29.7(top 0.1%)
impact factor
10.0K(top 2%)
papers
1.4M(top 1%)
citations
542(top 0.1%)
h-index
32.1(top 1%)
extended IF
18.6K
all documents
1.5M
doc citations
934(top 0.1%)
g-index

Top Articles

#TitleJournalYearCitations
1Full-length transcriptome assembly from RNA-Seq data without a reference genomeNature Biotechnology201118,090
2Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationNature Biotechnology201014,198
3MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantificationNature Biotechnology200813,477
4Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2Nature Biotechnology201912,956
5Integrative genomics viewerNature Biotechnology201112,409
6Integrating single-cell transcriptomic data across different conditions, technologies, and speciesNature Biotechnology20189,679
7StringTie enables improved reconstruction of a transcriptome from RNA-seq readsNature Biotechnology20159,345
8Predictive functional profiling of microbial communities using 16S rRNA marker gene sequencesNature Biotechnology20138,414
9Near-optimal probabilistic RNA-seq quantificationNature Biotechnology20167,902
10Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotypeNature Biotechnology20197,823
113D bioprinting of tissues and organsNature Biotechnology20145,401
12Principles of nanoparticle design for overcoming biological barriers to drug deliveryNature Biotechnology20155,199
13The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cellsNature Biotechnology20145,076
14Spatial reconstruction of single-cell gene expression dataNature Biotechnology20154,733
15Quantitative analysis of complex protein mixtures using isotope-coded affinity tagsNature Biotechnology19994,687
16Large-scale analysis of the yeast proteome by multidimensional protein identification technologyNature Biotechnology20014,566
17In vivo cancer targeting and imaging with semiconductor quantum dotsNature Biotechnology20044,504
18Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent proteinNature Biotechnology20044,214
19Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineeringNature Biotechnology20054,130
20Sensitive detection of somatic point mutations in impure and heterogeneous cancer samplesNature Biotechnology20134,096
21DNA targeting specificity of RNA-guided Cas9 nucleasesNature Biotechnology20134,085
22Molecular Beacons: Probes that Fluoresce upon HybridizationNature Biotechnology19963,987
23GREAT improves functional interpretation of cis-regulatory regionsNature Biotechnology20103,977
24Renal clearance of quantum dotsNature Biotechnology20073,893
25Delivery of siRNA to the mouse brain by systemic injection of targeted exosomesNature Biotechnology20113,784
26Next-generation DNA sequencingNature Biotechnology20083,675
27Dimensionality reduction for visualizing single-cell data using UMAPNature Biotechnology20193,600
28Nonlinear magic: multiphoton microscopy in the biosciencesNature Biotechnology20033,583
29Antimicrobial and host-defense peptides as new anti-infective therapeutic strategiesNature Biotechnology20063,578
30SignalP 5.0 improves signal peptide predictions using deep neural networksNature Biotechnology20193,566
31A clearer vision for in vivo imagingNature Biotechnology20013,459
32Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9Nature Biotechnology20163,430
33What is flux balance analysis?Nature Biotechnology20103,369
34Differential analysis of gene regulation at transcript resolution with RNA-seqNature Biotechnology20133,337
35Assembly of long, error-prone reads using repeat graphsNature Biotechnology20193,190
36Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signalingNature Biotechnology20093,144
37An economic method for the fluorescent labeling of PCR fragmentsNature Biotechnology20003,137
38PICRUSt2 for prediction of metagenome functionsNature Biotechnology20203,120
39Fabrication of novel biomaterials through molecular self-assemblyNature Biotechnology20033,081
40Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular NetworkingNature Biotechnology20163,065
41Expression monitoring by hybridization to high-density oligonucleotide arraysNature Biotechnology19963,057
42A cross-platform toolkit for mass spectrometry and proteomicsNature Biotechnology20123,018
43What is a support vector machine?Nature Biotechnology20062,963
44The use of nanocrystals in biological detectionNature Biotechnology20042,869
45High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cellsNature Biotechnology20132,843
46A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of lifeNature Biotechnology20182,798
47CRISPR-Cas systems for editing, regulating and targeting genomesNature Biotechnology20142,726
48Efficient genome editing in zebrafish using a CRISPR-Cas systemNature Biotechnology20132,712
49Determining cell type abundance and expression from bulk tissues with digital cytometryNature Biotechnology20192,701
50Generation of induced pluripotent stem cells without Myc from mouse and human fibroblastsNature Biotechnology20082,614