group on: “Molecular and Biochemical Markers of Alzheimer’s Disease” | Neurobiology of Aging | 1998 | 473 |
| 37 | Regionally specific loss of neurons in the aging human hippocampus | Neurobiology of Aging | 1993 | 466 |
| 38 | Common mechanisms of amyloid oligomer pathogenesis in degenerative disease | Neurobiology of Aging | 2006 | 466 |
| 39 | Identification of normal and pathological aging in prospectively studied nondemented elderly humans | Neurobiology of Aging | 1992 | 464 |
| 40 | Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer’s disease | Neurobiology of Aging | 2003 | 463 |
| 41 | Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease | Neurobiology of Aging | 2012 | 451 |
| 42 | Resting state fMRI in Alzheimer's disease: beyond the default mode network | Neurobiology of Aging | 2012 | 448 |
| 43 | Physical activity, fitness, and gray matter volume | Neurobiology of Aging | 2014 | 439 |
| 44 | Neocortical glial cell numbers in human brains | Neurobiology of Aging | 2008 | 434 |
| 45 | The role of cerebral ischemia in Alzheimer’s disease | Neurobiology of Aging | 2000 | 431 |
| 46 | Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis | Neurobiology of Aging | 2006 | 431 |
| 47 | Spatial learning and motor deficits in aged rats | Neurobiology of Aging | 1984 | 422 |
| 48 | Memory improvement following induced hyperinsulinemia in alzheimer's disease | Neurobiology of Aging | 1996 | 422 |
| 49 | ApoE genotype accounts for the vast majority of AD risk and AD pathology | Neurobiology of Aging | 2004 | 419 |
| 50 | Deregulation of sphingolipid metabolism in Alzheimer's disease | Neurobiology of Aging | 2010 | 419 |